Neuronal Substrate of Choice in the Rat Whisker System

大鼠晶须系统中神经元基质的选择

• 批准号: nhmrc : 1028670
• 负责人: A/Pr Ehsan Arabzadeh
• 金额: $ 27.06万
• 依托单位: Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/neuronal-substrate-choice-rat-whisker/110657
• 关键词: Neuronal; Substrate; Choice; Rat; Whisker

Humans and other animals can optimise their goal-directed behaviour by linking stimuli or actions to consequent positive and negative rewards. How does an animal generate such associations, and make decisions in the natural environment where the associations are often uncertain, at times contradictory, and continuously changing? This project uses rat whisker system as an animal model to identify the neuronal basis of perceptual decision making and the role of context.

人类和其他动物可以通过将刺激或行动与随后的积极和消极奖励联系起来来优化其目标导向的行为。动物如何产生这样的联想，并在自然环境中做出决定，在自然环境中，这些联想常常是不确定的，有时是矛盾的，而且不断变化的？该项目使用大鼠胡须系统作为动物模型，以确定感知决策的神经元基础和环境的作用。