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Overdose Risk Management and Compensation in the Era of Naloxone

Overdose Risk Management and Compensation in the Era of Naloxone
纳洛酮时代的过量风险管理和补偿
批准号:
10004601
负责人:
Alexander S Bennett
金额:
$74.79万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2019
资助国家:
美国
项目状态:
已结题
起止时间:
2019-06-01 至 2023-05-31
关键词:
AddressAdultAgeAlcohol or Other Drugs useAreaAttitudeAwarenessBehaviorBehavior TherapyBehavioralCessation of lifeCitiesCost SavingsData CollectionDevelopmentDiagnosisDrug usageEducationEducation and OutreachEducational CurriculumEmergency Medical TechniciansEmergency SituationEnrollmentEnsureEthicsEthnic OriginEthnographyEventExposure toFailureFemaleFinancial compensationFoundationsFundingFutureGeographic stateHealthHealth BenefitHeartHeroinHuman ResourcesIndividualInjecting drug userIntentionInterventionInvestigationKnowledgeLearningLifeMeasurableMental HealthMethodsMilitary PersonnelNaloxoneNaloxone TrainingNational Institute of Drug AbuseNeighborhoodsNew York CityOpiate AddictionOpioidOpioid abuserOverdoseParticipantPatient Self-ReportPatternPerceptionPharmaceutical PreparationsPharmacologic SubstancePharmacy facilityPlayPolicePrevention educationPrevention programProcessPsychosocial FactorPublic DomainsPublic HealthPublished CommentRecording of previous eventsReportingResearchRespondentRiskRisk BehaviorsRisk ManagementRisk ReductionRisk-TakingRoleSamplingSan FranciscoSeveritiesStatutes and LawsSubgroupSurveysTestingText MessagingTimeTrainingTraining ProgramsTreatment/Psychosocial EffectsUnited StatesUrsidae FamilyVeteransbasecareercatalystcostdesignexperiencefirst responderheroin usehigh risk behaviorillicit opioidinsightinterestmalenewsopioid epidemicopioid overdoseopioid useopioid use disorderopioid useroutreachoverdose preventionoverdose riskprescription opioidprescription opioid misusepsychosocialpublic health relevancerecruitresponsesafety netsocialsocial culturesocial structuresuccesstooluptakewillingness

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英文摘要
ABSTRACT As alarming rates of opioid-related overdose have come to dominate the national dialogue on drug-related harms, the overdose reversal medication naloxone has expanded from the confines of emergency medical personnel to the public domain. The rapid legislative response of many US states to the current epidemic of opioid dependence and overdose has resulted in widespread initiatives to provide naloxone not only to professional first-responders, but also to active opioid users. These initiatives have already demonstrated their worth and are responsible for thousands of overdose reversals and lives saved. To date, however, two important topic areas that bear on the ongoing success of overdose education and naloxone distribution efforts remain unexplored. The first concerns potential gaps in knowledge about and access to naloxone among people who use opioids but are not connected to opioid overdose prevention programs where the bulk of outreach is conducted. The second concerns the largely unexplored behavioral and psychosocial effects of surviving or “reversing” an overdose in which naloxone was administered and of simply having naloxone present while engaging in overdose risk behaviors. Preliminary evidence suggests that these impacts may involve different trajectories depending on individual and social-structural factors. For some, reversing an overdose has been reported to empower individuals to maintain safe opioid use practices. For others, naloxone provision has been met with a self-reported intention to use more opioids. Why naloxone provokes such widely varying responses, and for whom it produces the most robust health benefits, remain critically unexamined questions. To address these public health concerns, this study responds to the current NIDA and FDA mandate for “additional formative and implementation studies of naloxone distribution and overdose intervention in field settings, particularly for prescription opioid abusers.” Using a mixed-method approach designed to yield richly contextualized findings, the proposed study will recruit a sample of 600 people who use illicit opioids in New York City to: a) learn which subgroups of illicit opioid users have been trained in naloxone, used it, or had it used on them, and why some continue to refuse training; b) identify the risk-behavior impacts of using naloxone, surviving an overdose because of naloxone, or having naloxone and a trained overdose responder present when using illicit opioids; and, c) illuminate opioid users’ own perspectives on overdose risk management and naloxone’s role within that, and identify social-structural and psychosocial factors underlying both positive and negative changes in overdose risk behavior. Taken together, these objectives have the power to inform the tailoring and targeting of existing outreach and education strategies and to guide the development of new intervention tools for opioid users whose exposure to naloxone and overdose events may represent powerful turning- points in their drug use careers and catalysts for positive behavioral change.
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Evaluation of a community-based education, navigation, and support (CENS) intervention to reduce opioid-related harms among military veterans
  • 批准号:
    10493264
  • 项目类别:
  • 资助金额:
    $69.35万
  • 财政年份:
    2021
  • 负责人:
    Alexander S Bennett
  • 依托单位:
Evaluation of a community-based education, navigation, and support (CENS) intervention to reduce opioid-related harms among military veterans
  • 批准号:
    10666577
  • 项目类别:
  • 资助金额:
    $68.11万
  • 财政年份:
    2021
  • 负责人:
    Alexander S Bennett
  • 依托单位:
Evaluation of a community-based education, navigation, and support (CENS) intervention to reduce opioid-related harms among military veterans
  • 批准号:
    10298478
  • 项目类别:
  • 资助金额:
    $71.58万
  • 财政年份:
    2021
  • 负责人:
    Alexander S Bennett
  • 依托单位:
Overdose Risk Management and Compensation in the Era of Naloxone
  • 批准号:
    10623371
  • 项目类别:
  • 资助金额:
    $12.99万
  • 财政年份:
    2019
  • 负责人:
    Alexander S Bennett
  • 依托单位:
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