Continuation of the Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) Data Coordinating Center
下尿路功能障碍症状延续研究网络 (LURN) 数据协调中心
基本信息
- 批准号:10246242
- 负责人:
- 金额:$ 12.02万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2013
- 资助国家:美国
- 起止时间:2013-07-25 至 2024-08-31
- 项目状态:已结题
- 来源:
- 关键词:Ancillary StudyBar CodesBiologicalBiological AssayBiological MarkersBladderCase Report FormCharacteristicsChargeClinicalClinical ManagementClinical ResearchClinical TreatmentClinical TrialsCollaborationsCommunicationCommunitiesComplexConsensusDataData AnalysesData CollectionData Coordinating CenterDevelopmentDiagnosisDiagnosticDiseaseFunctional disorderFundingFutureGoalsHuman ResourcesInfrastructureInstitutional Review BoardsInternistKnowledgeLeadLeadershipLogisticsLower urinary tractManuscriptsMeasurementMeasuresModelingMonitorMotorNational Institute of Diabetes and Digestive and Kidney DiseasesOrganOutcomeParticipantPatient CarePatient MonitoringPatient Self-ReportPatient-Focused OutcomesPatientsPerformancePhasePhenotypePhysiologicalPilot ProjectsPlasmaPoliciesPopulationProcessPublicationsReportingResearchResearch DesignResearch PersonnelSamplingScientistSecureSelf AssessmentSensorySeveritiesSiteSubgroupSurveysSymptomsSystemTestingTimeTreatment outcomeUrethraUrinary Tract FindingUrinary tractUrodynamicsUrologistWomanWorkWritingbasecare outcomesclinical phenotypeclinical research sitecohortdata managementdesigndissemination researchexpectationexperienceimprovedinsightinstrumentlower urinary tract symptomsmeetingsmennovelpatient subsetsprotein biomarkersprotocol developmentquality assurancerecruitresearch studyresponsesymposiumsymptom treatmenttertiary caretooltreatment responsetreatment trialurinaryweb site
项目摘要
Project Summary
In the Continuation of the Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN II), the
investigators will advance the subtyping of study participants with Lower Urinary Tract Symptoms (LUTS) with
the expectation that clinically useful patient subtypes will be identified. Research efforts will include continued
analysis of data and biospecimens from LURN I and development of additional, new and novel collaborative
studies to further improve our understanding of lower urinary tract dysfunction, both designed to generate
findings that may inform future clinical studies (e.g., clinical treatment trials) and ultimately improve clinical
management and patient outcomes.
Studies will also refine and evaluate the longitudinal performance of clusters identified in LURN I for patient
subtyping, including response to treatment. We will incorporate insights from the LURN I organ-based
diagnostics pilot study and biomarker pilot studies. We will evaluate the LURN Comprehensive Assessment of
Self-reported Urinary Symptoms (CASUS) instrument in populations with lesser severity of LUTS than seen in
the tertiary care setting in LURN I.
Consistent with the description in the RFA for this second funding cycle of LURN, the primary goal of this
proposal is to better define clinical phenotypes of patients with LUTS, to better describe the impact and
diversity of symptoms, and to develop new patient-centric tools for improved measurement of clinical
symptoms, all with the goals of informing future clinical studies and improving patient care and outcomes. It is
anticipated that the network will consist of up to six clinical sites and a single data coordinating center (DCC).
The DCC for the LURN study is charged with providing coordination, communications and logistical support,
clinical study design, centralized data management, biosample management, quality assurance, and analytical
support to the research sites and the NIDDK Project Scientist for all LURN studies. The proposing team is
submitting this response to RFA-DK-18-511 to continue as the DCC for the network.
项目总结
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Robert M Merion其他文献
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{{ truncateString('Robert M Merion', 18)}}的其他基金
Expansion of Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN)
下尿路功能障碍症状研究网络 (LURN) 的扩展
- 批准号:
8585774 - 财政年份:2013
- 资助金额:
$ 12.02万 - 项目类别:
Expansion of Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN)
下尿路功能障碍症状研究网络 (LURN) 的扩展
- 批准号:
9067345 - 财政年份:2013
- 资助金额:
$ 12.02万 - 项目类别:
Expansion of Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN)
下尿路功能障碍症状研究网络 (LURN) 的扩展
- 批准号:
9296129 - 财政年份:2013
- 资助金额:
$ 12.02万 - 项目类别:
Continuation of the Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) Data Coordinating Center
下尿路功能障碍症状延续研究网络 (LURN) 数据协调中心
- 批准号:
10488066 - 财政年份:2013
- 资助金额:
$ 12.02万 - 项目类别:
Continuation of the Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) Data Coordinating Center
下尿路功能障碍症状延续研究网络 (LURN) 数据协调中心
- 批准号:
10251160 - 财政年份:2013
- 资助金额:
$ 12.02万 - 项目类别:
Expansion of Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN)
下尿路功能障碍症状研究网络 (LURN) 的扩展
- 批准号:
9547580 - 财政年份:2013
- 资助金额:
$ 12.02万 - 项目类别:
Expansion of Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN)
下尿路功能障碍症状研究网络 (LURN) 的扩展
- 批准号:
8877506 - 财政年份:2013
- 资助金额:
$ 12.02万 - 项目类别:
Expansion of Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN)
下尿路功能障碍症状研究网络 (LURN) 的扩展
- 批准号:
8705513 - 财政年份:2013
- 资助金额:
$ 12.02万 - 项目类别:
Expansion of Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN)
下尿路功能障碍症状研究网络 (LURN) 的扩展
- 批准号:
9336639 - 财政年份:2013
- 资助金额:
$ 12.02万 - 项目类别:
Novel Control Group to Expand the Scope of the RELIVE Living Kidney Donor Study
新型对照组扩大了 RELIVE 活体肾脏捐赠者研究的范围
- 批准号:
8427235 - 财政年份:2012
- 资助金额:
$ 12.02万 - 项目类别: