Efficacy of the WeCareAdvisor: An Online Tool to Help Caregivers Manage Behavioral and Psychological Symptoms in Persons with Dementia
WeCareAdvisor 的功效:帮助护理人员管理痴呆症患者行为和心理症状的在线工具
基本信息
- 批准号:10247666
- 负责人:
- 金额:$ 75.46万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2019
- 资助国家:美国
- 起止时间:2019-08-01 至 2024-04-30
- 项目状态:已结题
- 来源:
- 关键词:AddressAggressive behaviorAgitationAlgorithmsAlzheimer&aposs DiseaseAlzheimer&aposs disease related dementiaAntipsychotic AgentsBehaviorBehavior monitoringBehavioralBehavioral SymptomsCaregiversCaringCaucasiansCommunicationComplexControl GroupsCustomDementiaDevelopmentDiseaseDisease ProgressionDistressEducationElectronic MailEnvironmentEtiologyEvaluationFDA approvedFamilyFamily CaregiverFamily memberFrequenciesFundingGoalsGrantHealth PersonnelKnowledgeLearningLeftMediator of activation proteinMotivationNursing HomesOnline SystemsOutcomePainPersonsPharmaceutical PreparationsRaceRandomizedReadinessReportingResearchReview LiteratureRiskSamplingSelf EfficacySeriesSeveritiesSocietiesSpousesSymptomsTelephoneTestingUnited States National Academy of SciencesWaiting Listsbasecare systemscostdementia caredesignefficacy testingefficacy trialfamily burdenfamily caregivingfamily supporthealth care service utilizationhigh riskimprovedmortalitynovelpreventprimary endpointpsychological symptomracial diversityrandomized trialresponseside effectskillssymposiumtooltreatment grouptreatment planningusabilityweb-based tool
项目摘要
Behavioral and psychological symptoms (agitation, aggression, among many others; aka BPSD) are hallmarks
of Alzheimer's disease and related dementias (ADRD). BPSD dominate disease presentation, occur across
etiologies and disease trajectories, and have significant negative consequences for persons with dementia,
family members, and society at-large. Although there are no FDA approved medications to treat BPSD,
psychotropic medications (including anti-psychotics) are commonly used with limited efficacy and high risk.
Nonpharmacologic strategies are considered first-line treatments and have proven efficacy, but families have
little knowledge of and access to strategies and are left on their own to manage BPSD. In response, we
developed an easy-to-use, web-based platform, WeCareAdvisor, through a previously funded NINR grant (R01
NR014200) for use by family caregivers. The tool provides caregivers with knowledge about dementia, daily
tips, and a systematic approach for describing, investigating, creating and evaluating strategies using an
approach we developed (DICE) that systematically guides selection of strategies to match symptom
presentation. Our pilot randomized study (N=57; NIA-Stage 1) compared an initial treatment group to a 1-
month waitlist control with caregivers receiving weekly telephone calls and emails encouraging tool use. This
pilot demonstrated proof-of-concept with 100% of caregivers using the tool. After 1 month of use, both the
initial treatment and the waitlist control groups showed significant within group benefits in caregiver (distress,
confidence) and BPSD (frequency and severity) outcomes. Additionally, there was significant improvement in
caregiver distress in the initial treatment group as compared to the waitlist group. Unclear, is whether prompts
were necessary for tool use and/or to derive benefit. In response to PAR-18-027, we propose to test the
efficacy of WeCareAdvisor (NIA - Stage II) and tool utilization in 326 diverse caregivers using a two-group,
randomized design; caregivers will be assigned to immediate treatment or 3-month waitlist control groups. Our
specific aims are to test: 1) Short-term efficacy (1-month) of WeCareAdvisor on caregiver distress, confidence
managing BPSD, or BPSD frequency and severity; 2) Longer-term efficacy (3-months) of WeCareAdvisor on
caregiver distress, confidence managing BPSD, or BPSD frequency and severity. We will also examine
whether the waitlist control group demonstrates similar benefits after using the tool over a 3-month exposure;
and 3) Tool utilization and outcomes using different reminders (telephone + email or email only). We will also
evaluate whether tool utilization is sustained without prompts in months 3-6 for the initial treatment group.
Exploratory aims will examine frequency of use of tool components, impact on psychotropic medication use,
function, and other outcomes; and mediator (theoretically-derived variables), and moderator (race, relationship)
effects. This proposal is novel in assessing efficacy and utilization of a tool that has great potential to impact
dementia care by providing caregivers with on-demand access to BPSD management strategies.
行为和心理症状(躁动、攻击性等,又名BPSD)是其特征
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Laura N. Gitlin其他文献
A Biobehavioral Home-Based Intervention and the Well-being of Patients With Dementia and Their Caregivers
生物行为家庭干预和痴呆症患者及其护理人员的福祉
- DOI:
- 发表时间:
2017 - 期刊:
- 影响因子:0
- 作者:
Laura N. Gitlin;Marie P. Dennis;N. Hodgson;Walter W. Hauck - 通讯作者:
Walter W. Hauck
“The Filter is Kind of Broken”: Family Caregivers' Attributions About Behavioral and Psychological Symptoms of Dementia
- DOI:
10.1016/j.jagp.2017.12.004 - 发表时间:
2018-05-01 - 期刊:
- 影响因子:
- 作者:
Courtney A. Polenick;Laura M. Struble;Barbara Stanislawski;Molly Turnwald;Brianna Broderick;Laura N. Gitlin;Helen C. Kales - 通讯作者:
Helen C. Kales
In Search of Psychological Benefits
寻求心理益处
- DOI:
- 发表时间:
1992 - 期刊:
- 影响因子:0
- 作者:
Laura N. Gitlin;M. P. Lawton;Lisa A. Windsor;M. Kleban;Laura P. Sands;J. Posner - 通讯作者:
J. Posner
Family dementia caregivers with suicidal ideation improve with mentalizing imagery therapy: Results from a pilot study
有自杀意念的家庭痴呆症护理人员通过心理意象疗法得到改善:一项试点研究的结果
- DOI:
- 发表时间:
2024 - 期刊:
- 影响因子:0
- 作者:
Saira Madarasmi;Paulina Gutierrez‐Ramirez;Nader Barsoum;Sreya Banerjee;Liliana Ramirez Gomez;Maria Melero‐Dominguez;Laura N. Gitlin;Aderonke Pederson;Richard T. Liu;Felipe A Jain - 通讯作者:
Felipe A Jain
Understanding the implementation process of the Adult Day Services Plus program
- DOI:
10.1186/s12877-025-05757-4 - 发表时间:
2025-02-13 - 期刊:
- 影响因子:3.800
- 作者:
Quinton D. Cotton;Dionne Bailey;Elle Albers;Steph Ingvalson;Emily Bloomquist;Katie Marx;Keith Anderson;Holly Dabelko-Schoeny;Lauren Parker;Laura N. Gitlin;Joseph E. Gaugler - 通讯作者:
Joseph E. Gaugler
Laura N. Gitlin的其他文献
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{{ truncateString('Laura N. Gitlin', 18)}}的其他基金
Efficacy of the WeCareAdvisor: An Online Tool to Help Caregivers Manage Behavioral and Psychological Symptoms in Persons with Dementia
WeCareAdvisor 的功效:帮助护理人员管理痴呆症患者行为和心理症状的在线工具
- 批准号:
10665635 - 财政年份:2019
- 资助金额:
$ 75.46万 - 项目类别:
Efficacy of the WeCareAdvisor: An Online Tool to Help Caregivers Manage Behavioral and Psychological Symptoms in Persons with Dementia
WeCareAdvisor 的功效:帮助护理人员管理痴呆症患者行为和心理症状的在线工具
- 批准号:
10447723 - 财政年份:2019
- 资助金额:
$ 75.46万 - 项目类别:
Efficacy of the WeCareAdvisor: An Online Tool to Help Caregivers Manage Behavioral and Psychological Symptoms in Persons with Dementia
WeCareAdvisor 的功效:帮助护理人员管理痴呆症患者行为和心理症状的在线工具
- 批准号:
9979719 - 财政年份:2019
- 资助金额:
$ 75.46万 - 项目类别:
The Johns Hopkins Alzheimer's Disease Resource Center for Minority Aging Research - Research Ed Component
约翰·霍普金斯大学阿尔茨海默氏病资源中心少数民族老龄化研究 - 研究版组件
- 批准号:
10451582 - 财政年份:2018
- 资助金额:
$ 75.46万 - 项目类别:
A Training and Fidelity Model to Move and Scale Evidence-based Dementia Care and Caregiver Support Programs into Practice: The Case for COPE in PACE service settings
将循证痴呆症护理和护理人员支持计划付诸实践的培训和保真模型:PACE 服务环境中的 COPE 案例
- 批准号:
10186679 - 财政年份:2018
- 资助金额:
$ 75.46万 - 项目类别:
A Training and Fidelity Model to Move and Scale Evidence-based Dementia Care and Caregiver Support Programs into Practice: The Case for COPE in PACE service settings
将循证痴呆症护理和护理人员支持计划付诸实践的培训和保真模型:PACE 服务环境中的 COPE 案例
- 批准号:
10468726 - 财政年份:2018
- 资助金额:
$ 75.46万 - 项目类别:
A Training and Fidelity Model to Move and Scale Evidence-based Dementia Care and Caregiver Support Programs into Practice: The Case for COPE in PACE service settings
将循证痴呆症护理和护理人员支持计划付诸实践的培训和保真模型:PACE 服务环境中的 COPE 案例
- 批准号:
9789806 - 财政年份:2018
- 资助金额:
$ 75.46万 - 项目类别:
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