The Native Children's Research Exchange Scholars Program: Preparing the Next Generation of American Indian and Alaska Native Substance Abuse and Addition Scientists

项目总结/摘要 美洲印第安人和阿拉斯加原住民（AIAN）面临着一些最严重的药物滥用问题。 美国任何人口的不平等。美国国立卫生研究院加大了努力， 通过投资于研究，以了解根本原因，并在研究重点， 对这些人群进行预防和干预。其他努力包括建立部落 2015年，美国国立卫生研究院的健康研究办公室和启动了干预研究，以改善土著居民的健康状况。 2012年，美国卫生部。虽然正在取得进展，但它们是渐进的，许多人都在放缓 在研究不同的AIAN人群时遇到的复杂性。一个持续减弱的挑战 美国国立卫生研究院努力的有效性在于AIAN研究人员在研究中的代表性不足 问题研究AIAN主要调查员的队伍正在增长，但AIAN主要调查员的人数仍然很大， 代表性不足。虽然有一些训练有素的非本地PI与AIAN密切合作， 社区，使用有效的基于社区的前瞻性研究方法，以提高科学的严谨性 和相关性，这些研究的潜力，充分整合科学和文化 整个研究设计、测量、分析、解释和传播过程中的知识受到破坏 因为缺乏AIAN的领导。这个项目的目的是建立和扩大成功的本土 儿童研究交流学者（NCRE）计划，以支持AIAN的早期职业发展 药物滥用研究者NCRE学者于2012年开始在NCRE网络的基础上， 研究人员对AIAN儿童和青少年进行了研究。NCRE网络提供了一个平台， 为连接研究生，博士后，和初级教师的高级研究导师谁提供 实质性辅导和职业发展支助。该网络参加的NCRE会议提供了 一个分享信息和进一步建立合作关系的论坛。拟议项目将 通过以下方式支持下一代AIAN药物滥用和成瘾科学家的发展：（1） 维持NCRE学者计划，以支持5个队列中的10名额外学者，每个队列2名学者;（2） 保留成功的NCRE学者计划的基本组成部分，继续提供 通过建立和加强与NCRE网络有关的一小批学者的辅导， 实施量身定制的职业发展计划和支持写作目标;（3）扩大 在学者咨询委员会的指导下， 将与NCRE会议和结构化课程一起举办赠款编写讲习班， 与AIAN社区进行负责任的研究;以及（4）将一名小型NCRE学生纳入 指导努力与NCRE学者计划，以加强参与潜在的研究人员早在 教育管道（NCRE星级计划;学生思考研究职业）。

PROJECT SUMMARY/ABSTRACT American Indian and Alaska Native (AIAN) populations face some of the most significant substance abuse inequities of any population in the United States. The National Institutes of Health has increased efforts to address these inequities through investing in research to understand the root causes and in studies focused on prevention and intervention in these populations. Additional efforts include the establishment of the Tribal Health Research Office at the NIH in 2015 and the launch of the Intervention Research to Improve Native American Health Initiative in 2012. While gains are being made, they are incremental, slowed by many complexities encountered in research with diverse AIAN populations. A challenge that continues to attenuate the effectiveness of NIH's efforts is the underrepresentation of AIAN investigators at the helm of research studies. The cadre of AIAN Principal Investigators (PIs) is growing, but AIAN PIs remain significantly underrepresented. While there are a number of well-trained non-Native PIs who work closely with AIAN communities, using effective Community-Based Participatory Research approaches to enhance scientific rigor and relevance in these contexts, the potential of these studies to fully integrate scientific and cultural knowledge throughout study design, measurement, analysis, interpretation and dissemination is undermined by the lack of AIAN leadership. This project is designed to build on and expand the successful Native Children's Research Exchange Scholars (NCRE) program to support the development of AIAN early career substance abuse researchers. NCRE Scholars began in 2012 on the foundation of the NCRE network of researchers engaged in research with AIAN children and adolescents. The NCRE network provides a platform for connecting graduate students, post-docs, and junior faculty to senior research mentors who provide substantive mentoring and career development support. The NCRE conferences attended by this network offer a forum for sharing information and further building collaborative relationships. The proposed project will support the development of the next generation of AIAN substance abuse and addiction scientists by: (1) sustaining the NCRE Scholars program to support 10 additional Scholars in 5 Cohorts of 2 Scholars each; (2) retaining the fundamental components of the successful NCRE Scholars program, continuing to provide intensive mentoring to small cohorts of Scholars in connection to the NCRE network through the creation and implementation of Tailored Career Development Plans and support of writing objectives; (3) expanding the experiences for NCRE Scholars with the guidance of a Scholars Advisory board and by developing a Grantwriting Workshop to be delivered in conjunction with NCRE Conferences and a structured curriculum in the Responsible Conduct of Research with AIAN Communities; and (4) integrating a small NCRE student mentoring effort with the NCRE Scholars program to enhance engagement of potential researchers earlier in the educational pipeline (NCRE stars program; Students Thinking About Research careerS).