African-American Social Support Effectiveness Treatment- Partners Alleviating Perinatal Depression (ASSET-PPD)

非裔美国人社会支持有效性治疗 - 缓解围产期抑郁症的伴侣 (ASSET-PPD)

• 批准号: 10058118
• 负责人: Sheehan David Fisher
• 金额: $ 21.9万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-08-27 至 2022-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10058118
• 关键词: Address; African American; Aftercare; American; Anxiety Disorders; Behavior; Behavioral; Breast Feeding; Caring; Caucasians; Clinical; Cognitive; Communication; Couples; Data; Development; Distress; Educational Curriculum; Effectiveness; Emotional; Environment; Evaluation; Family; Fathers; Feedback; Focus Groups; Future; Generations; Housekeeping; Individual; Infant; Intervention; Learning; Manuals; Maternal Behavior; Measures; Mental Depression; Mental Health; Meta-Analysis; Moods; Mothers; Outcome; Parents; Participant; Performance; Perinatal; Postpartum Depression; Postpartum Period; Prevalence; Protocols documentation; Psychiatric therapeutic procedure; Psychotherapy; Randomized; Recording of previous events; Research Project Grants; Resources; Risk; Risk Factors; Self Care; Severities; Social Environment; Social support; Stress; Testing; Theoretical model; Thinking; Training; Treatment Effectiveness; Woman; antepartum depression; base; comparison group; depressive symptoms; design; effective intervention; experience; health care disparity; health care service utilization; high risk; improved; male; maternal depression; maternal risk; maternal stress; novel; perinatal mental health; perinatal period; peripartum depression; post intervention; postpartum outcome; prenatal; prevent; primary outcome; programs; psychoeducation; psychosocial; recruit; secondary outcome; skills; social; stressor; theories; therapy development; treatment comparison; treatment group

Project Summary/Abstract This Exploratory/Developmental Research Grant Program (R21) addresses perinatal depression in African- American (AA) women. AA mothers have a higher risk for perinatal depression than Caucasian women that is attributable to increased socio-environmental stressors. AA women have poor healthcare utilization and compliance with psychiatric treatment compared to Caucasian women. An intervention is required to supplement and support the clinical objectives of the mother’s depression care without requiring the mother’s direct involvement. Fathers are an underutilized resource to reduce the mother’s environmental stress and encourage healthy maternal behaviors. The PI will test the African-American Social Support Effectiveness Treatment- Partners alleviating Perinatal Depression (ASSET-PPD) protocol, a supplemental intervention to maternal perinatal psychiatric treatment. ASSET-PPD will target the fathers’ support of the mothers’ mental health treatment and their active engagement in the family to reduce maternal stress. The ASSET-PPD intervention will be designed to have 4 active modules that address key factors to reduce maternal stress during the prenatal period and 2 postpartum review sessions. ASSET-PPD is designed as individual sessions. The intervention is based on the theoretical models of the stress-generation and cognitive- behavior theories. The modules will be individual sessions constructed to provide training, information, and behavioral assignments to increase fathers’: 1) prenatal and postpartum family involvement; 2) mental health psychoeducation; 3) interparental communication and relationship skills; and 4) balanced division of family tasks. A post-intervention focus group of mothers and fathers will inform the PI of the utility and acceptability of the intervention. In addition, a panel of subject matter experts will be part of an external advisory board to provide feedback on the intervention development. The finalization of the manual will be executed based on the intervention’s performance, and the focus groups’ and advisory board’s feedback. ASSET-PPD will be evaluated in a pilot RCT with 50 cohabitating fathers and AA mothers who will be randomized into the ASSET-PPD intervention or the comparator group. Fathers only will participate in the intervention, and mothers and fathers will complete measures of mental health and parental experiences. Maternal depressive symptoms will be assessed as a primary outcome, and breastfeeding and parent-infant interactions will be assessed as secondary outcomes to inform the utility of the selected measures for a future large-scale RCT. The objective of this protocol is to: 1) assess the acceptability of the intervention to couples; 2) determine the recruitment rate; 3) evaluate the utility of each module’s key components; 4) assess the adequacy of each measure to evaluate the outcomes targeted by the interventions; and 5) determine whether the pilot data warrant a large-scale RCT.

项目总结/摘要 这个探索/发展研究资助计划（R21）解决非洲围产期抑郁症- 美国（AA）女性AA母亲比高加索妇女有更高的围产期抑郁症的风险， 这是由于社会环境压力的增加。AA女性的医疗保健利用率很低， 与白人女性相比，精神科治疗的依从性。需要进行干预， 补充和支持母亲的抑郁症护理的临床目标，而不需要母亲的 直接参与。父亲是一种未充分利用的资源，可以减轻母亲的环境压力， 鼓励健康的母亲行为。PI将测试非裔美国人社会支持的有效性 治疗-减轻围产期抑郁症（ASSET-PPD）协议，一种补充干预措施， 产妇围产期精神病治疗。ASSET-PPD将针对父亲对母亲精神上的支持， 保健治疗和积极参与家庭活动，以减轻产妇压力。 ASSET-PPD干预措施将设计为具有4个活动模块，以解决关键因素， 产前期间的母亲压力和2次产后回顾会议。ASSET-PPD设计为 个别会议。干预是基于压力产生和认知的理论模型， 行为理论这些模块将是单独的课程，旨在提供培训、信息和 行为分配，以增加父亲的：1）产前和产后的家庭参与; 2）心理健康 心理教育; 3）父母之间的沟通和关系技巧;以及4）平衡的家庭分工 任务一个由母亲和父亲组成的干预后焦点小组将告知PI以下方面的效用和可接受性： 干预。此外，一个主题专家小组将成为外部咨询委员会的一部分， 提供有关干预措施发展的反馈。手册的定稿将根据 干预措施的绩效，以及焦点小组和咨询委员会的反馈。 ASSET-PPD将在一项试点RCT中进行评估，该RCT有50名同居父亲和AA母亲， 随机分入ASSET-PPD干预组或对照组。只有父亲才能参加 干预，母亲和父亲将完成心理健康和父母经验的措施。 母亲抑郁症状将作为主要结局进行评估， 交互作用将作为次要结果进行评估，以告知未来所选措施的效用 大规模RCT。本方案的目的是：1）评估干预对夫妇的可接受性; 2)确定招聘率; 3）评估每个模块的关键组成部分的效用; 4）评估 每项措施是否足以评估干预措施所针对的结果;以及5）确定 试验数据保证了大规模RCT。