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Drone-Delivered Naloxone System for Opioid Overdose Treatment

Drone-Delivered Naloxone System for Opioid Overdose Treatment
无人机交付的纳洛酮系统用于阿片类药物过量治疗
批准号:
10011978
负责人:
Joseph P ORNATO
金额:
$22.47万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2020
资助国家:
美国
项目状态:
已结题
起止时间:
2020-07-01 至 2021-06-30

项目摘要

项目成果

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中文摘要
翻译
项目主管/首席研究员(最后,第一,中):Ornato, Joseph, Pasquale
英文摘要
Program Director/Principal Investigator (Last, First, Middle): Ornato, Joseph, Pasquale Summary One hundred thirty Americans die from an opioid overdose (OD) daily. The key to improving this survival is the timely delivery of the antidote naloxone. Current US Emergency Medical Services (EMS) systems are often unable to deliver the life-saving drug fast enough manner to save the victim’s life. Our uniquely-qualified team (Virginia UAS, LLC commercial drone pilot training instructors; a Virginia Commonwealth University (VCU) faculty physician EMS medical director/jet and commercial drone pilot with extensive experience leading high-impact, multicenter, prehospital NIH clinical trials; and VCU engineers with experience in development and commercialization of drone hardware and software) has developed a novel prototype drone system that is interfaced to Richmond’s 9-1-1 dispatch computer. The system automatically loads a 9-1-1 bystander caller’s GPS phone location into a drone and launches it to the scene of an opioid OD carrying a lightweight, removable, patent-pending, real-time audio/video package (COMMRx) containing naloxone nasal spray. Just five drones in the City of Richmond could ensure delivery of the naloxone package to bystanders in ≤2 min as EMS first responders begin racing to the scene. Trained 9-1-1 pilot dispatchers would direct the bystander to remove COMMRx from the drone, take it to the victim, and administer the naloxone spray long before first responders can physically reach the victim. This Phase I project proposes to: 1) finalize the system customization; 2) train/FAA-certify seven 9-1-1 dispatchers drone pilots; and 3) perform realistic simulation testing of the system to guide design of a Phase II clinical trial to take place in Richmond, Henrico/Chesterfield counties, and Roanoke, VA. This novel system developed and executed by a uniquely qualified team shifts the paradigm of prehospital emergency care delivery by empowering and directing laypersons to initiate time-dependent, life-saving treatment to opioid OD victims long before EMS personnel can physically treat the patient. Our commercial goal is to expand our flight school business to provide similar capability throughout the 5,783 9-1-1 centers nationally. OMB No. 0925-0001/0002 (Rev. 01/18 Approved Through 03/31/2020) Page Continuation Format Page
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Neurological Emergencies Treatment Trials (NETT) Network Clinical Site Hubs
  • 批准号:
    7924230
  • 项目类别:
  • 资助金额:
    $19.41万
  • 财政年份:
    2007
  • 负责人:
    Joseph P ORNATO
  • 依托单位:
Neurological Emergencies Treatment Trials (NETT) Network Clinical Site Hubs
  • 批准号:
    7256608
  • 项目类别:
  • 资助金额:
    $37.25万
  • 财政年份:
    2007
  • 负责人:
    Joseph P ORNATO
  • 依托单位:
Neurological Emergencies Treatment Trials (NETT) Network Clinical Site Hubs
  • 批准号:
    7676777
  • 项目类别:
  • 资助金额:
    $19.41万
  • 财政年份:
    2007
  • 负责人:
    Joseph P ORNATO
  • 依托单位:
Neurological Emergencies Treatment Trials (NETT) Network Clinical Site Hubs
  • 批准号:
    7503420
  • 项目类别:
  • 资助金额:
    $19.41万
  • 财政年份:
    2007
  • 负责人:
    Joseph P ORNATO
  • 依托单位:
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