Facility Management, Maintenance and Operation Core

设施管理、维护和运营核心

基本信息

  • 批准号:
    10793908
  • 负责人:
  • 金额:
    $ 133.84万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2023
  • 资助国家:
    美国
  • 起止时间:
    2023-08-18 至 2028-07-31
  • 项目状态:
    未结题

项目摘要

Project Summary: The BSL3 suites in the Rocky Mountain Regional Biocontainment Laboratory (RMRBL) at Colorado State University (CSU) have been operational and at capacity since being commissioned. These facilities support research in response to new threats from established pathogens, such as Mycobacterium spp. (tuberculosis, leprosy, and emerging diseases caused by non-tuberculosis mycobacteria) and high consequence, select agent pathogens, such as Eastern Equine Encephalitis Virus, Venezuelan Equine Encephalitis, Francisella tularensis, and Burkholderia pseudomallei. The RMRBL BSL3 is required to pivot and rapidly respond to new, emerging pathogens with pandemic potential. The RMRBL has been exemplary, researching new threats such as MERS-CoV, MPox, and SARS-CoV-2. The RMRBL BSL3 thus represents the backbone of research capabilities in infectious disease at CSU. CSU, in turn has supported the facility for the past 15 years. CSU’s support includes much of the day-to-day operating costs of the RMRBL BSL3 facilities; remaining costs are covered by assessing user fees to CSU researchers based on square footage and entries. Expenses beyond day-to-day operational costs, including non-annual facilities repairs and replacement upgrades require additional advocating and are addressed when eminently needed. This disrupts crucial operations. Work within the BSL3 comes with a sacrifice to personal comfort due to the requirements for biosafety and biosecurity, along with the inherent risk of work on high consequence pathogens. Maintaining safe, operational and appropriate scientific instruments is challenged as servicing these instruments is difficult and frequently results in the need to replace equipment. The consequence of the cost, work environment, deprecating equipment and operational disruptions is our inability to maintain a trained workforce and sufficiently technically equipped BSL3 ‘warm ready’ space. In response to this challenge, we propose our Core 1 – Facility Management, Maintenance & Operations. This core is strategically designed to resolve many of the RMRBL BSL3 challenges through three functional aims; Aim 1 - Management, will improve upon the current structure for communication across research and support teams; Aim 2 – Maintenance, will maintain the RMRBL BSL3 facilities functionality through proactive preventative maintenance, reducing unplanned disruptions; and finally, Aim 3 – Operations, will institute dedicated operational and animal husbandry support and improve IT-communications within the RMRBL BSL3/ABSL3. Our comprehensive approach to improving the management, maintenance, and operations of the RMRBL BSL3 will result in an improved RMRBL BSL3 system that exemplifies communication and collaboration across our diverse leadership and research teams in a biosafe and bio-secure compliant environment. As a result, the penultimate goal of this core - to perpetuate warm ready RMRBL BSL3 facilities; compliant with the dynamic requirements for biosafety and biosecurity, appropriately resourced, and responsive to our national and state RBL mission – will be achieved.
项目摘要:落基山区域生物遏制实验室(RMRBL)中的BSL3套件 科罗拉多州立大学(CSU)自投入使用以来一直在运营并达到了饱和状态。这些 设施支持研究以应对来自已有病原体的新威胁,如分枝杆菌 SPP.(结核病、麻风和由非结核分枝杆菌引起的新出现的疾病)和高 结果,精选病原体,如东方马脑炎病毒、委内瑞拉马 脑炎、图拉氏方济氏菌和假鼻疽伯克霍尔德氏菌。RMRBL BSL3需要旋转和 对新出现的具有大流行潜力的病原体迅速作出反应。RMRBL一直是模范, 研究新的威胁,如MERS-CoV、MPox和SARS-CoV-2。因此,RMRBLBSL3代表 CSU传染病研究能力的中坚力量。CSU反过来又支持该设施用于 过去的15年里。CSU的支持包括RMRBL BSL3设施的大部分日常运营费用; 剩余成本通过根据平方英尺和条目评估向CSU研究人员支付的用户费用来支付。 超出日常业务费用的费用,包括非年度设施维修和更换 升级需要额外的宣传,并在最需要的时候得到解决。这中断了至关重要的 行动。在BSL3内工作的同时,由于以下要求,牺牲了个人舒适度 生物安全和生物安保,以及研究高后果病原体的固有风险。维护 安全、可操作和适当的科学仪器面临挑战,因为维护这些仪器很困难。 并且经常导致需要更换设备。成本、工作环境、 设备和运营中断的不利之处在于我们无法维持训练有素的员工队伍和 装备有足够技术的BSL3“热准备”空间。为了应对这一挑战,我们提出了我们的核心 1-设施管理、维护和运营。这一核心经过战略性设计,旨在解决许多 RMRBL BSL3通过三个职能目标提出的挑战;目标1--管理,将在目前的基础上改进 研究和支持团队之间的沟通结构;目标2--维护,将维持 RMRBL BSL3设施通过主动预防性维护实现功能,减少计划外 中断;最后,目标3--业务,将建立专门的业务和畜牧业支助 并改善RMRBL BSL3/ABSL3内的IT通信。我们全面的改进方法 RMRBLBSL3的管理、维护和运营将导致RMRBLBSL3得到改进 该系统体现了我们的不同领导和研究团队之间的沟通和协作 一个符合生物安全和生物安全的环境。因此,这个核心的倒数第二个目标--永久化 热备RMRBL BSL3设施;符合生物安全和生物安保的动态要求, 我们将获得适当的资源,并响应我们国家和州的RBL使命。

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ monograph.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ sciAawards.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ conferencePapers.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ patent.updateTime }}

Raymond Paul Goodrich其他文献

Raymond Paul Goodrich的其他文献

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

相似海外基金

Conference: Rethinking how language background is described in academia and beyond
会议:重新思考学术界及其他领域如何描述语言背景
  • 批准号:
    2335912
  • 财政年份:
    2024
  • 资助金额:
    $ 133.84万
  • 项目类别:
    Standard Grant
ADVANCE Catalyst: Virtual Observatory of Culture for Equity in Academia at the University of Puerto Rico Rio Piedras (VoCEA)
ADVANCE Catalyst:波多黎各 Rio Piedras 大学学术界平等文化虚拟观察站 (VoCEA)
  • 批准号:
    2214418
  • 财政年份:
    2023
  • 资助金额:
    $ 133.84万
  • 项目类别:
    Standard Grant
Comprehensive development strategy of modality-specific "intellectual property" and "cultivation" with an eye on "pharmaceutical affairs" in academia drug discovery
学术界新药研发着眼“药事”的模式“知识产权”与“培育”综合发展策略
  • 批准号:
    23K02551
  • 财政年份:
    2023
  • 资助金额:
    $ 133.84万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Accelerating Research Advancement for Investigators Underrepresented in Academia
加速学术界代表性不足的研究人员的研究进展
  • 批准号:
    10746315
  • 财政年份:
    2023
  • 资助金额:
    $ 133.84万
  • 项目类别:
Planning: HBCU-UP: Strengthening Data Science Research Capacity and Education Programs through Academia-Industry Partnership
规划:HBCU-UP:通过学术界与工业界合作加强数据科学研究能力和教育计划
  • 批准号:
    2332161
  • 财政年份:
    2023
  • 资助金额:
    $ 133.84万
  • 项目类别:
    Standard Grant
From Academia to Business: Development of Novel Therapeutics Against HPV-Associated Cancer
从学术界到商界:针对 HPV 相关癌症的新型疗法的开发
  • 批准号:
    10813323
  • 财政年份:
    2023
  • 资助金额:
    $ 133.84万
  • 项目类别:
Academics4Rail: Building a community of railway scientific researchers and academia for ERJU and enabling a network of PhDs (academia teaming with industry)
Academys4Rail:为ERJU建立铁路科研人员和学术界社区并建立博士网络(学术界与工业界合作)
  • 批准号:
    10087488
  • 财政年份:
    2023
  • 资助金额:
    $ 133.84万
  • 项目类别:
    EU-Funded
Academics4Rail: Building a Community of Railway Scientific Researchers and Academia for ERJU and Enabling a Network of PhDs (Academia Teaming with Industry)
Academys4Rail:为二院建立铁路科研人员和学术界社区并启用博士网络(学术界与工业界合作)
  • 批准号:
    10102850
  • 财政年份:
    2023
  • 资助金额:
    $ 133.84万
  • 项目类别:
    EU-Funded
Exploring the overall picture of industry-academia-government collaboration: A spectrum of knowledge transfer through formal and informal channels
探索产学官合作的整体图景:通过正式和非正式渠道进行的一系列知识转移
  • 批准号:
    22K01692
  • 财政年份:
    2022
  • 资助金额:
    $ 133.84万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Fostering Ethical Neurotechnology Academia-Industry Partnerships: A Stakeholder Engagement and Toolkit Development Project
促进道德神经技术学术界与工业界的伙伴关系:利益相关者参与和工具包开发项目
  • 批准号:
    10655632
  • 财政年份:
    2022
  • 资助金额:
    $ 133.84万
  • 项目类别:
{{ showInfoDetail.title }}

作者:{{ showInfoDetail.author }}

知道了