NATIONAL HIB BEHAVIORAL SURVEILLANCE (NHBS) SYSTEM

描述（由申请人提供）：国家艾滋病毒行为监测（NHBS）系统的目的是在艾滋病毒/艾滋病高发病率地区，以人口为基础，代表性的个人样本中，检查人类免疫缺陷病毒（HIV）感染前危险行为的流行情况。华盛顿特区是各州和地区新报告艾滋病病例流行率最高的地区，2005年每10万人中有128例;在大都市地区中排名第三。异性性接触是最常见的传播方式（31%），其次是男男性行为（MSM）（27%）和注射毒品（IDU）（18%）。卫生部/艾滋病毒/艾滋病管理局（DOH/HAA）和乔治华盛顿大学（GWU）建立了公共卫生/学术伙伴关系，以成功实施NHBS-HET-1，满足应计目标，最高度重视人类受试者保护、监测数据保护和社区参与; DOH/HAA将继续与GWU建立伙伴关系，开展NHBS-2。公共卫生的重要性的其他合作伙伴关系的成就包括卫生部/HAA和GWU教师和工作人员，社区成员，MPH学生和双语访谈者之间的合作;与当地艾滋病毒护理组织，社区宣传团体，居委会和预防机构的积极和有效的社区关系的发展;一个积极的社区咨询委员会的发展。该合作伙伴关系为当前和下一代公共卫生专业人员的培训和专业发展提供了独特的机会。在NHBS-2的拟议研究中，将进行三项连续的横断面研究，重点是MSM，IDU和异性恋者在艾滋病毒感染的高风险（HET）在每年的连续性。对于每个数据收集年，在机构审查委员会批准后，将进行广泛的定性评价，包括人种学评估和二次数据审查，以告知研究实施的文化能力和有效方法。每个研究年度将采用基于地点的时空抽样或受调查者驱动的抽样方法招募至少500名参与者;将由经过培训的工作人员在固定和移动的地点进行调查和艾滋病毒检测。HIV血清阳性率、风险和检测行为数据将每月提交给CDC。数据的快速分析和传播将使我们了解大都市华盛顿地区居民的行为以及预防策略。通过参与NHBS-2，我们将共同实现2010年健康人的目标，并为整体公共卫生和福利做出贡献。

Description (provided by applicant): The purpose of the National HIV Behavioral Surveillance (NHBS) system is to examine the prevalence of risk behaviors antecedent to human immunodeficiency virus (HIV) acquisition in a population-based, representative sample of individuals in areas with high HIV/AIDS rates. Washington, DC has the highest prevalence of newly reported AIDS cases of states and territories, with 128 cases per 100,000 in 2005; it ranks third among metropolitan areas. Heterosexual contact is the most frequently reported mode of transmission (31%), followed by men who have sex with men (MSM) (27%), and injection drug use (IDU) (18%). The Department of Health/HIV/AIDS Administration (DOH/HAA) and George Washington University (GWU) formed a Public Health/Academic Partnership to successfully implement NHBS-HET-1, meeting accrual goals with the highest regard for human subjects protection, protection of surveillance data, and community involvement; DOH/HAA will continue the Partnership with GWU to conduct NHBS-2. Other Partnership accomplishments of public health importance include collaborations among DOH/HAA and GWU faculty and staff, community members, MPH students, and bilingual interviewers; development of positive and effective community relationships with local HIV care organizations, community advocacy groups, neighborhood councils, and prevention agencies; development of an active Community Advisory Board. The Partnership provides a unique opportunity for the training and professional development of the current and next generation of public health professionals. In the proposed study for NHBS-2, three serial cross-sectional studies will be conducted, focusing on MSM, IDU, and heterosexuals at high risk for HIV infection (HET) in annual succession. For each data collection year, following Institutional Review Board approval, an extensive qualitative evaluation including an ethnographic assessment and secondary data review will be conducted to inform culturally competent and effective methods for study implementation. A minimum of 500 participants for each study year will be recruited using either venue-based, time and space sampling or respondent-driven sampling; survey implementation and HIV testing will be conducted by trained staff in fixed and mobile sites. HIV seroprevalence, risk, and testing behavior data will be forwarded to CDC monthly. Rapid analysis and dissemination of data will inform our understanding of behavior among residents of the metropolitan Washington, DC area as well as prevention strategies. Through the District's participation in NHBS-2, we will together meet the Healthy People 2010 objectives, and contribute to the public health and welfare overall.