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Studies Of Hereditary Neurological Disease: Clinical Trials

Studies Of Hereditary Neurological Disease: Clinical Trials
遗传性神经系统疾病的研究：临床试验
批准号：
7594728
负责人：
Kenneth Fischbeck
金额：
$135.32万
依托单位：
NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/7594728
关键词：
Androgen AntagonistsAntiandrogen TherapyBiological MarkersClinical ResearchClinical TrialsDevelopmentDiseaseDoseDutasterideFriedreich AtaxiaGoalsInheritedPatientsPhase II Clinical TrialsPurposeResearchSafetySeriesSpinal Muscular AtrophyTestingidebenonemouse modelnervous system disorderprogramsspinal and bulbar muscular atrophy

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中文摘要
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英文摘要
The purpose of this research program is to develop safe and effective treatments for hereditary neurological disorders. Specific research accomplishments in the past year include the following: (1) a collaborative study to establish reliable biomarkers for spinal muscular atrophy, (2) completion of a phase 2 study of high dose idebenone treatment for Friedreich's ataxia, and (3) development of a phase 2 clinical trial to test the feasibility of dutasteride treatment for spinal and bulbar muscular atrophy (Kennedy's disease).
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Studies of Hereditary Neurological Disease: Disease Mechanisms
Studies Of Hereditary Neurological Disease: Clinical Trials
Studies Of Hereditary Neurological Disease: Disease Gene Identification
Studies Of Hereditary Neurological Disease: Disease Gene Identification
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