Mentored research in the intersection of kidney and cardiovascular disease

肾脏和心血管疾病交叉领域的指导研究

• 批准号: 10795588
• 负责人: Nisha Bansal
• 金额: $ 10.97万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-06 至 2028-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10795588
• 关键词: Academia; Acute Renal Failure with Renal Papillary Necrosis; Address; Administrative Supplement; Alaska; American Indians; Arrhythmia; Asian Americans; Award; Awareness; Cardiovascular Diseases; Chronic Kidney Failure; Clinical; Clinical Trials; Coupled; Development; Diagnosis; Dialysis procedure; Disease; Disparity; Education; Educational Status; Endowment; Ethnic Origin; Family; Fellowship; Foundations; Functional disorder; Funding; Future; Gender; Geography; Grant; Growth; Heart failure; Idaho; Individual; Journals; Kidney Diseases; Kidney Failure; Kidney Transplantation; Leadership; Lesbian Gay Bisexual Transgender Queer; Measures; Medicine; Mentors; Mentorship; Mission; Montana; National Institute of Diabetes and Digestive and Kidney Diseases; Nephrology; Pacific Islander; Patients; Persons; Philosophy; Physicians; Postdoctoral Fellow; Productivity; Publications; Publishing; Race; Research; Research Infrastructure; Research Support; Resources; Scholarship; Science; Scientist; Socioeconomic Status; Source; Students; Talents; Time; Training; Underrepresented Populations; United States National Institutes of Health; Universities; Washington; Woman; Work; Wyoming; career; doctoral student; education research; epidemiology study; health equity; hypertension treatment; interest; next generation; outreach program; patient oriented research; post-doctoral training; professor; programs; racial diversity; racism; risk stratification; rural area; sex; success; training opportunity

ABSTRACT I am a mid-career nephrologist, a newly promoted Professor, the holder of Arthur Stach Endowed Professorship and the Director of Nephrology Clinical and Research Education in the Division of Nephrology at the University of Washington (UW). I have been a NIDDK-funded physician-scientist since the completion of my fellowship in 2010; and have an active patient-oriented research program that focuses on the intersection of kidney and cardiovascular disease. My work encompasses epidemiological studies, mechanistic studies, and clinical trials all focused on the pathophysiology, diagnosis, risk stratification and treatment of hypertension, heart failure and cardiac arrhythmias in patients with chronic kidney disease, acute kidney injury and kidney failure (treated with dialysis or kidney transplant). I am currently the PI of three NIH R01s, the co- Director of the UW Nephrology NIDDK T32, co-I on two NIH U01s and the PI of two NIH administrative supplements. One of the greatest joys and privileges of my career to date has been the opportunity to serve as mentor. My success as a mentor is measured by my mentee’s success. My current and previous grants have provided numerous rich opportunities for training for post-doctoral students, residents and fellows. I have been a mentor for 24 talented individuals since 2010, including 63% women, 50% Asian American persons, 30% persons underrepresented in medicine or science by race, ethnicity, gender identify and family educational status. Of these, 63% of my mentees remain in academia and continue in scholarship or research. The work of these mentees has been productive, yielding >40 first author publications and ten NIH or foundation grants. There is a critical need to increase mentorship for individuals from diverse backgrounds. It is well known that advances in NIDDK-focused diseases are in crisis as fewer physician and scientists choose to pursue research careers. In particular, diverse research teams are needed to address racism and disparities in medicine and science. Mentorship is a critical factor cited by students for inspiring their interest in scientific careers. Locally, the UW, located in Seattle, WA, is unique in its mission to attract trainees from across a five-state region of Washington, Wyoming, Alaska, Montana and Idaho, who are diverse by race (including American Indian and Pacific Islander), ethnicity, sex, gender, geography (many from rural areas), ability, LGBTQ+ and socioeconomic status. Coupled with established outreach programs at UW and the sizable pool of post- doctoral trainees from these diverse backgrounds, there is tremendous opportunity to cultivate the next generation of NIDDK diverse scientists in this region. I am committed to mentoring persons from backgrounds underrepresented in medicine and science to increase the diversity of the future NIDDK biomedical scientific workforce. This award will provide key resources, training and professional development that will enhance my ability to serve as an effective mentor for post-doctoral trainees from diverse backgrounds.

摘要 我是一名职业生涯中期的肾病学家，是一名新晋升的教授，是Arthur Stach Endowed的持有者 教授职务及肾内科临床与研究教育主任 华盛顿大学(UW)。我一直是NIDDK资助的内科科学家 我在2010年获得了奖学金；并有一个积极的以患者为导向的研究计划，专注于交叉点 肾脏和心血管疾病。我的工作包括流行病学研究，机械学研究， 临床试验都集中在病理生理学、诊断、风险分层和治疗上。 慢性肾脏病、急性肾损伤患者的高血压、心力衰竭和心律失常 和肾衰竭(通过透析或肾移植治疗)。我目前是三个NIH R01的PI，联合- UW肾病NIDDK T32主任，两个NIH U01和两个NIH行政部门的PI的协理-I 补充剂。到目前为止，我职业生涯中最大的乐趣和特权之一就是有机会担任 门托。作为一名导师，我的成功是以我被辅导者的成功来衡量的。 我现在和以前的资助为博士后培训提供了无数丰富的机会 学生、居民和研究员。自2010年以来，我已经成为24名有才华的人的导师，其中63% 女性，50%的亚裔美国人，30%的人在医学或科学领域的种族代表性不足， 种族、性别认同和家庭教育状况。在这些学生中，63%的学生仍然留在学术界和 继续从事学术或研究工作。这些被辅导者的工作卓有成效&>40第一作者 出版物和10个国家卫生研究院或基金会的赠款。 迫切需要加强对来自不同背景的个人的指导。众所周知， 随着越来越少的医生和科学家选择从事研究，以NIDDK为重点的疾病的进展处于危机之中 事业。特别是，需要不同的研究小组来解决种族主义和医学上的差异以及 科学。导师是学生们提到的一个关键因素，可以激发他们对科学职业的兴趣。在当地， 华盛顿大学位于华盛顿州西雅图，其使命是吸引来自五个州地区的学员 华盛顿州、怀俄明州、阿拉斯加州、蒙大拿州和爱达荷州，他们的种族是多样化的(包括美国印第安人和 太平洋岛民)、种族、性别、性别、地理位置(许多来自农村地区)、能力、LGBTQ+和 社会经济地位。再加上威斯康星大学建立的外展计划和相当大的职位池 来自这些不同背景的博士生，有巨大的机会培养下一代 这一地区的一代NIDDK多样化的科学家。我致力于指导来自不同背景的人 在医学和科学方面的代表性不足，以增加未来NIDDK生物医学科学的多样性 劳动力。该奖项将提供关键资源、培训和专业发展，以增强我的 有能力为来自不同背景的博士后学员提供有效的指导。