Human Subjects Clinical Core Component 2

项目总结 临床核心中心是一个理想的脑损伤研究中心，拥有最先进的神经心理学， 用于脑损伤功能检测的电生理和神经影像仪器及新型仪器 用于研究脑损伤恢复和修复的神经刺激技术。临床核心是 协作、跨学科的环境，提供研究设计和方法方面的专家指导，关键 支持患者招募、数据收集和管理，以确保数据的可靠性和可重复性 结果，并使用良好的临床实践协助法规遵从性。总体而言，这个平台拥有 在北卡罗来纳大学释放了脑损伤研究的潜力，以改善脑损伤患者的结果。 临床核心成功地推动了我们年轻、有前途的研究人员进行独立研究 基金状况，现已成为应用创新神经调节研究的全国领先者 治疗靶向和改变神经性疾病患者特定神经回路的方法 条件。总体而言，第二阶段的核心目标是在第一阶段成就的基础上再接再厉并继续 我们朝着成为一家独立于创意资金的自给自足的研究企业的方向迈进。我们 将继续提供资源和专业知识来支持创新研究，这将加速 项目队列带来了独立的资金，并扩大了我们的新临床和已建立临床的数量 调查人员作为核心用户，按服务收费。核心将继续投资于新的仪器设备， 改进我们的招聘方法，确保跟踪并向人类科目系统(HSS)和 临床试验.gov。临床核心将继续促进临床和临床之间的多学科合作 UNM内的临床前研究人员，并与州和地区机构接触，以开发新的 合作伙伴关系和培训合作，因为我们寻求成为大脑研究的领先资源中心。 通过这些努力，我们将寻找治疗大脑和行为疾病的新干预措施，这些干预措施将导致 改善脑损伤患者及其家人的预后。

PROJECT SUMMARY The Clinical Core is an ideally-situated brain injury research hub, with state-of-the-science neuropsychological, electrophysiological and neuroimaging instrumentation to measure brain injury function and novel neurostimulation technologies for studies of brain injury recovery and repair. The Clinical Core is a collaborative, interdisciplinary environment providing expert guidance in research design and methods, critical support for patient recruitment, data collection and management to ensure reliability and reproducibility of results, and assistance with regulatory compliance using Good Clinical Practices. Collectively, this platform has unleashed the brain injury research potential at UNM to improve the outcomes of individuals with brain injuries. The Clinical Core has succeeded in propelling our young, promising investigators to independent research funding status and is now established as a national leader in research applying innovative neuromodulation approaches to therapeutically target and alter specific neural circuitries in individuals with neurological conditions. Overall, the goal of the Core in Phase II is to build on our Phase I accomplishments and continue our progress towards becoming a self-sustaining research enterprise that is independent of IDeA funding. We will continue to provide the resources and expertise to support innovative research that will accelerate a new cohort of Project Leads to independent funding and expand our mass of new and established clinical investigators as Core users on a fee for service basis. The Core will continue to invest in new instrumentation, advance our recruiting approaches and ensure tracking and reporting to Human Subjects System (HSS) and Clinical Trials.gov. The Clinical Core will continue to foster multidisciplinary collaboration between clinical and preclinical investigators within UNM and reach out to state and regional institutions to develop new partnerships and training collaborations as we seek to be a leading resource center for brain research. Through these efforts we will search for new interventions for brain and behavioral illnesses that will lead to improved outcomes for individuals with brain injury and their families.