NIA Core Center to Build Neurodegenerative Disease Research Faculty At Penn

描述（由申请人提供）：宾夕法尼亚大学（PENN）在与衰老相关的神经退行性疾病方面拥有强大的跨学科研究项目，对与衰老相关的神经退行性疾病有基本的了解，并实施项目，制定预防或改善阿尔茨海默氏症（AD）和帕金森病（PD），肌萎缩性侧索硬化症（ALS）和额颞叶变性（FTLD）的策略。P30神经退行性疾病核心中心将通过招募两名新教师来进一步建立宾夕法尼亚大学神经退行性疾病研究人员的多学科社区，他们的专业知识将补充现有的项目，同时为这些项目增加新的内容。这包括神经病学终身教职教师，他们擅长神经退行性疾病的基因组研究，以及实验神经病理学终身教职教师，他们擅长阐明代谢综合征对阿尔茨海默病风险增加的贡献。这将通过在全国范围内寻找这些教师以及指导计划和机构支持来完成，以无缝地将这些新教师整合到宾夕法尼亚大学神经退行性疾病研究项目网络中。这将创造新的就业机会，并通过改善对AD、PD、FTLD、ALS和相关疾病患者的护理，提高降低医疗保健费用的能力。

DESCRIPTION (provided by applicant): The University of Pennsylvania (PENN) has strong interdisciplinary research programs on aging related neurodegenerative disorders that develop basic insights Into aging related neurodegenerative disease and Implement programs for developing strategies to prevent or ameliorate Alzheimer's (AD) and Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), and front temporal lobar degeneration (FTLD). This P30 Neurodegenerative Disease Core Center will build further the multidisciplinary community of neurodegenerative disease researchers at PENN by recruiting two new faculty whose expertise complements existing programs while adding new content to these programs. This includes a tenure track Neurology faculty with expertise In genomic studies of neurodegenerative diseases and a tenure track experimental Neuropathology faculty with expertise in elucidating contributions of the metabolic syndrome to Increased risk for AD. This will be accomplished through a national search for these faculty as well as mentoring programs and institutional support to seamlessly integrate these new faculty into the PENN neurodegenerative disease research program network. This will lead to new job creation and enhanced capacity to reduce health care costs by improving the care of patients with AD, PD, FTLD, ALS and related disorders. PUBLIC HEALTH RELEVANCE: Completing the Aims of this P30 Neurodegenerative Disease Core Center will build further the multidisciplinary community of neurodegenerative disease researchers at PENN by recruiting two new faculty members whose expertise complements existing PENN programs while adding new content to these programs. This will lead to new job creation and enhanced capacity to reduce health care costs by improving the care of patients with aging related neurodegenerative disorders such as Alzheimer's and Parkinson's disease, amyotrophic lateral sclerosis, and frontotemporal lobar degeneration thereby stimulating economic growth.