Shared Resource Management

项目摘要-共享资源管理 ACC共享资源提供获得专门技术、服务、培训和专门知识的机会 这对加速ACC 324个成员的研究生产力至关重要。每个共享资源都与 ACC成员，学员和工作人员催化基础，转化，临床和人口科学癌症 研究，提供用户培训和支持校外资助和出版高 影响文件。在共享资源副总监塞莱斯特西蒙博士的指导下， 不断评估，以确保他们提供尖端技术和可访问的，具有成本效益的 为行政协调会成员的需要提供可靠的服务。我们提出以下三个目标：1） 支持高质量的共享资源，以满足ACC成员的科学需求，并促进 有效的研究活动; 2）确保ACC和机构共享资源的稳定性和可访问性 通过负责任的财政管理和过度使用政策; 3）确定科学的 确保当前和未来的共享资源满足成员的需求。ACC 行政部门与ACC领导层和西蒙博士密切合作，评估共享资源，监督 管理，并确保财政稳定，成本效益和增长机会。财政监督 共享资源通过一套应用程序（Path BioResource系统）集中完成 由佩雷尔曼医学院（PSOM）和ACC管理。战略规划定期 用户反馈和每个共享资源的内部咨询委员会保证了 质量.每个共享资源的ACC用户的百分比范围为32%-100%; 通过CCSG为支持每项共享资源提供的年度预算支持从7%到34%不等。为 在当前的资助期内，我们提出了九个完全共享资源- ACC生物储存库，生物统计学 生物信息学，比较病理学，流式细胞术和细胞分选，基因组分析，人类 免疫学，代谢组学，小动物成像，转基因和嵌合小鼠设施。基于 我们的战略规划过程和响应成员的科学需求，其中两个共享资源 (ACC生物储存库;代谢组学）都是新的，每一个都是从开发共享资源中产生的。 当前融资期。一个现有的共享资源的范围已经扩大（从生物统计学 生物统计学和生物信息学核心）。两个开发共享资源（小动物辐射 和电子表型分析）的建议，根据行政协调会成员的需要。ACC成员可以利用 PSOM有超过75个核心设施，其中24个经过PSOM生物医学研究中心的正式审查 设施委员会保证质量。通过ACC对共享资源的支持，成员可以访问 最先进的设备和仪器，技术专长，培训和教育，所有这些都旨在 支持创新的尖端癌症研究。

PROJECT SUMMARY – Shared Resource Management The ACC Shared Resources provide access to specialized technologies, services, training and expertise critical to accelerate research productivity for the 324 ACC members. Each Shared Resource engages with ACC members, trainees, and staff to catalyze basic, translational, clinical and population science cancer research, provide user training and support grant applications for extramural funding and publication of high impact papers. Under the direction of Dr. Celeste Simon, Associate Director for Shared Resources, they are continuously evaluated to ensure that they provide cutting edge technologies and accessible, cost-effective and reliable services that serve the needs of the ACC membership. We propose the following three aims: 1) Support high quality Shared Resources that serve the scientific needs of the ACC membership and catalyze impactful research activity; 2) Ensure stability of and access to ACC and institutional Shared Resources through responsible fiscal management and over-arching usage policies; and 3) Determine the scientific priorities of ACC members and ensure current and future Shared Resources meet membership needs. ACC Administration works closely with ACC Leadership and Dr. Simon in assessing Shared Resources, overseeing management, and ensuring fiscal stability, cost-effectiveness and opportunities for growth. Fiscal oversight of Shared Resources is accomplished through a suite of applications (Path BioResource system), centrally managed by the Perelman School of Medicine (PSOM) and ACC Administration. Strategic planning is regularly undertaken; user feedback and internal advisory boards for each Shared Resources guarantee cutting-edge quality. The percentage of ACC users for each Shared Resource ranges from 32%-100%; the percentage of annual budget support provided through CCSG to support each Shared Resource ranges from 7% to 34%. For the current funding period, we are proposing nine Full Shared Resources – ACC BioRepository, Biostatistics and Bioinformatics, Comparative Pathology, Flow Cytometry and Cell Sorting, Genomic Analysis, Human Immunology, Metabolomics, Small Animal Imaging, and Transgenic and Chimeric Mouse Facilities. Based on our strategic planning process and in response to members' scientific needs, two of these Shared Resources (ACC BioRepository; Metabolomics) are new, each emerging from Developing Shared Resources of the current funding period. One existing Shared Resource has been expanded in scope (from the Biostatistics Core to the Biostatistics and Bioinformatics Core). Two Developing Shared Resources (Small Animal Radiation and Electronic Phenotyping) are being proposed, based on ACC membership needs. ACC members can utilize over 75 Core Facilities at PSOM; 24 of these undergo formal review by the PSOM Biomedical Research Core Facilities Committee to assure quality. Through ACC support of Shared Resources, members have access to state-of the-art equipment and instrumentation, technical expertise, training and education, all designed to support innovative cutting-edge cancer research.