Replication Repair
Replication Repair
批准号:
7593938
负责人:
JOHN W. DRAKE
金额:
$30.75万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至
关键词:
AffectBackBacteriophage T4BypassCell DeathClassDNA DamageDNA RepairDaughterDefectEventExcisionGeneticGenetic RecombinationHealthMethodsMinorModelingMutagenesisMutationNeighborhoodsOne-Step dentin bonding systemPaste substancePathway interactionsProcessPropertyProtein BindingRateReportingSingle-Stranded DNATestinghelicasemutantrecombinaserepaired
中文摘要
点击翻译按钮获取中文摘要
英文摘要
We reported previously that several mutations that abolish either of the two mechanisms of replication repair are general mutator mutations that sometimes promote templated mutations particularly strongly. Thus, defects in replication repair somehow promote template switching to an inappropriate template. We are now pursuing hypotheses making predictions about the properties of mutants carrying mutational blocks either in both pathways, or in both steps of one of the pathways. We are also testing whether each component of an imperfect reverse repeat can template mutations in the other component.
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专著(0)
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会议论文
Direct Isolation of Chromosomal Regions for the Study of Human Genes
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批准号:6106740
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:JOHN W. DRAKE
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依托单位:
Structural Basis of Polymerase Fidelity
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批准号:6106738
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:JOHN W. DRAKE
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依托单位:
Replication Repair
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批准号:6432368
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:JOHN W. DRAKE
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依托单位:
Structural Basis Of Polymerase Fidelity
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批准号:6838408
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:JOHN W. DRAKE
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依托单位:
Replication Repair
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批准号:6838410
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:JOHN W. DRAKE
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依托单位:
Rates Of Spontaneous Mutation
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批准号:6673202
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:JOHN W. DRAKE
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依托单位:
Rates Of Spontaneous Mutation
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批准号:7007429
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:JOHN W. DRAKE
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依托单位:
Rates Of Spontaneous Mutation
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批准号:7169972
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:JOHN W. DRAKE
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依托单位:
Rates Of Spontaneous Mutation
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批准号:7593941
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项目类别:
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资助金额:$67.09万
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财政年份:--
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负责人:JOHN W. DRAKE
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依托单位:
DIRECT ISOLATION OF CHROMOSOMAL REGIONS FOR THE STUDY OF HUMAN GENES
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批准号:6290036
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:JOHN W. DRAKE
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依托单位:
REPLICATION REPAIR
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批准号:6290035
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:JOHN W. DRAKE
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依托单位:
Structural Basis Of Polymerase Fidelity
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批准号:7169968
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:JOHN W. DRAKE
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依托单位:
Rates Of Spontaneous Mutation
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批准号:6508855
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:JOHN W. DRAKE
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依托单位:
Structural Basis of Polymerase Fidelity
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批准号:7968077
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项目类别:
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资助金额:$1.42万
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财政年份:--
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负责人:JOHN W. DRAKE
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依托单位:
Replication Repair
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批准号:7328443
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:JOHN W. DRAKE
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依托单位:
Rates Of Spontaneous Mutation
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批准号:7734477
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项目类别:
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资助金额:$101.13万
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财政年份:--
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负责人:JOHN W. DRAKE
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依托单位:
Structural Basis of Polymerase Fidelity
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批准号:7734473
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项目类别:
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资助金额:$2.63万
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财政年份:--
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负责人:JOHN W. DRAKE
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依托单位:
Structural Basis of Polymerase Fidelity
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批准号:6432367
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:JOHN W. DRAKE
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依托单位:
Replication Repair
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批准号:7968079
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项目类别:
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资助金额:$1.42万
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财政年份:--
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负责人:JOHN W. DRAKE
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依托单位:
Rates Of Spontaneous Mutation
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批准号:7328451
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:JOHN W. DRAKE
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依托单位:
国内基金
海外基金
患者依从性与脑卒中后跌倒风险相关性及“Teach-Back ”护理干预效应研究
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批准号:2026JJ81464
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项目类别:省市级项目
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资助金额:--
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批准年份:2026
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负责人:叶婷
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依托单位:
基于Teach-back药学科普模式的慢阻肺患者吸入用药依从性及疗效研究
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批准号:2024KP61
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项目类别:省市级项目
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资助金额:--
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批准年份:2024
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负责人:余丹
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依托单位:
基于Quench-Back保护的超导螺线管磁体失超过程数值模拟研究
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批准号:51307073
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项目类别:青年科学基金项目
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资助金额:25.0万元
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批准年份:2013
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负责人:郭兴龙
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依托单位: