Administrative Core

杜克大学自动免疫卓越中心(ACE)的行政核心将提供领导 以及支持两个基础研究项目，即先导研究项目(如果获得批准)、5 正在进行的临床试验，以及经ACE指导委员会批准的任何新的临床试验。它的 总体目标将是促进这项综合基础和临床研究的目标 计划，确保个人资助项目的质量和进度，促进 基础和临床科学家，并促进研究成果的适当传播。这个 CORE将在E.William St.Clair博士(首席调查员)的指导下，他还将担任 临床研究代表。他将负责监督所有的预算事务 公爵王室，每月组织执行委员会会议，每年安排两次 ACE研究会议，并协调准备非竞争性续签申请。 泰德博士将担任副主任和基础研究代表 行政核心，并与圣克莱尔博士密切合作，管理ACE研究企业， 确保计划的相关性，并促进基础和临床科学家之间的互动。 塔米·卡迪尔(免疫科)和帕蒂·梅·戴维斯(风湿科和 免疫学)将为核心提供行政支持。他们将共同管理 小组，协调会议，与NIAID工作人员和负责 ACE酌情基金的管理。核心还将利用一个执行委员会来 确保项目的有效管理和整合，并协调年度审查 杜克大学ACE咨询委员会的研究活动。圣克莱尔博士和泰德博士将参加 加内特·凯尔索博士、拉塞尔·霍尔博士和大卫·皮塞茨基博士担任执行委员会成员。核心还将 支持教育活动，提高中心在杜克大学的知名度，并提供一个论坛 用于沟通和交流研究想法。行政核心将培育一个充满活力的、 临床和基础研究的互动计划，将促进我们对 自身免疫性疾病中的B细胞。

The Administrative Core of the Duke Autoimmunity Center of Excellence (ACE) will provide leadership and support for the two basic research projects, the Pilot Research Project (if approved), the 5 ongoing clinical trials, and any new clinical trials approved by ACE Steering Committee. Its overarching goal will be to promote the objectives of this integrated basic and clinical research program, ensure the quality and progress of the individual funded projects, foster interactions among basic and clinical scientists, and facilitate the appropriate dissemination of research findings. The core will be under the direction of Dr. E. William St.Clair (Principal Investigator) who will also serve as the Clinical Research Representative. He will be responsible for overseeing all budgetary matters of the Duke ACE, organizing monthly meetings of the Executive Committee, arranging for the twice yearly ACE research meetings, and coordinating the preparation of non-competitive renewal applications. Dr. Tedder will serve as the Associate Director and Basic Research Representative of the Administrative Core and work closely with Dr. St.Clair in managing the ACE research enterprise, ensuring program relevance, and facilitating interactions between the basic and clinical scientists. Tammy Caudil (Department of Immunology) and Patty Might Davis (Division of Rheumatology and Immunology) will provide administrative support for the core. Together, they will adminstrate the fmaces, coordinate meetings, interface with NIAID staff and the institution responsible for the management of the ACE Discretionary Fund. The core will also utilize an Executive Committee to ensure effective management and integration of the projects, as well as coordinate an annual review of the resarch activities by the Duke ACE Advisory Board. Drs. St.Clair and Tedder will be joined on the Executive committee by Drs. Garnett Kelsoe, Russell Hall, and David Pisetsky. The Core will also support educational activities to enhance the visibility of the Center within Duke and provide a forum for communicating and exchanging research ideas. The Administrative Core will nurture a vibrant, interactive program of clinical and basic research that will advance our understanding about the role of B cells in autoimmune disease.