Surveillance of Diabetes in Young Adults between 18-45 Years of Age (DiCAYA) - Component B

18-45 岁年轻人糖尿病监测 (DiCAYA) - B 部分

• 批准号: 10084122
• 负责人: Tessa L Crume
• 金额: $ 24.95万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-30 至 2025-09-29
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10084122
• 关键词: Surveillance; Diabetes; Young; Adults; between

PROJECT SUMMARY People with diabetes are at high risk of developing a range of diverse microvascular, macrovascular and neuropathic complications that are associated with high morbidity and erode their quality of life. Diabetes is expected to take an increasingly large financial toll in in the United States (U.S.) the future, particularly among working age adults. Ongoing, timely and efficient surveillance of type 1 and type 2 diabetes diagnosed among young adults aged 18-45 years is essential to identify health disparities and inform health care systems and the public health community to identify and prioritize strategies to prevent diabetes and its complications. The Colorado DiCAYA surveillance team is ideally situated to address the critical challenge of utilizing existing electronic data sources to generate accurate, timely estimates of the incidence and prevalence of diabetes among the young adult population by type, age, sex, and race/ethnicity subgroups. In response to RFA-DP-20- 001- Component B, we propose to ascertain the annual prevalence and incidence of diabetes among adults aged 18-45 years of age in the state of Colorado starting with year 2020 from the following data sources: 1) electronic health records from the well-established SEARCH network of endocrinology clinics, community clinics and hospital networks in Colorado; 2) a state-wide, legislatively mandated All Payers Claims Database that contains over 33 commercial health plans and 100% of Medicaid claims; and 3) the University of Colorado Health System data warehouse (Health Data Compass). Our simple, yet innovative integrated surveillance approach will utilize a combination of algorithms, incremental record linkage and targeted chart review to identify young adults with diabetes, distinguish diabetes type and estimate date of diagnosis. Our specific aims are: Aim 1: SURVEILLANCE (Prevalence)- To ascertain cases of prevalent diabetes among young adults age 18-45 years, by age, race/ethnicity and diabetes type; Aim 2: SURVEILLANCE (Incidence)- To ascertain newly diagnosed diabetes cases in young adults age 18-45 years at diagnosis, by age, race and diabetes type; Aim 3: EVALUATE PUBLIC HEALTH SURVEILLANCE METHODS - To evaluate the strengths and challenges of our integrated surveillance approach to determine the burden and incidence of diabetes among young adults 18-45 years by ascertaining validity, completeness and representativeness of case ascertainment methods.

项目摘要 糖尿病患者处于发展一系列不同微血管、大血管和 与高发病率相关的神经性并发症并损害他们的生活质量。糖尿病是 预计将采取越来越大的财政损失在美国（美国）未来，尤其是 工作年龄的成年人。对确诊的1型和2型糖尿病进行持续、及时和有效的监测 在18-45岁的年轻人中， 和公共卫生界，以确定和优先战略，以预防糖尿病及其并发症。 科罗拉多迪卡亚监视小组的理想位置，以解决利用现有的关键挑战， 电子数据源，以准确、及时地估计糖尿病的发病率和患病率 按类型、年龄、性别和种族/族裔亚组分列的年轻成人人口中的性别比例。根据RFA-DP-20- 001-部分B，我们建议确定糖尿病的年患病率和发病率， 从2020年开始，科罗拉多州18-45岁的成年人，数据如下 资料来源：1）来自完善的内分泌诊所网络的电子健康记录， 社区诊所和医院网络在科罗拉多; 2）全州范围内，立法授权的所有付款人索赔 数据库包含超过33个商业健康计划和100%的医疗补助索赔;以及3） 科罗拉多卫生系统数据仓库（Health Data Compass）。我们简单而创新的集成式 监视方法将利用算法、增量记录链接和目标图表相结合 审查以确定患有糖尿病的年轻人，区分糖尿病类型并估计诊断日期。我们 具体目标是：目标1：监测（患病率）-确定 按年龄、人种/种族和糖尿病类型列出的18-45岁年轻人;目标2：监测 （发病率）-确定诊断时年龄为18-45岁的年轻人中新诊断的糖尿病病例， 年龄、种族和糖尿病类型;目标3：扩大公共卫生监测方法- 评估我们的综合监测方法的优势和挑战，以确定负担， 通过确定18-45岁年轻人糖尿病发病率的有效性、完整性和 案例确定方法的代表性。