The efferent synapse in enteroendocrine cells

抽象的。 我们母公司研究计划的长期目标是记录胃肠道(GI) TRAIL通过周围神经将管腔信号传递到大脑，以及这些神经是如何 调节胃肠感觉功能。这份美日BRPC行政补充文件的目标是 Diego Bohórquez博士(家长资助P.I.)是杜克大学(北卡罗来纳州达勒姆)的神经科学家 美国)拜访迈克尔·赫夫曼博士，他是灵长类研究所的灵长类行为学家 京都大学(名古屋，日本)。这次访问的目的是获得先进的研究技能 并开始进行合作研究，以揭示自我用药的神经基础。在……里面 具体而言，并与R21AT010818 NIH-NCCIH家长资助的目标相关 关于“肠内分泌细胞中的突触”，这次访问将有两个具体目标： 1.学习野外研究灵长类动物自我用药的科学方法 在灵长类研究所。 2.确定潜在的药用植物和化合物，以便在杜克大学进行测试。 一旦表征，这些化合物可用于缓解行为障碍 通过瞄准肠道感官功能。 通过学习如何在野外识别和研究自我用药行为，我们将能够 把这项工作转移到我们的实验室。此外，通过鉴定具有药用价值的植物， 这些化合物可以用来调节肠道感觉功能，以努力治疗行为 通过调节肠道感觉功能而引起的疾病。

Abstract. The long-term goal of our parent research program is to document how the gastrointestinal (GI) tract transduces luminal signals to the brain via peripheral nerves and how these nerves modulate GI sensory function. The goal of this US-Japan BRPC administrative supplement is for Dr. Diego Bohórquez (parent grant P.I) who is a neuroscientist at Duke University (Durham, NC, USA) to visit Dr. Michael Huffman who is a primate behaviorist at the Primate Research Institute of Kyoto University (Nagoya, Japan). The goal of the visit is to acquire advanced research skills and start to conduct collaborative research to uncover the neural basis of self-medication. In particular, and related to the goals of the R21AT010818 NIH-NCCIH parent grant “The efferent synapse in enteroendocrine cells”, the visit will have two specific aims: 1. To learn the scientific methodology used to study self-medication in primates in the field at the Primate Research Institute. 2. To identify potential medicinal plants and compounds to test back at Duke University. Once characterized these compounds could be used to alleviated behavioral disorders by targeting gut sensory function. By learning how self-medicating behaviors are identified and studied in the wild, we will be able to translate that work to our laboratory. Moreover, by identifying plants with medicinal values, these compounds could be used to modulate gut sensory function in an effort to treat behavioral disorders by modulating gut sensory function.