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ENVIONMENTAL AGENTS IN THE INDUCTION OF AUTOIMMUNITY

ENVIONMENTAL AGENTS IN THE INDUCTION OF AUTOIMMUNITY
诱导自身免疫的环境因素
批准号:
2018976
负责人:
JOEL SCHIFFENBAUER
金额:
$7.25万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1996
资助国家:
美国
项目状态:
已结题
起止时间:
1996-09-01 至 1998-08-31

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中文摘要
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英文摘要
DESCRIPTION: The primary objective of this proposal is to examine the effect of environmental toxicants that possess either estrogenic or antiestrogenic properties on: (1) the course of lupus in one autoimmune strain of mice with lupus, (2) the course of autoimmunity in diabetes-prone and diabetes-resistant mice, and (3) the ability of these agents to induce autoimmune renal disease in two normal strains of mice. These objectives will be addressed by administering estrogenic and antiestrogenic agents to mice, and then evaluating the effect on the production of autoantibodies, B cell proliferation and development of autoimmune pathology in the kidney and pancreas.
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Autoimmune toxicity of chlorinated compounds
  • 批准号:
    6664570
  • 项目类别:
  • 资助金额:
    $13.16万
  • 财政年份:
    2002
  • 负责人:
    JOEL SCHIFFENBAUER
  • 依托单位:
Autoimmune toxicity of chlorinated compounds
  • 批准号:
    6580398
  • 项目类别:
  • 资助金额:
    $13.16万
  • 财政年份:
    2002
  • 负责人:
    JOEL SCHIFFENBAUER
  • 依托单位:
Autoimmune toxicity of chlorinated compounds
  • 批准号:
    6443387
  • 项目类别:
  • 资助金额:
    $13.16万
  • 财政年份:
    2001
  • 负责人:
    JOEL SCHIFFENBAUER
  • 依托单位:
GENETIC LOCI CONTRIBUTING TO AUTOIMMUNITY IN BXSB MICE
  • 批准号:
    6201320
  • 项目类别:
  • 资助金额:
    $15.69万
  • 财政年份:
    1999
  • 负责人:
    JOEL SCHIFFENBAUER
  • 依托单位:
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