Animal Models Module

项目摘要-动物模型 动物模型模块提供了对理解 疾病背后的机制和开发新的治疗方法。动物模型模块 提供最先进的设备，使威尔默学院能够表演小动物 手术，建立动物模型，监测疾病进展和测试潜力 治疗。添加了模块的新功能，以支持生成 转基因斑马鱼的眼部疾病模型。该模块的设备 包括两个带有蔡司天花板悬挂式显微镜的手术室以及两个ERG 机器，两台哈佛微型注射器，一台Bioptogen SDOCT机器，一台OptoMotry 光动力学装置和Micron III成像系统。动物手术室是 被威尔默学院广泛使用，并已帮助产生了超过65 过去五年的出版物。动物模型模块由Gerard博士运行 Lutty和Malia Edwards，他们提供有关使用所有设备的培训。爱德华兹博士 定期监督手术室和设备是否处于良好的工作状态 根据需要组织服务。这些设施确保威尔默学院继续 处于眼科研究的前沿。

PROJECT SUMMARY – ANIMAL MODELS The animal model module provides facilities that are crucial to both understanding the mechanisms behind disease and developing new treatments. The animal model module provides state of the art equipment enabling the Wilmer Faculty to perform small animal surgery, generate animal models, monitor disease progression and test potential treatments. A new capability of the module has been added to support the generation of genetically engineered Zebrafish models of ocular disease. The module's equipment includes two operating suites with Zeiss ceiling hung microscopes as well as two ERG machines, two Harvard micro-injectors, a Bioptogen SDOCT machine, an OptoMotry optokinetics unit, and a Micron III imaging system. The animal operating rooms are used extensively by Wilmer Faculty and have been helped to generate over 65 publications in the past five years. The animal model module is run by Drs. Gerard Lutty and Malia Edwards who provide training on the use of all equipment. Dr. Edwards routinely monitors the operating rooms and equipment are in good working order and organizes servicing as needed. These facilities ensure that Wilmer Faculty continue to be on the cutting edge of eye research.