A direct-reading dosimeter badge for monitoring personal exposure to Polycyclic Aromatic Hydrocarbons (PAHs)
用于监测个人接触多环芳烃 (PAH) 的直读剂量计徽章
基本信息
- 批准号:10010384
- 负责人:
- 金额:$ 13.83万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-09-01 至 2021-02-28
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Project Summary
Through this SBIR project, we aim to develop new methods and technologies for
monitoring personal exposure to polycyclic aromatic hydrocarbons (PAHs). Because PAHs cause
DNA damage that may initiate cancer, these compounds pose considerable risk to human health.
Chronic exposure to PAHs in the workplace has been associated with increased risk of cancer for
firefighters, road construction workers, roofers and vehicle operators. To identify and assess
worker exposure to airborne PAHs, industrial hygienists utilize sorbent tubes. However, this
method has significant disadvantages including high-cost, burdensome sampling and handling,
low accuracy and delayed reporting due to required analysis by an external laboratory. Thus, there
exist an unmet need for new methods for monitoring exposure to PAHs.
This project aims to develop simple, low-cost, wearable dosimeters sampling badges that
provide real-time and accurate monitoring of exposure to airborne PAHs. This work builds on
exciting preliminary results that demonstrate that films of liquid crystals (LC) exhibit an abrupt
optical transition when exposed to PAHs, but not when exposed to other gaseous chemicals. In
Phase I, we will use hypothesis-based testing to develop a better understanding of materials and
design considerations to guide the development of LC-based dosimeters for measuring exposure
to PAHs. We aim to (i) understand the material properties that influence the response of LC films
to PAHs with the goal of optimizing sensitivity, and (ii) identify dosimeter configurations that
enable quantitative measurements of the concentration of PAHs in air. The outcomes of this work
will provide design principles for fabricating dosimeter sampling badges for quantitative
characterization of exposure to PAHs in the workplace. More broadly, the tools and methods
developed through these efforts will enable new assessments on worker exposures to PAHs, and
this new knowledge may lead to actions that reduce occupational cancer and other adverse health
outcomes, and create safer workplaces. Thus, the goals of this SBIR project are well alight with
the NIOSH Priority Goals for Extramural Research for 2019-2023.
项目总结
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Marco A Bedolla Pantoja其他文献
Marco A Bedolla Pantoja的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Marco A Bedolla Pantoja', 18)}}的其他基金
Wearable Multi-Gas Technologies for Monitoring Personal Air Quality
用于监测个人空气质量的可穿戴多气体技术
- 批准号:
10383219 - 财政年份:2022
- 资助金额:
$ 13.83万 - 项目类别:
A direct-reading dosimeter badge for monitoring personal exposure to Polycyclic Aromatic Hydrocarbons (PAHs)
用于监测个人接触多环芳烃 (PAH) 的直读剂量计徽章
- 批准号:
10263860 - 财政年份:2020
- 资助金额:
$ 13.83万 - 项目类别:
相似国自然基金
精子发生中mRNA下游开放阅读框(downstream Open Reading Frame,dORF)的功能研究
- 批准号:
- 批准年份:2022
- 资助金额:54 万元
- 项目类别:面上项目
相似海外基金
The mechanism of CELF1 upregulation and its role in the pathogenesis of Myotonic Dystrophy Type 1
CELF1上调机制及其在强直性肌营养不良1型发病机制中的作用
- 批准号:
10752274 - 财政年份:2024
- 资助金额:
$ 13.83万 - 项目类别:
SBIR Phase II: Computer-based co-reading for students with reading disabilities
SBIR 第二阶段:为有阅读障碍的学生提供基于计算机的共同阅读
- 批准号:
2321439 - 财政年份:2024
- 资助金额:
$ 13.83万 - 项目类别:
Cooperative Agreement
HSI Implementation and Evaluation Project: Scaling and Extending Exploratory Reading Groups to Strengthen Computing Pathways
HSI 实施和评估项目:扩大和扩展探索性阅读小组以加强计算途径
- 批准号:
2414332 - 财政年份:2024
- 资助金额:
$ 13.83万 - 项目类别:
Continuing Grant
I-Corps: Artificially Intelligent Dialogic Reading Aid
I-Corps:人工智能对话阅读辅助工具
- 批准号:
2349210 - 财政年份:2024
- 资助金额:
$ 13.83万 - 项目类别:
Standard Grant
An Eye-Tracking Study: Exploring Integrated Reading Tasks in the New Format of the English Common Test for Japanese University Admissions
眼动追踪研究:探索日本大学入学英语通用考试新形式中的综合阅读任务
- 批准号:
24K04032 - 财政年份:2024
- 资助金额:
$ 13.83万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
International Institutional Awards Tranche 2 Reading
国际机构奖第二期阅读
- 批准号:
BB/Z514615/1 - 财政年份:2024
- 资助金额:
$ 13.83万 - 项目类别:
Research Grant
Readingに関する自律的英語学習メカニズムの解明
与阅读相关的英语自主学习机制阐释
- 批准号:
24K04152 - 财政年份:2024
- 资助金额:
$ 13.83万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Digital building blocks of elementary school foreign language reading motivation
小学外语阅读动机的数字积木
- 批准号:
23K25344 - 财政年份:2024
- 资助金额:
$ 13.83万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
Affective Computing Models: from Facial Expression to Mind-Reading
情感计算模型:从面部表情到读心术
- 批准号:
EP/Y03726X/1 - 财政年份:2024
- 资助金额:
$ 13.83万 - 项目类别:
Research Grant
University of Reading and Starlight Xpress Limited KTP 23_24 R1
雷丁大学和 Starlight Xpress Limited KTP 23_24 R1
- 批准号:
10070106 - 财政年份:2024
- 资助金额:
$ 13.83万 - 项目类别:
Knowledge Transfer Partnership