Stanford Breast Metastasis Center Administrative Core

摘要/项目摘要 斯坦福大学乳房转移中心(SBMC)行政核心的运作将坚持以下原则 我们的成功依赖于一支协调良好、专注的多学科团队，执行一流的研究。我们的 核心团队拥有与来自以下机构的科学研究人员一起开展大型项目的良好记录 多个领域，包括癌症生物学、免疫学、功能基因组学、计算生物学、生物信息学 以及统计学、乳房内科肿瘤学、病理学、外科。通过我们的行政核心，我们将提供 通过执行三个目标来确定和回应短期和长期需求的监督。我们的首要目标是 是建立和维持一个有效和反应迅速的组织结构，以提供适当的 NCI转移网络内活动的沟通和协调。对于内部监督，我们将 召集执行委员会，包括患者权益倡导者、外部咨询委员会、内部咨询 委员会和指导委员会将定期举行会议，审查目前的进展，提出建议 并监控未来的进展。所有SBMC调查人员和工作人员都将参加每两周一次的SBMC 我们将在会议上发布PI、项目主管和核心主管的一般公告，审查我们的 里程碑，听取最新情况和我们的一名调查人员的深入介绍，然后进行讨论。我们 将维护最新的邮件列表和一个网站，以发布公告、归档摘要说明 会议，托管活动日历，并提供指向数据和模型存储库的链接。我们的第二个目标是 建立和维护沟通和物流战略，以实现透明和反应迅速的互动 SBMC、NCI Metnet和更广泛的科学界。以促进内部数据和方法的交换 其他组成气象网的中心，我们将积极参加每年一度的气象网调查员会议和 通过组织和参与协作活动和工作，为气象网的活动作出贡献 组。我们的第三个目标是促进对中心中期里程碑的评估，并在必要时实施 经NCI MetNet项目经理批准修订里程碑的流程。我们将在两个月内监测进展情况 通过我们的SBMC里程碑仪表板每周召开一次SBMC团队会议，它将总结我们 三个项目和核心。我们还将在NCI MetNet年会上报告里程碑的进展情况。第三，我们 将在NCI年度现场审查期间对我们中心的表现进行现场评估。最后，在不太可能的情况下 如果我们在实现里程碑方面遇到延迟，我们将实施一项解决战略，该战略将涉及 我们的团队和指导委员会，如有需要，还包括选管会、选管会、其他都市网中心和 美国国家情报局。

Abstract/Project Summary The Stanford Breast Metastasis Center (SBMC) Administrative Core will operate by upholding the principle that our success relies on a well coordinated and focused multidisciplinary team executing premier research. Our core team has an established track record of working on large scale projects with scientific investigators from multiple fields, including cancer biology, immunology, functional genomics, computational biology, bioinformatics and statistics, breast medical oncology, pathology, surgery. Through our Administrative Core, we will provide oversight that identifies and responds to short-term and long-term needs by executing three aims. Our first aim is to establish and maintain an effective and responsive organizational structure that provides proper communication and coordination of activities within the NCI Metastasis Network. For internal oversight, we will convene an Executive Committee, including patient advocates, External Advisory Committee, Internal Advisory Committee, and Steering Committee that will meet regularly to review current progress, make recommendations and monitor future progress. All SBMC investigators and staff will be expected to attend bi-weekly SBMC meetings where we will have general announcements by PIs, Project Leads and Core Leads, review our milestones, hear updates and an in-depth presentation from one of our investigators followed by discussion. We will maintain updated mailing lists and a website to disseminate announcements, archive summary notes from meetings, host a calendar of activities and provide links to data and model repositories. Our second aim is to establish and maintain a communication and logistics strategy for transparent and responsive interactions within the SBMC the NCI MetNet and the broader scientific community. To foster exchange of data and methods within other centers comprising the MetNet, we will actively participate in annual MetNet investigator meetings and contribute to the activities of the MetNet by organizing and participating in collaborative activities and working groups. Our third aim is to facilitate the evaluation of Center interim milestones and, if needed, implement processes to revise milestones with NCI MetNet Program Manager approval. We will monitor progress at bi- weekly SBMC team meetings through our SBMC Milestones Dashboard, which will summarize progress in our three Projects and Cores. We will also report progress on milestones at NCI MetNet annual meeting. Thirdly, we will host an onsite evaluation of our Center’s performance during annual NCI Site Reviews. Finally, in the unlikely event that we experience a delay in meeting our milestones, we will engage a resolution strategy that will involve our team and Steering Committee, and, as needed, the EAC, IAC, colleagues in other MetNet Centers and the NCI.