Psychological and Socio-Environmental Determinants of Sleep and Neurocognitive Function (PEDS)

睡眠和神经认知功能 (PEDS) 的心理和社会环境决定因素

• 批准号: 10247848
• 负责人: Janeese Brownlow
• 金额: $ 20.6万
• 依托单位: DELAWARE STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-01 至 2022-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10247848
• 关键词: Affect; Chronic; Clinical; Delaware; Environment; Environmental Risk Factor; Goals; Interview; Investigation; Minority; Neurobiology; Neurocognitive; Neurosciences Research; Participant; Performance; Play; Psychological Factors; Psychological Models; Public Health; Quality of life; Questionnaires; Risk Factors; Risk Marker; Role; Sleep; Sleep disturbances; Social Environment; Stress; actigraphy; health disparity; improved; multimodality; neurobehavioral test; psychologic; social

Psychological and environmental stress, as well as disturbed sleep are important public health concerns and are independently known to significantly influence neurocognitive function. Compromised sleep is an essential risk factor and marker for chronic conditions that disproportionately affect urban minorities and further contribute to health disparities. There is a significant gap regarding sleep disparities, the potential role that the environment plays in such disparities, and how the relationship between sleep and neurocognitive performance may be moderated by psychological and social-environmental features. The goal of the proposed investigation is to establish a model where psychological and social-environmental features elicit sleep discontinuity that interferes with neurocognitive function. To accomplish this goal, we will employ multimodal approaches (e.g. clinical interviews, actigraphy, neurobehavioral tests, questionnaires). Psychological factors will be assessed by clinical interview and the role of social-environmental features by utilizing a battery of questionnaires to assess for stressful environmental factors. We will then have participants complete one week of actigraphy to assess for objective sleep continuity and habitual sleep. Finally, we will examine neurocognitive performance by utilizing a comprehensive neurocognitive battery. Study findings will identify specific psychological and environmental risk factors of neurocognitive performance related to habitual sleep. Further, these findings will be instrumental in moving the field toward a more useful integration of environmental, clinical, and neurobiological understanding that may improve quality of life and reduce the societal burden of sleep disparities.

心理和环境压力以及睡眠障碍是重要的公共卫生问题， 都能显著影响神经认知功能睡眠不足是一种 对城市少数群体影响尤为严重的慢性病的基本风险因素和标志， 进一步加剧了健康差距。关于睡眠差异存在着显著的差距， 环境在这种差异中起作用，以及睡眠和神经认知之间的关系 表现可能受到心理和社会环境特征的调节。建议的目标 研究的目的是建立一个心理和社会环境特征引起睡眠的模型 干扰神经认知功能的中断。为了实现这一目标，我们将 多模式方法（例如，临床访谈、体动记录、神经行为测试、问卷）。 心理因素将通过临床访谈进行评估，社会环境特征的作用将通过 利用一系列问卷来评估压力环境因素。我们将有 参与者完成一周的活动记录以评估客观睡眠连续性和习惯性睡眠。 最后，我们将利用一个全面的神经认知电池检查神经认知性能。 研究结果将确定神经认知障碍的特定心理和环境风险因素。 与习惯性睡眠有关。此外，这些发现将有助于将该领域推向 环境、临床和神经生物学理解的更有用的整合， 提高生活质量，减少睡眠不均衡的社会负担。