Academic Leadership Award at the Indiana University School of Medicine

印第安纳大学医学院学术领导奖

• 批准号: 10077811
• 负责人: GARY E. LANDRETH
• 金额: $ 16.19万
• 依托单位: INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-01-01 至 2024-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10077811
• 关键词: Aging; Alzheimer' s Disease; Alzheimer' s disease model; Alzheimer' s disease related dementia; Animal Model; Award; Basic Science; Caliber; Clinical; Clinical Trials; Collaborations; Communities; Development; Doctor of Medicine; Educational Curriculum; Educational Status; Elements; Employee; Faculty; Foundations; Funding; Goals; Graduate Education; Home; Human Resources; Indiana; Individual; Infrastructure; Institutes; Institution; Instruction; Investments; Laboratories; Lead; Leadership; Medical; Modernization; Neurodegenerative Disorders; Neurosciences; Neurosciences Research; Postdoctoral Fellow; Presenile Alzheimer Dementia; Principal Investigator; Research; Research Activity; Research Institute; Research Personnel; Resources; Series; Talents; Training; Training Activity; Training Programs; Training Support; Translational Research; Universities; Work; academic program; aged; brain health; cell repository; cognitive function; design; doctoral student; experience; faculty research; graduate student; medical schools; post-doctoral training; programs; recruit; success; undergraduate research experience

Principal Investigator: Landreth, Gary E Project Summary/Abstract This academic leadership award application is directed at the development of coordinated and comprehensive educational programs in aging, Alzheimer’s disease and related dementias at the Indiana University School of Medicine (IUSM). A primary goal is to provide an organizational framework, anchored in the Medical Neurosciences Training Program, to functionally integrate the activities of existing and developing NIA supported resources at the IUSM. The NIA supports the Indiana Alzheimer’s Disease Research Center, the National Cell Repository for Alzheimer’s Disease, the Regenstrief Institute and the Center for Aging Research as well as the recently funded MODEL-AD center and LEADS clinical trial. Finally, Eli Lilly is headquartered in Indianapolis and has a substantial research effort focused on Alzheimer’s disease. These institutions comprise a unique and significant intellectual and infrastructural resource that will be leveraged in the current proposal. The IUSM and the NIA have recently committed substantial institutional resources to develop basic science research efforts on AD and neurodegenerative diseases. However, the success of the investigative effort will be contingent upon provision of a skilled workforce. The present application describes a plan to employ the Medical Neuroscience Training program as a vehicle to enhance and coordinate the research and training activities at the IUSM. The training program will simultaneously enhance and expand the institutional research capacity by providing a talented pool of young investigators to faculty within the individual research centers, and provide a high level training for these individuals. Importantly, the activities of the training program provide a mechanism to promote interactions and collaborations between the faculty and research staff at IUSM and Lilly who work on aging and neurodegenerative diseases. The applicant, Dr. Gary Landreth, was recruited to IUSM to lead the development and restructuring of the Medical Neurosciences Training Program. He brings to this effort 30 years of experience in Alzheimer’s disease research and graduate education. The Specific Aims of the application are:1) To restructure the Medical Neuroscience Training program through a) modernizing the graduate curriculum to provide foundational training in the Neurosciences, aging and neurodegenerative diseases, b) initiation of a postdoctoral training program to promote the professional advancement of this important component of the scientific workforce and c) provide undergraduate research experiences. 2) To employ the Medical Neuroscience Training Program as a vehicle to integrate the activities of the various IUSM centers focused on Aging and Neurodegenerative diseases. 3) To promote translational research interactions through the Medical Neuroscience Training Program with Eli Lilly.

主要研究者：Landreth，加里E 项目总结/摘要 这一学术领导奖的申请是针对协调和发展， 印第安纳州老年痴呆症和相关痴呆症的综合教育项目 大学医学院（IUSM）。主要目标是提供一个组织框架， 医学神经科学培训计划，在功能上整合现有和发展中的活动 NIA支持IUSM的资源。NIA支持印第安纳州阿尔茨海默病研究中心， 国家阿尔茨海默病细胞库、Regenstrief研究所和老龄化中心 研究以及最近资助的MODEL-AD中心和LEADS临床试验。最后，Eli Lilly 总部设在印第安纳波利斯，并有大量的研究工作集中在阿尔茨海默氏症。这些 机构是一种独特而重要的知识和基础设施资源， 目前的提案。 IUSM和NIA最近承诺提供大量机构资源， 在AD和神经退行性疾病方面的科学研究工作。然而，调查的成功 这项工作将取决于能否提供熟练的劳动力。本申请描述了一种计划， 采用医学神经科学培训计划作为工具，以加强和协调研究， IUSM的培训活动。培训计划将同时加强和扩大机构 通过提供一个年轻的研究人员人才库，以教师在个人研究的研究能力 中心，并为这些人提供高水平的培训。重要的是，培训活动 该计划提供了一种机制，以促进教师和研究之间的互动和合作 研究衰老和神经退行性疾病的IUSM和礼来公司的工作人员。 申请人加里·兰德雷斯（Gary Landreth）博士被招募到IUSM，领导该项目的开发和重组 医学神经科学培训计划。他带来了30年的阿尔茨海默氏症的经验 疾病研究和研究生教育。 申请的具体目的是：1）重组医学神经科学培训计划 通过a）使研究生课程现代化，以提供神经科学、老龄化、 B）启动博士后培训计划，以促进专业 促进科学劳动力的这一重要组成部分和c）提供本科研究 经验2)采用医学神经科学培训计划作为整合活动的工具 各种IUSM中心专注于衰老和神经退行性疾病。3)促进翻译 通过与礼来的医学神经科学培训计划进行研究互动。