AI Reservation-based FASD Prevention

描述（由申请人提供）：该项目的目的是减少保留社区中怀孕的AI/AN妇女和育龄妇女的饮酒，以降低胎儿酒精谱系障碍（FASD）的发生率，该疾病在AI/AN人群中更常见。为实现这一目标，提出了三个具体目标：1）加深我们对孕妇/育龄妇女饮酒的理解，以及这种理解对保留地社区预防实践的影响; 2）利用CBPR方法，评估基于证据的FASD预防干预措施在该保留地社区的相关性、可行性和可持续性; 3）选择一种预防性干预措施进行小规模的适应性和试点测试，为涉及同一部落人口的多个保留社区的更大规模的随机对照试验做准备。该研究小组将与当地AI/AN保留社区合作开展这项工作，使用基于社区的调查研究（CBPR）方法作为完成所有工作的指南，包括社区咨询委员会（CAB）的参与。SA 1将涉及使用焦点小组和定性分析结果，这些结果将与CAB以及一组关于FASD预防的国家专家一起审查，以选择有希望的现有循证预防干预措施。将对选定的预防性干预措施进行调整，使其在该部落社区内具有相关性（例如文化上）、可行性和可持续性。调整后的干预措施将在一小部分妇女（n=10-20）中试行。在试点以及在此试点工作基础上进行的任何其他调整之后，该团队将与该社区和其他部落相关社区合作，将这项工作扩大到全面的预防性干预试验。该项目承诺解决一个重要的健康差距（FASD）在一个服务不足的群体（AI/AN），经历了多个健康差距相对于一般美国和其他种族群体的人口。如果成功，该项目将减少禽流感/AN人群在FASD方面的疾病负担。公共卫生相关性：该项目承诺解决一个重要的健康差距（胎儿酒精谱系障碍; FASD）在一个服务不足的群体（美国印第安人和阿拉斯加原住民; AI/AN），经历了多个健康差距相对于一般美国和其他种族群体的人口。如果成功，该项目将减少禽流感/AN人群在FASD方面的疾病负担。

DESCRIPTION (provided by applicant): The purpose of this project is to reduce drinking among pregnant AI/AN women and women of childbearing age in a reservation community, in an effort to reduce the rate of Fetal Alcohol Spectrum Disorders (FASD), which occurs more frequently in AI/AN populations. Three specific aims are proposed to achieve this goal: 1) to deepen our understanding of drinking among pregnant women/women of childbearing age and the implications of this understanding for prevention practices in a reservation community; 2) utilizing a CBPR approach, assess the relevance, feasibility, and sustainability of evidence-based FASD preventive interventions in this reservation community; and 3) select one preventive intervention for adaptation and pilot testing on a small scale in preparation for a larger randomized control trial involving multiple reservation communities of the same tribal population. The research group will partner with a local AI/AN reservation community to conduct this work, using Community-Based Participatory Research (CBPR) methods as a guide for all work to be completed, including the involvement of a Community Advisory Board (CAB). SA1 will involve the use of focus groups and a qualitative analysis of findings which will be reviewed with the CAB, as well as a group of national experts on FASD prevention, in the service of selecting a promising existing evidence-based preventive intervention. Adaptations will be made to the chosen preventive intervention to make it relevant (e.g. culturally), feasible, and sustainable within this tribal community. The adapted intervention will be piloted with a small sample of women (n=10-20). Following the pilot, and any additional adaptations based on this pilot work, the team will work with this community and other tribally related communities to expand this work to a full-scale trial of the preventive intervention. This project promises to address an important health disparity (FASD) in an underserved group (AI/AN) that experiences multiple health disparities relative to the general U.S. and other racial group populations. If successful, this project will reduce the burden of disease borne by AI/AN populations with respect to FASD. PUBLIC HEALTH RELEVANCE: This project promises to address an important health disparity (Fetal Alcohol Spectrum Disorders; FASD) in an underserved group (American Indian and Alaska Natives; AI/AN) that experiences multiple health disparities relative to the general U.S. and other racial group populations. If successful, this project will reduce the burden of disease borne by AI/AN populations with respect to FASD.