Validation and Expansion of Established Norms for Measures of Tinnitus Perception

耳鸣感知测量既定规范的验证和扩展

• 批准号: 10112759
• 负责人: JAMES A HENRY
• 金额: --
• 依托单位: PORTLAND VA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-07-01 至 2024-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10112759
• 关键词: Acoustics; Address; Age; Audiology; Categories; Characteristics; Chronic; Clinic; Clinical; Clinical Research; Code; Computers; Custom; Data; Data Analyses; Data Collection; Data Set; Databases; Development; Devices; Ear; Effectiveness; Enrollment; Equipment; Evaluation; Financial compensation; Foundations; Frequencies; Funding; Guidelines; Hearing; Individual; Intervention; Knowledge; Literature; Loudness; Masks; Measurement; Measures; Medical; Methodology; Methods; Participant; Patients; Perception; Performance; Persons; Pitch Perception; Prevalence; Property; Protocols documentation; Psychoacoustics; Psychophysics; Publishing; Questionnaires; Reaction; Reference Standards; Reference Values; Reporting; Reproducibility; Research; Research Personnel; Resources; Services; Sleep disturbances; Stimulus; System; Tablets; Techniques; Testing; Time; Tinnitus; Training; Training Programs; Treatment Protocols; Update; Validation; Veterans; Work; age group; base; clinical application; cohort; design; disability; effective therapy; emotional distress; improved; inclusion criteria; indexing; programs; sound; treatment effect

Our previous work has collected normative data for measures of both tinnitus perception and tinnitus functional effects (reactions). Participants with chronic tinnitus, who were not receiving tinnitus-specific intervention, completed tinnitus psychoacoustic measures and tinnitus questionnaires at 0, 1, 3, and 6 months. Participants were included in each of six age ranges (18-30; 31-40; 41-50; 51-60; 61-70; 70+). These data will contribute to age-specific reference values for the different measures once all data analyses are complete (final participant testing occurred on October 30, 2018). The proposed study will extend and expand this effort by: (1) building on the normative standards database by testing a cohort of new participants; (2) assessing long-term repeatability of tinnitus psychoacoustic measures by obtaining additional longitudinal data from participants recalled from the previous study; (3) developing methodology to evaluate individual pitch-perception ability and providing training as needed; (4) evaluating the effect of pitch training on ability to match tinnitus pitch with greater precision; and (5) continuing development of the tablet-based tinnitus evaluation system (TES) for clinical utility by improving the interface and other performance features, and by creating a rapid assessment program to obtain reliable loudness matches and pitch matches in under 10 minutes. To accomplish these objectives, new participants will be enrolled into two separate cohorts of 150 and 100 individuals (total new enrollment n=250). Both cohorts of new participants will meet the same inclusion criteria as used in the previous study. The 150 new participants will undergo repeated testing at baseline and at 1, 3, and 6 months to replicate testing as done during the previous study. The separate cohort of 100 new participants will be enrolled to evaluate a training program for pitch matching. Of these, half will complete a program of pitch- perception testing and training that will be administered prior to the start of baseline testing (comparison of pitch matching data between groups with vs. without training will determine if the program improves within- session reliability of the pitch matching test). Finally, a third cohort of 100 of the previous study's participants will return to repeat testing ~3 years following their baseline testing to obtain long-term reliability data. In addition to data collection, efforts will be ongoing to complete development and validation of the tablet-based TES with the intent to ready this system for clinical application. A test protocol requiring 5-10 minutes is needed for the TES to have the potential to achieve more widespread use among VA audiologists. A rapid TES protocol will be developed, tested, and validated with a subset of participants to achieve this objective. Completing the work described in this application will accomplish many objectives, including making tinnitus psychoacoustic measures more useful and practical for clinical and research utilization.

我们之前的工作收集了耳鸣感知和耳鸣功能测量的规范数据 效果（反应）。未接受耳鸣针对性干预的慢性耳鸣参与者， 在0、1、3和6个月时完成耳鸣心理声学测量和耳鸣问卷。参加者 包括六个年龄范围（18-30；31-40；41-50；51-60；61-70；70+）。这些数据将有助于 一旦所有数据分析完成（最终参与者 测试于 2018 年 10 月 30 日进行）。拟议的研究将通过以下方式延伸和扩展这一努力：（1）建立 通过测试一组新参与者来建立规范标准数据库； (2) 长期评估 通过从参与者那里获得额外的纵向数据，耳鸣心理声学测量的可重复性 从之前的研究中回忆起； (3) 开发评估个人音调感知能力的方法 根据需要提供培训； (4)评价音调训练对耳鸣音调匹配能力的影响 更高的精度； (5) 持续开发基于平板电脑的耳鸣评估系统（TES） 通过改进界面和其他性能特征以及创建快速评估来实现临床实用性 程序可在 10 分钟内获得可靠的响度匹配和音高匹配。为了完成这些 为了实现目标，新参与者将被分为两个单独的群组，每组分别有 150 人和 100 人（新参与者总数 注册人数=250）。两组新参与者都将符合与 以前的研究。 150 名新参与者将在基线以及第 1、3 和 6 个月时接受重复测试，以达到最终效果。 重复之前研究期间所做的测试。 100 名新参与者组成的单独队列将 参加评估音高匹配培训计划。其中，一半将完成推介计划 将在基线测试开始之前进行感知测试和培训（比较 有训练组与无训练组之间的音调匹配数据将决定程序是否在以下范围内有所改进： 音高匹配测试的会话可靠性）。最后，第三组 100 名先前研究的参与者 将在基线测试后大约 3 年内返回重复测试，以获得长期可靠性数据。在 除了数据收集之外，还将继续努力完成基于平板电脑的开发和验证 TES 旨在使该系统为临床应用做好准备。需要 5-10 分钟的测试方案是 TES 需要有潜力在 VA 听力学家中得到更广泛的使用。快速 TES 协议将由一部分参与者开发、测试和验证，以实现这一目标。 完成本申请中描述的工作将实现许多目标，包括使耳鸣 心理声学测量对于临床和研究利用更加有用和实用。