权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Opioid Treatment Adoption in Primary Care Settings: Barriers and Facilitators to Implementation

初级保健机构采用阿片类药物治疗：实施的障碍和促进因素

基本信息

批准号：
10041254
负责人：
Courtney R. Yarbrough
金额：
$ 17.88万
依托单位：
EMORY UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-08-01 至 2025-07-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10041254
关键词：
Abstinence Accident and Emergency department Address Adopted Adoption American Area Buprenorphine Caring Case Study Characteristics Clinical Communities Community Health Systems Country County Data Set Diffusion Diffusion of Innovation Disease remission Drug Prescriptions Effectiveness Ethnic Origin Evidence based practice Formulation Foundations Future Geography Goals Health Personnel Health Services Accessibility Incentives Income Individual Influentials Interview Knowledge Lead Maintenance Therapy Measures Medicine Mentored Research Scientist Development Award Mentors Mentorship Methadone Methods Modeling Naltrexone National Institute of Drug Abuse Opioid Outcome Overdose Pain Patient Care Patients Pharmaceutical Preparations Pharmacists Pharmacotherapy Physicians Policies Population Portraits Prevalence Primary Health Care Process Provider Public Health Public Health Schools Qualitative Methods Race Recommendation Regulation Reporting Research Research Personnel Resources Rural Sales Socioeconomic Status Structure Subgroup Substance Use Disorder System Testing Theoretical model Time Training Treatment outcome Universities Withdrawal Work addiction base care providers design deviant evidence base implementation research implementation science improved improved outcome innovation insight mortality novel novel strategies opioid epidemic opioid mortality opioid use disorder patient-level barriers peer prescription opioid primary care setting professor provider-level barriers psychosocial racial and ethnic resilience rurality skills system-level barriers theories training opportunity waiver

项目摘要

Project Summary/Abstract There are more than 2 million Americans with opioid use disorder (OUD), contributing to unprecedented levels of overdoses and drug-related mortality in the U.S. Several approved medications for OUD (MOUD) are available, and robust evidence shows them to be more effective than abstinence or psychosocial therapy alone in helping individuals achieve and maintain remission. Yet, less than 20% of individuals with OUD receive any MOUD. Buprenorphine maintenance therapy (BMT) holds significant potential to increase access to treatment as the only MOUD available in a primary care setting that does not require patients to endure withdrawal. Fewer than 7% of physicians prescribe the drug, and more than 40% of U.S. counties do not have a BMT provider, with access further restricted in rural and otherwise underserved areas. It seems that provider-, patient-, and system-level barriers are fueling an “implementation chasm” between the evidence-based practice for OUD and its actual delivery. The objective of this application for a NIDA Mentored Research Scientist Development Award (K01) is to support a new assistant professor in the Emory University Rollins School of Public Health to become a national leader in pioneering innovative, multilevel research on how to close this implementation chasm and reduce drug-related harms and inequities in those harms. To that end, this K01 application provides training opportunities in Implementation Science, spatial analysis, qualitative methods, and addiction medicine. The research aims are designed to reinforce these new skills, using mixed methods and a conceptual model derived from Implementation Science (i.e., the Consolidated Framework for Implementation Research and the Diffusion of Innovations theoretical model) to investigate the modifiable barriers and facilitators to BMT adoption in primary care. Aim 1 uses spatial analysis to develop annual, county-level measures of OUD and BMT treatment availability and determine the local correlates of unmet treatment need, both overall and for disparity populations. Aim 2 observes the diffusion of BMT prescribing among primary care providers, measuring the significant predictors of BMT adoption, including individual-, practice-, system-, and community-level factors. Aim 3 will identify “positive deviant” counties—i.e., those with substantial increases in BMT prescribing over time—and conduct in-depth qualitative case studies to determine the processes associated with successful BMT implementation and sustainment, including novel models of care and local adaptations of best practices. These studies will provide actionable recommendations for communities and health systems seeking to increase access to evidence-based care for OUD. The protected time, resources, and mentorship available through this K01 award will enable Dr. Yarbrough to emerge as an independent and leading researcher in substance use disorders and Implementation Science who will help close the implementation chasm for MOUD treatments and improve outcomes for opioid use disorder patients.

项目总结/文摘