Core B: Bioengineering Core

核心B：生物工程核心

• 批准号: 10019392
• 负责人: Braden Fleming
• 金额: $ 26.55万
• 依托单位: RHODE ISLAND HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-01 至 2022-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10019392
• 关键词: Atomic Force Microscopy; Biomechanics; Biomedical Engineering; Biotechnology; Centers of Research Excellence; Clinical; Communities; Community Hospitals; Consultations; Data; Development; Equipment; Foundations; Health; Hospitals; Human Resources; Image; Industry; Laboratories; Magnetic Resonance Imaging; Materials Testing; Motion; Musculoskeletal; Musculoskeletal Diseases; New England; Orthopedics; Phase; Pilot Projects; Play; Publications; Research Personnel; Resources; Rhode Island; Roentgen Rays; Scientist; Services; Study models; Testing; Tissues; Translational Research; Translations; Universities; University Hospitals; Work; design; in vivo; medical schools; microCT; novel therapeutic intervention; prevent; repaired; skeletal

Core B: Bioengineering Core 7. Project Summary/Abstract The overall objectives of the Bioengineering Core are 1) to provide the biomechanical expertise and resources to the university and hospital communities and establish a regional presence in New England, and 2) to become a financially independent center in Phase III. The Bioengineering Core was initially founded by combining the expertise and equipment available in the Bioengineering Laboratories of the Department of Orthopaedics at Rhode Island Hospital, the Atomic Force Microscopy Laboratory in the Division of Biomedical Engineering at Brown University, and the biomechanical testing facility of the Rhode Island Hospital Orthopaedic Foundation (RIHOF). Since the inception of the Bioengineering Core, the number of projects utilizing the Core has increased each year, and the resources available through the core have been expanded through the acquisition and development of new equipment. The Bioengineering Core is a state-of- the-art facility that will continue to be available to all of COBRE projects, and to researchers in the hospital and university communities, both locally and nationally. The Core has an array of equipment that will allow material testing of musculoskeletal tissues, motion analysis (standard motion capture and biplane videoradiograph) and imaging (X-ray, microCT, CT and MRI). To date, 58 publications have resulted from studies that utilized the personnel and resources of the Bioengineering Core that range in scale from bench top laboratory work to in vivo assessment of whole body motion. The projects presented in these publications demonstrate that the Core will continue to play a key role in supporting regional projects and to facilitate the translation of novel therapeutic approaches to prevent and/or treat musculoskeletal disease.

核心B：生物工程核心 7.项目总结/摘要 生物工程核心的总体目标是：1）提供生物力学专业知识， 资源的大学和医院社区，并建立一个新的区域存在 2）在第三阶段成为财政独立的中心。生物工程的核心是 最初是通过结合生物工程实验室的专业知识和设备建立的， 罗得岛医院骨科，分部原子力显微镜实验室 布朗大学生物医学工程系和罗得岛的生物力学测试设施 医院骨科基金会。自生物工程核心成立以来， 利用核心资源的项目每年都在增加，通过核心资源提供的资源也在增加。 通过购买和开发新设备扩大。生物工程的核心是一个国家的- 最先进的设施，将继续提供给所有的COBRE项目，并在医院和研究人员 大学社区，包括当地和全国。内核有一系列设备可以让物质 肌肉骨骼组织测试、运动分析（标准运动捕捉和双平面视频放射成像），以及 成像（X射线、微型CT、CT和MRI）。迄今为止，已有58篇出版物来自使用 生物工程核心的人员和资源，范围从实验室工作到 全身运动的体内评估。这些出版物中介绍的项目表明， 核心将继续在支持区域项目和促进小说翻译方面发挥关键作用。 预防和/或治疗肌肉骨骼疾病的治疗方法。