Nutrient Absorption in Lean Versus Obese Individuals

瘦人和肥胖者的营养吸收

• 批准号: 7593778
• 负责人: Clifton Bogardus
• 金额: $ 24.16万
• 依托单位: NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7593778
• 关键词: Accounting; Calories; Collaborations; Cross-Sectional Studies; Daily; Diet; Energy Metabolism; Enteral; Feces; Goals; Individual; Large Intestine; Macronutrients Nutrition; Measurement; Nutrient; Obesity; Population; Regulation; Reproducibility; Sampling; Standards of Weights and Measures; Testing; Universities; Urine; Washington; Weight Gain; absorption

This study examines obese and lean individuals on two standard diets (which differ by calorie content) and the stool and urine energy losses to compare these values in lean versus obese individuals. The study is also investigating the specific macronutrient content of stool to examine differences in these parameters between lean and obese individuals. The repeatability of these measurements is also being tested in a subset of individuals. In collaboration with Dr. Jeffrey Gordons lab at Washington University in St. Louis, samples of stool will be sent for determination of the fecal bacterial flora phylotypes to examine the association between stool energy loss and enteric flora populations. Results of this study are expected in late 2008.

这项研究研究了肥胖和精益的人，以两种标准饮食（与卡路里含量不同）以及粪便和尿液能量损失，以比较瘦肉与肥胖个体中的这些价值。该研究还研究了粪便的特定大量营养素含量，以检查瘦和肥胖个体之间这些参数的差异。这些测量值的可重复性也在个人的一部分中进行了测试。与圣路易斯华盛顿大学的Jeffrey Gordons博士实验室合作，将发送粪便样品，以确定粪便细菌植物群的系统型，以检查粪便能量损失与肠子菌群种群之间的关联。这项研究的结果预计将在2008年底。