Core B: Pathology Core

核心 B：病理学核心

• 批准号: 10249092
• 负责人: Giorgio Inghirami
• 金额: $ 21.12万
• 依托单位: WEILL MEDICAL COLL OF CORNELL UNIV
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-18 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10249092
• 关键词: Academic Medical Centers; Adherence; Archives; Biological; Biopsy; CD19 gene; Cell Cycle; Cell Separation; Cell Survival; Cells; Clinical; Clinical Data; Clinical Trials; Collaborations; Complement; Cytogenetic Analysis; Data; Databases; Diagnosis; Diagnostic; Ensure; Flow Cytometry; Government; Hematologist; Image Analysis; Immunohistochemistry; In Vitro; Individual; Institution; Institutional Review Boards; Internet; Intervention; Left; Liquid substance; Lymphoma cell; Malignant Neoplasms; Mantle Cell Lymphoma; Medicine; Methods; Molecular Target; Morphology; Mus; Ohio; Pathology; Patients; Pharmacotherapy; Process; Prognosis; Protocols documentation; Quality Control; Research Personnel; Sampling; Scientist; Secure; Services; Solid; Specimen; Speed; Stains; Surgeon; System; Technical Expertise; Testing; Time; Tissue Banks; Tissue Microarray; Tissue Procurements; Tissues; Update; Videoconferencing; base; clinical diagnostics; design; digital imaging; good laboratory practice; individual patient; magnetic beads; mouse model; multidisciplinary; novel therapeutics; patient population; preservation; programs; radiologist; repository; research and development; success; tissue resource; translational study

SUMMARY The primary purposes of the pathology core will be: procure patient specimens, characterize and assess the specimens as required by projects and for clinical trials, provide data to the projects and other cores, bank tissue, and distribute tissue to the projects. Our current and past efforts have shown that the centralization of specimens, analysis, and data provided by the core facilitates collaboration between other cores and projects. For example, whereas individual projects might be able to provide some of these services for themselves, centralization provides a degree of consistency and reliability that enables the confident exchange of parallel information, derived from methods with a level of quality control that could not be achieved outside of a dedicated core. Also, because we have already derived methods tailored to the needs of similar projects, we are uniquely suited to devise or revise systems as needed to provide services. Because mantle cell lymphoma (MCL) is an uncommon cancer, the combination of the Ohio State University Medical Center (OSUMC) and Weill Cornell Medicine (WCM) tissue resources are critical to the success of this PPG. We have designed these services to optimize the use of our two centers, while keeping overlap to a minimum. The unique expertise of WCM and that of OSUMC complement each other, resulting in a breadth of services that would not be possible on any single campus. !

总结 病理学核心的主要目的是：获取患者标本，表征和评估 根据项目和临床试验的需要，为项目和其他核心提供数据，库 组织，并分发组织的项目。我们目前和过去的努力表明， 核心小组提供的样本、分析和数据促进了其他核心小组和项目之间的合作。 例如，尽管单个项目可能能够为自己提供其中的一些服务， 集中化提供了一定程度的一致性和可靠性， 信息来源于质量控制水平的方法，这些方法无法在 专用核心此外，由于我们已经根据类似项目的需要导出了方法， 是唯一适合设计或修改系统所需的提供服务。因为套细胞淋巴瘤 (MCL)是一种罕见的癌症，俄亥俄州州立大学医学中心（OSUMC）和 Weill Cornell Medicine（WCM）组织资源对于PPG的成功至关重要。我们设计了 这些服务，以优化我们的两个中心的使用，同时保持重叠到最低限度。独特的 WCM的专业知识和OSUMC的专业知识相互补充，从而提供广泛的服务， 这在任何一个校园都是不可能的。 !