NIA Core Center to Build Neurodegenerative Disease Research Faculty At Penn

NIA 核心中心将在宾夕法尼亚大学建立神经退行性疾病研究人员

• 批准号: 7858939
• 负责人: JOHN Q. TROJANOWSKI
• 金额: $ 40.19万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-30 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7858939
• 关键词: Affect; Aging; Alzheimer' s Disease; Amyotrophic Lateral Sclerosis; Communities; Complement; Diabetes Mellitus; Disease; Economics; Elements; Environment; Faculty; Frontotemporal Lobar Degenerations; Genomics; Growth; Health; Health Care Costs; Interdisciplinary Study; Lead; Lobar; Mentors; Metabolic syndrome; Nervous system structure; Neurodegenerative Disorders; Neurology; Obesity; Occupations; Parkinson Disease; Patient Care; Pennsylvania; Positioning Attribute; Recruitment Activity; Research; Research Personnel; Research Project Grants; Risk; Scientist; Seasons; Universities; age related; body system; improved; insight; member; multidisciplinary; neuropathology; prevent; programs; public health relevance; ranpirnase

DESCRIPTION (provided by applicant): The University of Pennsylvania (PENN) has strong interdisciplinary research programs on aging related neurodegenerative disorders that develop basic insights Into aging related neurodegenerative disease and Implement programs for developing strategies to prevent or ameliorate Alzheimer's (AD) and Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), and front temporal lobar degeneration (FTLD). This P30 Neurodegenerative Disease Core Center will build further the multidisciplinary community of neurodegenerative disease researchers at PENN by recruiting two new faculty whose expertise complements existing programs while adding new content to these programs. This includes a tenure track Neurology faculty with expertise In genomic studies of neurodegenerative diseases and a tenure track experimental Neuropathology faculty with expertise in elucidating contributions of the metabolic syndrome to Increased risk for AD. This will be accomplished through a national search for these faculty as well as mentoring programs and institutional support to seamlessly integrate these new faculty into the PENN neurodegenerative disease research program network. This will lead to new job creation and enhanced capacity to reduce health care costs by improving the care of patients with AD, PD, FTLD, ALS and related disorders. PUBLIC HEALTH RELEVANCE: Completing the Aims of this P30 Neurodegenerative Disease Core Center will build further the multidisciplinary community of neurodegenerative disease researchers at PENN by recruiting two new faculty members whose expertise complements existing PENN programs while adding new content to these programs. This will lead to new job creation and enhanced capacity to reduce health care costs by improving the care of patients with aging related neurodegenerative disorders such as Alzheimer's and Parkinson's disease, amyotrophic lateral sclerosis, and frontotemporal lobar degeneration thereby stimulating economic growth.

描述（由申请人提供）：宾夕法尼亚大学（PENN）在与衰老相关的神经退行性疾病方面拥有强大的跨学科研究项目，这些项目开发了与衰老相关的神经退行性疾病的基本见解，并实施了用于开发预防或改善阿尔茨海默病（AD）和帕金森病（PD）、肌萎缩侧索硬化症（ALS）和前颞叶变性（FTLD）的策略的项目。这个P30神经退行性疾病核心中心将通过招募两名新教师来进一步建立宾夕法尼亚州神经退行性疾病研究人员的多学科社区，他们的专业知识补充了现有的课程，同时为这些课程增加了新的内容。这包括一个在神经退行性疾病的基因组研究方面具有专业知识的终身制神经病学教师和一个在阐明代谢综合征对AD风险增加的贡献方面具有专业知识的终身制实验神经病理学教师。这将通过对这些教师的全国性搜索以及指导计划和机构支持来实现，以将这些新教师无缝整合到PENN神经退行性疾病研究计划网络中。这将创造新的就业机会，并通过改善AD、PD、FTLD、ALS和相关疾病患者的护理来提高降低医疗保健成本的能力。 公共卫生相关性：完成这个P30神经退行性疾病核心中心的目标将进一步建立神经退行性疾病研究人员的多学科社区在宾夕法尼亚州通过招募两名新的教师，其专业知识补充现有的宾夕法尼亚州计划，同时增加新的内容，这些程序。这将创造新的就业机会，并通过改善对老年性神经退行性疾病（如阿尔茨海默氏症和帕金森氏症、肌萎缩性侧索硬化症和额颞叶变性）患者的护理，提高降低保健费用的能力，从而刺激经济增长。