TASK ORDER 05. NON-CLINICAL ADME STUDIES. TASK ORDER POP: 07/10/2019-07/09/2020. N01DA-16-8931.PURPOSE: THE SCOPE OF THIS TASK ORDER IS A) DEVELOP AN ABBREVIATED LC-MS/MS ASSAY FOR ALMITRINE IN RAT

任务单 05。非临床 ADME 研究。

• 批准号: 10042663
• 负责人: Lalitha Iyer
• 金额: $ 11.02万
• 依托单位: SRI INTERNATIONAL
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-19 至 2021-09-18
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10042663
• 关键词: ADME Study; Biological Assay; Blood specimen; Contractor; Female; Hour; Intramuscular Injections; Plasma; Rattus; Sampling; Site; Validation; male

Task Order Description: The scope of this task order is a) develop an abbreviated LC-MS/MS assay for almitrine in rat plasma; b) conduct a PK study of almitrine in male and female rats; c) assay the plasma samples for almitrine.

任务订单描述：本任务订单的范围是a）开发简化的LC-MS/MS测定 B）在雄性和雌性大鼠中进行阿米三嗪的PK研究; c）测定 血浆样本里的阿米三嗪