2020 Drug Metabolism Gordon Research Conference and Seminar

2020年药物代谢戈登研究会议暨研讨会

• 批准号: 10063328
• 负责人: JAMES STEVEN LEEDER
• 金额: $ 1万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-05 至 2022-09-04
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10063328
• 关键词: Academia; Address; Analytical Chemistry; Anniversary; Atmosphere; Big Data; CYP2D6 gene; Career Choice; Cells; Chemistry; Clinical; Clinical Pharmacology; Clustered Regularly Interspaced Short Palindromic Repeats; Collaborations; Computer Models; Cytochrome P450; Data; Development; Discipline; Dose; Drug Industry; Drug Kinetics; Environment; Enzymatic Biochemistry; Exposure to; Future; Genetic Polymorphism; Growth; Hearing; Hour; In Vitro; Individual; Industry; Knowledge; Learning; Mass Spectrum Analysis; Membrane Transport Proteins; Mentors; Mentorship; Metabolism; Microfluidics; Modeling; Molecular Biology; Nature; Oral; Outcome; Patients; Pharmaceutical Preparations; Pharmacodynamics; Pharmacology and Toxicology; Population; Postdoctoral Fellow; Precision therapeutics; Process; Property; Recommendation; Research; Research Personnel; Role; Science; Scientific Advances and Accomplishments; Scientist; Seminal; Techniques; Technology; Testing; Therapeutic Agents; Time; Update; Woman; Work; absorption; career; career development; design; drug development; drug discovery; drug disposition; drug metabolism; experience; graduate student; in vitro activity; in vivo; innovation; insight; interest; meetings; microbiome; novel; novel therapeutics; patient population; posters; precision medicine; reconstitution; stem cells; symposium; therapeutic siRNA

Project Summary The 50th Drug Metabolism Gordon Research Conference (GRC) in 2020 will highlightunpublished, cutting-edge research patients as unique individuals, rather than populations, as a preparatory step to delivering precision therapeutics. that celebrates advances in the field over the past 50 years, with an emphasis on An essential component of the knowledge to be acquired is a clear understanding of the absorption, distribution, metabolism, and elimination (ADME) properties of the drug. The 2020 conference will include a keynote presentation on the integration of drug metabolism science and big data to inform precision medicine, and in celebration of the 50th anniversary the scientific sessions will provide cutting-edge contemporary updates on topics discussed at the first Drug Metabolism GRC, such as drug metabolism by the microbiome, mechanisms of drug metabolism and extrapolation of in vitro data to drug metabolism in vivo. Topics, such as membrane transporters, technologies like mass spectrometry and novel therapeutics entities, such as siRNA-based therapeutic agents unknown in 1971 will also be discussed. As expected for GRCs all presentations will include unpublished data, with sessions designed for maximal audience participation and discussion. Attendees are encouraged to submit posters for display at the poster sessions organized by the Vice Chair Dr. Jane Kenny. Posters are viewed during a 2-hour session every day of the conference which provides ample time for interaction. The Wednesday evening session will feature oral presentations by young investigators (graduate students, postdoctoral trainees and early career scientists) selected from the submitted poster abstracts. The conference is collegial and informal in nature, with ample opportunity to discuss unpublished research, make collaborative connections, and develop new ideas. Young investigators have easy access to mentoring from established investigators, as well as during informal career advice discussions planned during the week. There will be a session featuring an open discussion of challenges faced by women in science during the meeting led by two early career women scientists. Overall, the meeting will provide an opportunity for researchers in the ADME field to hear cutting edge science and have in depth discussions with colleagues that will facilitate collaboration, career development and learning.

项目摘要 2020年第50届药物代谢戈登研究会议（GRC）将突出显示 研究患者独特 个人而不是人群，是提供精确治疗的准备步骤。 在过去的50年中，庆祝该领域的进步，重点是 必不可少的 要获得的知识的组成部分是对吸收，分布，代谢， 和消除药物的特性。 2020年会议将包括有关 药物代谢科学和大数据的整合以为精确医学提供信息，并庆祝第50 周年纪念科学会议将在讨论的主题上提供最新的当代更新 第一次药物代谢GRC，例如微生物组的药物代谢，药物代谢的机制和 在体内外推向药物代谢。主题，例如膜转运蛋白，技术 例如质谱和新型治疗实体，例如基于siRNA的治疗剂 1971年也将讨论。如预期的GRCS，所有演示文稿都将包括未发表的数据 专为最大程度的观众参与和讨论而设计。鼓励与会者提交海报 在副主席简·肯尼（Jane Kenny）博士组织的海报会议上展示。在2小时期间查看海报 会议的每一天会议提供充足的互动时间。星期三晚上会议 将由年轻调查员（研究生，博士后学员和早期职业的口头演讲 科学家）从提交的海报摘要中选择。该会议本质上是合作的和非正式的， 有足够的机会讨论未发表的研究，建立协作联系并发展新想法。 年轻的调查人员可以轻松地从已建立的调查人员以及非正式的过程中访问指导 一周内计划的职业建议讨论。会议将进行公开讨论 在两名早期职业女性科学家领导的会议上，妇女在科学领域面临的挑战。全面的， 这次会议将为Adme Field的研究人员提供一个机会，以听取尖端科学的聆听并拥有 与同事的深入讨论，这些讨论将有助于合作，职业发展和学习。