Cellular and Molecular Imaging Core

细胞和分子成像核心，其中有其起源于1977年，促进了杰出的， 糖尿病研究中心附属机构在西雅图地区的创新研究， 在组织化学、显微成像和图像处理方面开创了新的方法和技术进步 分析.在下一个资助周期中，CMIC将继续促进这些研究人员的研究， （1）免疫组化和形态学定量评估 组织变化;（2）以具有成本效益的方式获得最先进的成像仪器;（3） 与糖尿病有关的专家技术和科学支持，包括研究方案的设计， 结果的解释;（4）获得比较病理学家，以协助实验和/或临床前 研究;和（5）实践和教学培训，以子公司，他们的学员和人员与常规和高度 专门的形态学、组织化学和成像技术。通过所有这些服务， 和分子成像核心非常重视确保高标准的严格性， 在核心中进行的研究的再现性。这包括但不限于严格的质量控制， 试剂，方案的专家审查，并确保适当和充分使用阳性和阴性 对照通过实现这些目标，细胞和分子成像核心将支持科学 调查附属研究者，他们将使用核心来进一步了解糖尿病、肥胖和 相关疾病。

The Cellular and Molecular Imaging Core, which had its origin in 1977, facilitates the outstanding and innovative research of Diabetes Research Center affiliates in the Seattle area by keeping pace with and pioneering new methodological and technical advances in histochemistry, microscopic imaging and image analysis. In the next funding cycle the CMIC will continue to promote the research of these investigators during the next funding cycle by providing: (1) Quantitative assessment of immunohistochemistry and morphological changes in tissues; (2) Access to state-of-the-art imaging instrumentation, in a cost-effective manner; (3) Expert diabetes-related technical and scientific support, including design of research protocols and interpretation of results; (4) Access to comparative pathologists, to assist with experimental and/or preclinical studies; and (5) Hands-on and didactic training to affiliates, their trainees and personnel with routine and highly specialized morphological, histochemical and imaging techniques. Through all of these services, the Cellular and Molecular Imaging Core places a great deal of emphasis on ensuring high standards of rigor and reproducibility for studies undertaken in the Core. This includes, but is not limited to, rigorous quality control for reagents, expert review of protocols and ensuring appropriate and adequate use of positive and negative controls. By achieving these goals, the Cellular and Molecular Imaging Core will support the scientific investigation of affiliate investigators who will use the core to further our understanding of diabetes, obesity and related disorders.