New methods and guidelines for the design, analysis and reporting of cluster-crossover and stepped wedge randomised trials in clinical and public health research

临床和公共卫生研究中聚类交叉和阶梯式楔形随机试验的设计、分析和报告的新方法和指南

• 批准号: nhmrc : GNT1108283
• 负责人: Dr Joanne McKenzie
• 金额: $ 39.13万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/new-methods-guidelines-health-research/1346636
• 关键词: New; methods; guidelines; design; analysis

Cluster crossover and stepped wedge designs have emerged recently as study designs used in clinical and public health research settings. However, despite their use there has been very little methodological assessment of the statistical analysis methods used in current practice. The proposed research will assess the correctness of current methods and will produce a toolkit of state-of-the art, defensible trial design, analysis and reporting methods for the clinical/health researcher.

最近出现了群集交叉和阶梯楔形设计作为临床和公共卫生研究环境中使用的研究设计。然而，尽管使用了统计分析方法，但对目前实践中使用的统计分析方法进行的方法评估很少。拟议的研究将评估当前方法的正确性，并将为临床/健康研究人员提供一个最先进的、可辩护的试验设计、分析和报告方法的工具包。