Facility Management, Maintenance and Operation Core
设施管理、维护和运营核心
基本信息
- 批准号:10793908
- 负责人:
- 金额:$ 133.84万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2023
- 资助国家:美国
- 起止时间:2023-08-18 至 2028-07-31
- 项目状态:未结题
- 来源:
- 关键词:2019-nCoVAcademiaAddressAdministrative SupplementAdvocateAgingAnimal HusbandryAwardBasic ScienceBiologicalBiological SciencesBurkholderia pseudomalleiCalibrationCapitalCareer ChoiceCategoriesCertificationClientCollaborationsColoradoCommunicable DiseasesCommunicationConflict (Psychology)Cyclic GMPDataDedicationsDisciplineDiseaseEastern Equine Encephalitis VirusEconomic BurdenEducationEmerging Communicable DiseasesEnsureEntrepreneurshipEnvironmentEquipmentEvaluationFeesFoundationsFrancisella tularensisFundingGenus MycobacteriumGoalsGood Manufacturing ProcessGovernment AgenciesGrantHazardous ChemicalsHazardous SubstancesHuman ResourcesIndustryInfectious Diseases ResearchInformation SystemsInformation TechnologyInfrastructureInstitutionInvestmentsLaboratoriesLeadershipLeprosyMaintenanceMelioidosisMiddle East Respiratory Syndrome CoronavirusMissionModernizationMonkeypoxNational Institute of Allergy and Infectious DiseaseOperations ResearchParentsPharmacologic SubstancePlagueProcessPublic HealthResearchResearch PersonnelResearch SupportResolutionResource AllocationResource DevelopmentResourcesRiskScienceServicesSiteStructureSystemTrainingTranslational ResearchTuberculosisTularemiaUniversitiesUpdateVenezuelan Equine EncephalomyelitisVertebral columnVeterinary MedicineVisionWorkWorkforce Developmentagedbiodefensebiosafety level 3 facilitybiosecuritycollegecostdesignemerging pathogenfaculty researchhealth economicsimprovedinstrumentlaboratory facilitymanufacturenon-tuberculosis mycobacteriaoperationpandemic diseasepandemic potentialpathogenpathogenic bacteriaprofessional atmosphereprogramsrepairedresponsesocioeconomicsusabilityviral pandemicvisiting scholar
项目摘要
Project Summary: The BSL3 suites in the Rocky Mountain Regional Biocontainment Laboratory (RMRBL) at
Colorado State University (CSU) have been operational and at capacity since being commissioned. These
facilities support research in response to new threats from established pathogens, such as Mycobacterium
spp. (tuberculosis, leprosy, and emerging diseases caused by non-tuberculosis mycobacteria) and high
consequence, select agent pathogens, such as Eastern Equine Encephalitis Virus, Venezuelan Equine
Encephalitis, Francisella tularensis, and Burkholderia pseudomallei. The RMRBL BSL3 is required to pivot and
rapidly respond to new, emerging pathogens with pandemic potential. The RMRBL has been exemplary,
researching new threats such as MERS-CoV, MPox, and SARS-CoV-2. The RMRBL BSL3 thus represents the
backbone of research capabilities in infectious disease at CSU. CSU, in turn has supported the facility for the
past 15 years. CSU’s support includes much of the day-to-day operating costs of the RMRBL BSL3 facilities;
remaining costs are covered by assessing user fees to CSU researchers based on square footage and entries.
Expenses beyond day-to-day operational costs, including non-annual facilities repairs and replacement
upgrades require additional advocating and are addressed when eminently needed. This disrupts crucial
operations. Work within the BSL3 comes with a sacrifice to personal comfort due to the requirements for
biosafety and biosecurity, along with the inherent risk of work on high consequence pathogens. Maintaining
safe, operational and appropriate scientific instruments is challenged as servicing these instruments is difficult
and frequently results in the need to replace equipment. The consequence of the cost, work environment,
deprecating equipment and operational disruptions is our inability to maintain a trained workforce and
sufficiently technically equipped BSL3 ‘warm ready’ space. In response to this challenge, we propose our Core
1 – Facility Management, Maintenance & Operations. This core is strategically designed to resolve many of the
RMRBL BSL3 challenges through three functional aims; Aim 1 - Management, will improve upon the current
structure for communication across research and support teams; Aim 2 – Maintenance, will maintain the
RMRBL BSL3 facilities functionality through proactive preventative maintenance, reducing unplanned
disruptions; and finally, Aim 3 – Operations, will institute dedicated operational and animal husbandry support
and improve IT-communications within the RMRBL BSL3/ABSL3. Our comprehensive approach to improving
the management, maintenance, and operations of the RMRBL BSL3 will result in an improved RMRBL BSL3
system that exemplifies communication and collaboration across our diverse leadership and research teams in
a biosafe and bio-secure compliant environment. As a result, the penultimate goal of this core - to perpetuate
warm ready RMRBL BSL3 facilities; compliant with the dynamic requirements for biosafety and biosecurity,
appropriately resourced, and responsive to our national and state RBL mission – will be achieved.
项目摘要:位于洛基山地区生物防护实验室(RMRBL)的BSL3套房
项目成果
期刊论文数量(0)
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