Pediatric Traumatic Hemorrhagic Shock Consensus Conference and Research Priorities

儿科创伤失血性休克共识会议和研究重点

• 批准号: 10132369
• 负责人: ROBERT T RUSSELL
• 金额: $ 2.86万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-04-01 至 2024-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10132369
• 关键词: Address; Adult; Algorithms; Anesthesia procedures; Award; Biological; Biology; Blood; Canada; Caring; Cessation of life; Child; Childhood; Childhood Injury; Clinical Trials; Clinical Trials Design; Collaborations; Colloids; Common Data Element; Communities; Consensus; Critical Care; Critical Illness; Data; Data Collection; Development; Dissemination and Implementation; Emergency Medicine; Epidemiology; Europe; Funding; Future; Generations; Goals; Hematology; Hemorrhage; Hemorrhagic Shock; Hemostatic Agents; Hemostatic function; Hospitals; Hypotension; Incidence; Interdisciplinary Study; International; Intravenous; Investigation; Israel; Knowledge; Laboratories; Lead; Literature; Mechanics; Medical; Medical Care Costs; Methods; Military Personnel; Mission; Monitor; Observational Study; Outcome; Paramedical Personnel; Patient Care; Pattern; Population; Practice Management; Pre-hospitalization care; Process; Publishing; Recommendation; Reporting; Research; Research Methodology; Research Personnel; Research Priority; Resuscitation; Shock; Societies; Standardization; Structure; Tourniquets; Tranexamic Acid; Transfusion; Trauma; Trauma Research; Traumatic Hemorrhage; Traumatic Shock; Traumatic injury; Travel; United States National Institutes of Health; Videoconferencing; base; blood pressure regulation; blood product; care providers; clinical care; clinical development; clinical practice; crystalloid; evidence base; implementation tool; improved; improved outcome; lectures; meetings; mortality; multidisciplinary; pediatric patients; pediatric trauma; preventable death; prospective; social media; statistics; support tools; symposium; tool; transfusion medicine; trauma care; trauma surgery; years of life lost

PROJECT SUMMARY We propose a multi-disciplinary conference led by a group of international experts focused on the current state of the art in pediatric traumatic hemorrhagic shock that will produce consensus statements on best practice based on the current literature. Consensus statements will also be generated to establish research priorities that include optimal methods of dissemination and implementation of high quality pediatric data to allow for the efficient change of clinical practice when appropriate. Consensus statements will be developed via a highly structured process to include the Delphi Method. A panel of 21 international experts (USA, Canada, Europe, Israel) that represent trauma surgery, transfusion medicine, hematology, anesthesia, critical care, and emergency medicine will form the consensus committee. Topics to be discussed include epidemiology and outcomes, biologic consequences of hemorrhagic shock, laboratory identification of hemorrhagic shock, transfusion strategies for both prehospital and in-hospital, consequences of crystalloid and colloid resuscitation, permissive hypotension, use of intravenous and mechanical hemostatic adjuncts, developing structured multicenter data collection tools to facilitate research, and methods for consensus generation. The conference will also lead to the generation of a multidisciplinary research network focused on the resuscitation of pediatric traumatic hemorrhagic shock. A similar network of investigators does not exist. The ability to bring together international leaders in pediatric trauma resuscitation and initiate a research network will accelerate the generation of many clinical trials in this field. To encourage trainees, and prehospital care providers (military medics and civilian paramedics) to participate in this conference reduced registration and travel awards will be available.

项目总结 我们提议召开一次由一组国际专家领导的多学科会议，重点关注当前的状况 儿科创伤性失血性休克的ART将产生关于最佳实践的共识声明 基于当前的文献。还将产生协商一致的声明，以确定研究优先事项 这包括传播和实施高质量儿科数据的最佳方法，以便 在适当的时候有效地改变临床实践。协商一致的声明将通过高度的 包含Delphi方法的结构化流程。由21名国际专家组成的专家组(美国、加拿大、欧洲、 以色列)，代表创伤外科、输血医学、血液学、麻醉、危重护理和 急诊医学将组成协商一致委员会。将讨论的主题包括流行病学和 结果，失血性休克的生物学后果，失血性休克的实验室鉴定， 院前和院内的输血策略：晶体和胶体的后果 复苏、允许性低血压、静脉和机械止血辅助设备的使用 结构化的多中心数据收集工具，以促进研究，以及达成共识的方法。这个 会议还将导致建立一个以复苏为重点的多学科研究网络 儿科创伤性失血性休克。类似的调查网络并不存在。带来的能力 联合儿科创伤复苏领域的国际领先者并启动研究网络将加快 在这一领域产生了许多临床试验。鼓励实习生和院前护理提供者 (军事医务人员和文职护理人员)参加这次会议减少了登记和旅行 奖项将可供选择。