Boston University Clinical and Translational Science Institute

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SUMMARY 1. Summary of the funded parent grant (BU CTSI) The overall theme of the Boston University Clinical and Translational Science Institute (BU CTSI) is to explore and solve major challenges in translational science, especially those that address the special health problems of disadvantage individuals from urban at risk communities by developing and deploying new tools, methods and processes to expedite clinical research in our hub and nationalize shared unique resources with the CTSA Network. To do this we will exploit our strengths in developing multi-disciplinary, multi-cultural collaborative teams across diverse programs. This approach follows on the BU CTSI’s history of actively engaging in continuous and vigorous dialogue within its own hub, with other CTSA hubs, and with NCATS to identify opportunities to catalyze clinical and translational research locally and nationally. Our goals are: Goal 1. Discover, demonstrate, deploy and disseminate novel programs to develop our entire translational science workforce. Goal 2. Further enhance our robust translational science environment to encourage all aspects of translational research, from scientific discovery to an efficient clinical research enterprise, exploiting our strengths in basic and clinical science, and in so doing address the health disparities of our at risk diverse patients and make the lessons learned and resources developed from our partners and affiliates available to the CTSA network. Goal 3. Effect meaningful multi-directional relationships among all our community stakeholders (patients, providers, purchasers, payers, public policy makers/advocates, product makers and principal investigators) to strengthen collaborative translational research across the lifespan of our special populations and enable novel approaches to integrating research into health care in our ACO. Goal 4. In collaboration with other CTSA Hubs, discover, develop and disseminate innovative tools, methods and programs to improve research on treatments and diagnostics that address our local and national health problems. Goal 5. Develop and demonstrate novel informatics innovations to Improve local Hub translational research in our unique learning health system and disseminate these innovations to the CTSA Network. The BU CTSI’s vision is to be the strongest possible advocate for, and participant in, translational research that serves the health needs of our diverse at risk URG patient populations by empowering our community and creating unique resources that can be integrated with and distributed to the national CTSA network.