The Arizona Department of Health Services Food Safety and Food Defense Project

亚利桑那州卫生服务部食品安全和食品防护项目

• 批准号: 10256690
• 负责人: Ward B. Jacox
• 金额: $ 69.25万
• 依托单位: ARIZONA STATE DEPARTMENT OF HLTH SRVCS
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-01 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10256690
• 关键词: Arizona; Department; Health; Services; Food

Arizona Department of Health Services LFFM Grant Application Projects 1-7 Summary The Arizona Department of Health Services Laboratory (ASPHL) has capacity in Chemical, Microbiological, and Radiological testing to analyze food products for like contamination at both preparedness and regulatory levels. ASPHL is a FERN Laboratory under ISO 17025 accreditation for the analysis of food defense analytes and seeks to maintain that capability in both chemical and microbiological disciplines as well as expanding into radiochemical analysis for the duration of the 5-year project timeline. (CHEM / MICRO / RAD Tract 1). The ASPHL is the primary servicing laboratory for the testing of manufactured human food for the State of Arizona and seeks to introduce chemical food safety testing for metals and allergens on samples collected by state and county partners under the Manufactured Food Regulatory Program Standards (MFRPS) guidelines. (CHEM Tract 2). The ASPHL is partnered with Translational Genomics Research Laboratory (TGEN) for the yearly sequencing of 400 isolates of Salmonella, E. coli, Campylobacter and Listeria monocytogenes and will continue as a founding member of the FDA’s GenomeTrakr. Subrecipient TGEN has identified greater than 1000 isolates of target organisms to consider for whole genome sequencing on human food. (MICRO Tract 4). Method development is a strength of the ASPHL and the Chemistry Laboratory proposes to continue this activity with the development and validation of compliance level Allergen Testing using the MagPix System with XPonent 4.2 software with the end product being a written analytical method to submit to the FDA NPO for review. (CHEM Tract 4). The ASPHL FERN Chemistry is strong on metals analysis using ICP-MS and LC-ICP-MS and proposes to engage in a multi-laboratory validation of the Elemental Analysis manual method EAM 4.12: Analysis of Bottled Water by ICP-MS. The method will be validated two different ICP- MS platforms: an Agilent 7700 ICP-MS coupled to an Agilent 1200 uHPLC system and an Agilent 8900 ICP-triple quadruple-MS coupled with an Agilent 1260 infinity II. (CHEM SP D3).

亚利桑那州卫生服务部LFFM资助申请项目1-7摘要 亚利桑那州卫生服务部实验室（ASPHL）有能力在化学， 微生物和放射性测试，以分析食品中的类似污染， 准备和监管水平。ASPHL是ISO 17025下的FERN实验室 食品防御分析物的分析认证，并寻求保持这种能力， 化学和微生物学科以及扩展到放射化学分析 5年项目时间轴的持续时间。(CHEM/ MICRO / RAD Tract 1）。 ASPHL是主要的服务实验室，用于检测人类食品的制造， 亚利桑那州，并寻求引入化学食品安全测试的金属和 过敏原的样本收集的州和县合作伙伴根据制成品 监管计划标准（MFRPS）指南。(CHEM道2）。 ASPHL与翻译基因组学研究实验室（TGEN）合作， 每年对400株沙门氏菌、E.大肠杆菌、弯曲杆菌和李斯特菌 他将继续作为FDA GenomeTrakr的创始成员。 亚载体TGEN已确定了超过1000种可考虑的目标微生物分离株 人类食物的全基因组测序（MICRO Tract 4）. 方法开发是ASPHL的强项，化学实验室建议 通过开发和验证符合性水平的过敏原检测继续开展这项活动 使用带有XPonent 4.2软件的MagPix系统，最终产品为书面 分析方法提交给FDA NPO进行审查。(CHEM道4）。 ASPHL FERN化学在使用ICP-MS和LC-ICP-MS进行金属分析方面很强， 建议对元素分析手动方法进行多实验室验证 EAM 4.12：通过ICP-MS分析瓶装水。该方法将通过两种不同的ICP- MS平台：与Agilent 1200 uHPLC系统偶联的Agilent 7700 ICP-MS，和 与Agilent 1260 infinity II耦合的Agilent 8900 ICP-三重四重-MS。(CHEM SP D3）。