Patient-Centered Strategies to Reduce Disparities in Access to Kidney Transplantation

摘要 坦加拉湾Purnell博士，公共卫生硕士，约翰霍普金斯大学外科系第二年助理教授。 霍普金斯医学院与约翰霍普金斯大学流行病学系的联合教员任命 霍普金斯布隆伯格公共卫生学院。她寻求这个指导研究科学家的发展（K01） 以患者为中心的成果研究奖（PCOR），以支持她建立自己的长期职业目标 作为一名卫生服务研究人员和社会流行病学家， 实施以患者为中心的干预措施，以实现公平获得肾移植。在此 奖，她将追求严格的研究和教学计划，包括先进的课程，研讨会， 并指导研究，这将大大提高她在发展患者和患者参与方面的技能。 干预措施，以解决终末期肾移植患者获得肾移植的差异 终末期肾病（ESRD）是一种导致临床和患者报告结局不良的疾病。她的研究和 职业目标与AHRQ的使命密切相关， 设计和实施变革和组织振兴方案，以改善优先人群的临床和患者报告结局。 在她的研究计划中，Purnell博士将描述患者和社区压力源的关联， 在完成KT评价过程（目标1）方面存在差距。她还将让病人，家庭成员， 健康教育专家和临床提供者在发展（目标2）和试点测试（目标3）的病人， 以KT评估过程为中心的教育材料。这些研究是基于 直接反馈患者对KT过程未满足的担忧，并为未来的 研究，以测试以病人为中心的决策支持在减少获得KT的差距的有效性。 在她的教学计划中，她将接受密集的培训，从事翻译研究， 定性研究方法，以患者为中心的干预措施的发展，以及设计和实施 在约翰霍普金斯流行病学研究的丰富训练环境中进行的随机临床试验 约翰霍普金斯消除心血管健康差异中心器官移植小组 霍普金斯卫生服务和成果研究中心和韦尔奇预防中心， 流行病学和临床研究。她将获得Dorry Segev，MD PhD和 丽莎A.库珀，医学博士MPH和指导教师顾问和患者利益相关者的示范团队 谁是致力于她的成功，并将支持这项申请的研究和教学目标。

ABSTRACT Tanjala S. Purnell, PhD MPH is a second-year Assistant Professor in the Department of Surgery at the Johns Hopkins School of Medicine with a joint faculty appointment in the Department of Epidemiology at the Johns Hopkins Bloomberg School of Public Health. She seeks this Mentored Research Scientist Development (K01) Award in patient-centered outcomes research (PCOR) to support her long-term career goal of establishing her independence as a health services researcher and social epidemiologist dedicated to identifying and implementing patient-centered interventions to achieve equity in access to kidney transplantation. During this award, she will pursue a rigorous research and didactic program, including advanced coursework, seminars, and mentored research that will substantially build her skills in developing patient- and stakeholder-engaged interventions to address disparities in access to kidney transplantation for patients with end stage renal disease (ESRD), a condition that results in poor clinical and patient-reported outcomes. Her research and career objectives are closely aligned with the AHRQ's mission of engaging patients and stakeholders in the design and conduct of PCOR to improve clinical and patient-reported outcomes for priority populations. In her research program, Dr. Purnell will characterize the associations of patient and community stressors with disparities in completion of the KT evaluation process (Aim 1). She will also engage patients, family members, health education experts, and clinical providers in the development (Aim 2) and pilot testing (Aim 3) of patient- centered educational materials about the KT evaluation process. These studies were developed based upon direct patient feedback regarding unmet concerns about the KT process and will lay the foundation for future research to test the effectiveness of patient-centered decision support in reducing disparities in access to KT. In her didactic program, she will undergo intensive training in stakeholder-engaged and translational research, qualitative research methods, development of patient-centered interventions, and the design and conduct of randomized clinical trials within the rich training environments of the Johns Hopkins Epidemiology Research Group in Organ Transplantation, Johns Hopkins Center to Eliminate Cardiovascular Health Disparities, Johns Hopkins Center for Health Services and Outcomes Research, and the Welch Center for Prevention, Epidemiology, and Clinical Research. She will receive primary mentorship from Dorry Segev, MD PhD and Lisa A. Cooper, MD MPH and guidance from an exemplary team of faculty advisors and patient stakeholders who are committed to her success and will support the research and didactic goals of this application.