SCH: INT: A Virtual Surgery Simulator to Accelerate Medical Training in Cardiovascular Disease

SCH：INT：加速心血管疾病医疗培训的虚拟手术模拟器

• 批准号: 10259714
• 负责人: Alison L Marsden
• 金额: $ 25.8万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-30 至 2023-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10259714
• 关键词: 3-Dimensional; Anatomic Models; Anatomy; Back; Biomechanics; Blood flow; Cardiac; Cardiology; Cardiovascular Diseases; Cardiovascular system; Case Study; Clinical; Clinical Research; Collaborations; Computational Science; Computer Graphics; Custom; Education; Educational Assessment; Educational Curriculum; Engineering; Ensure; Feedback; Geometry; Goals; Hand; High Performance Computing; Immersion; Intuition; Knowledge acquisition; Learning; Liquid substance; Manuals; Measures; Medical; Medical Students; Medicine; Methodology; Methods; Modeling; Monitor; Operating Rooms; Operative Surgical Procedures; Pathology; Patient-Focused Outcomes; Patients; Physicians; Physics; Physiological; Physiology; Pilot Projects; Postoperative Period; Quick Test for Liver Function; Research; Running; Science; Students; Surgeon; Techniques; Technology; Time; Training; Translating; Universities; Visualization; Work; base; cluster computing; cohort; design; educational atmosphere; experience; experimental study; follow-up; hands-on learning; individual patient; innovation; insight; instructor; medical schools; models and simulation; multidisciplinary; novel; open source; pedagogy; repository; simulation; success; tool; virtual environment; virtual reality; virtual reality environment; virtual reality simulation; virtual surgery

We propose to devise and deploy an integrated virtual surgery simulator to transform training and surgical planning in cardiovascular medicine. By advancing science in graphics, visualization and real-time simulations, and interfacing with virtual reality (VR) technology, we will offer clinical trainees unprecedented depth of insight into cardiac physiology and pathology, accelerating knowledge acquisition and intuition-building that takes years with standard approaches. Equipped with immersive patient-specific visualizations, physicians will 'preview' the effects of surgical techniques on blood flow and physiology, quickly testing many "what-if" scenarios over a large design space. While surgeons currently teach trainees time-honored techniques in a steep and high-stakes learning curve, novel and intuitive VR environments will enable rapid, lower-stakes exploration. Despite advances in cardiovascular patient-specific modeling and simulation, current virtual surgery capabilities are limited to cumbersome by-hand model manipulations and blood flow simulations run on high-performance computing clusters for days at a time. These complexities preclude hands-on use by clinicians and often limit models to a small cohort of anatomic designs. There is, therefore, a pressing need for scientific and technological advances to enable seamless manipulation of anatomic geometry and simulations that can provide real-time feedback. To drive this technology, we aim to overcome critical methodological barriers through the following aims: 1) Develop computer-graphics tools for efficient model manipulation, 2) Integrate reduced-order modeling with visualization to create a real-time interactive experience, and 3) Develop and deploy an interactive VR educational environment for medical students and clinical trainees, complete with case studies and interactive experiences. To quantify impact, we will design and carry out educational assessments measuring the ability of our technology to accelerate learning among medical trainees. To ensure success, we have assembled an expert interdisciplinary team spanning cardiovascular biomechanics, computer graphics, technology in education, and clinical cardiology. Ultimately, the proposed tools will also drive clinical innovation. Since many cardiovascular surgical approaches have changed little in decades, a longer-term goal is to launch clinical studies demonstrating impact on patient outcomes, allowing surgical planning and customization for individual patients.

我们建议设计和部署一个集成的虚拟手术模拟器，以改变培训和手术 心血管医学的规划。通过推进图形、可视化和实时科学 模拟，并与虚拟现实（VR）技术接口，我们将提供临床实习生 对心脏生理学和病理学前所未有的深入洞察，加速知识获取 和直觉的建立，这需要多年的标准方法。配备沉浸式患者专用 通过可视化，医生将“预览”手术技术对血流和生理的影响， 在大的设计空间上快速测试许多“假设”场景。虽然外科医生目前教 学员在陡峭和高风险的学习曲线中使用历史悠久的技术，新颖直观的VR 环境将使快速，低风险的勘探成为可能。尽管心血管疾病的进展 患者特定的建模和模拟，目前的虚拟手术能力仅限于繁琐的 手动模型操作和血流模拟在高性能计算集群上运行， 一次几天这些复杂性妨碍了临床医生的实际操作，并且通常将模型限制在较小的范围内。 解剖设计队列。因此，迫切需要科学和技术的进步 以实现对解剖几何结构和模拟的无缝操纵， 反馈为了推动这项技术的发展，我们的目标是通过 以下目标：1）开发有效的模型操作的计算机图形工具，2）集成 具有可视化的降阶建模，以创建实时交互式体验，以及3）开发和 为医学生和临床实习生部署交互式VR教育环境，完成 案例研究和互动体验。为了量化影响，我们将设计和实施 教育评估衡量我们的技术加速医疗人员学习的能力， 实习生为了确保成功，我们组建了一支跨学科的专家团队， 心血管生物力学、计算机图形学、教育技术和临床心脏病学。 最终，所提出的工具也将推动临床创新。由于许多心血管外科手术 虽然几十年来治疗方法几乎没有改变，但长期目标是开展临床研究，证明 对患者结局的影响，允许为个体患者制定手术计划和定制。