BSL-3 Practices Core

项目总结：落基山地区生物遏制实验室(RMRBL)必须维护 在生物安全和生物安保方面的卓越表现，以履行其应对公共健康和潜力的职责 生物恐怖主义紧急情况。更新、现代化并不断提高生物安全和 RMRBL的生物安全计划确保研究人员能够有效地为重要的 RBL网络的使命。该BSL-3实践核心将促进可持续发展的长期目标 高质量的生物安全和生物安保在RMRBL通过三个首要目标。目标1--连续 生物安全和生物安全在动态研究环境中的演变对保护 研究人员、社区和环境。这笔资金支持的努力将包括 运用通用设计原则和循证教学策略实现当前培训的现代化 以提高保持率。将开发新的反馈机制，以促进定期更新 根据不断变化的研究需求进行培训。应急和危机管理培训 将被放大，以便人员能够更好地根据标准操作自动做出反应 程序。这包括与外部应急管理合作伙伴就实时场景进行协调 和桌面练习。目标2--通过物质和物质基础设施的现代化来加强生物安全 行政基础设施将使当前的RMRBL生物安全系统保持最新，并提供强大的 全面生物安全计划的框架。跟上信息的快速变化 技术和全球互联互通是一个日益严峻的挑战。通过这个项目，RMRBL 生物安全计划将进行物理安全升级和行政支持扩大。 考虑到公众对高密封性实验室研究的认识不断提高，积极主动的变化 RMRBL生物安全计划将促进适应面对不断变化的监管 环境。这对于按照RBL网络的任务不断做好准备至关重要。目标3- 将加强与生物安全和生物安保最佳做法保持一致的行政控制 RMRBL人员的安全文化。与目标1、标准作业程序(SOP)协同， 将对计划、政策、做法和库存系统进行战略性审查和更新 强调研究人员的理解力和易用性。建立一致的反馈机制 对于用户来说，行政控制的有效性将增加买入。改进的新想法 RMRBL流程将在与其他RBL网络生物安全团队进行人员交流期间收集。 此外，将通过系统调查加强生物安全和生物安保最佳做法。 风险缓解战略的有效性。总而言之，这个核心将确保生物安全和生物安保 在皇家马格里布基地的活动具有时代性和灵活性，能够充分支持区域后勤基地网络的使命。

Project Summary: The Rocky Mountain Regional Biocontainment Laboratory (RMRBL) must maintain excellence in biosafety and biosecurity to fulfill its charge of responding to public health and potential bioterrorism emergencies. Updating, modernizing, and continuously improving the biosafety and biosecurity program at the RMRBL ensures that researchers can effectively contribute to the important mission of the RBL network. This BSL-3 Practices Core will facilitate the long-term goals for sustaining high quality biosafety and biosecurity in the RMRBL through three overarching aims. Aim 1- Continuous evolution of biosafety and biosecurity for a dynamic research environment is critical for protecting researchers, the community, and the environment. Efforts supported by this funding will include modernizing current training using universal design principles and evidence-based teaching strategies for improved retention. New feedback mechanisms will be developed to promote regular updates to training based on ever-changing research needs. Emergency response and crisis management training will be amplified so personnel are better equipped to automatically react according to standard operating procedures. This includes coordinating with external emergency management partners for live scenarios and table-top exercises. Aim 2- Enhancing biosecurity through modernization of physical and administrative infrastructure will bring current RMRBL biosecurity systems up to date and provide a robust framework for a comprehensive biosecurity program. Keeping up with rapid changes in information technology and global interconnectedness is an increasing challenge. Through this project, the RMRBL biosecurity program will undergo physical security upgrades and administrative support expansion. Considering the increased public awareness of high containment laboratory research, proactive changes to the RMRBL biosecurity program will facilitate adaptation in the face of a changing regulatory environment. This is essential for constant readiness in line with the mission of the RBL network. Aim 3- Strengthening administrative controls for alignment with biosafety and biosecurity best practices will build safety culture among RMRBL personnel. In synergy with Aim 1, standard operating procedures (SOPs), plans, policies, practices, and inventory systems will be strategically reviewed and updated with an emphasis on researcher comprehension and ease of use. Developing consistent feedback mechanisms for users about the effectiveness of administrative controls will increase buy-in. New ideas for improving RMRBL processes will be gathered during personnel exchanges with other RBL network biosafety teams. Additionally, biosafety and biosecurity best practices will be reinforced through systematic investigation of the effectiveness of risk mitigation strategies. In sum, this core will ensure that biosafety and biosecurity at the RMRBL is contemporary and flexible to adequately support the mission of the RBL network.