Using Remote Sensing Technology to Assess Parent-Infant Interactions as a Mechanism Linking COVID-related Stress and Infant Neurobehavioral Functioning

使用遥感技术评估亲子互动，作为将新冠病毒相关压力与婴儿神经行为功能联系起来的机制

• 批准号: 10239919
• 负责人: Nancy L McElwain
• 金额: $ 23.48万
• 依托单位: UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-30 至 2021-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10239919
• 关键词: Address; Affect; Age; Age-Months; Arkansas; Attenuated; Behavior; Brain; COVID-19; COVID-19 pandemic; Caring; Cessation of life; Child; Child Care; Child Development; Church; Collection; Communities; Community Services; Coping Skills; Data; Development; Distress; Emotional; Enrollment; Environment; Equilibrium; Family; Foundations; Geography; Health; Health Sciences; Home; Home Economics; Home environment; Human; Illinois; Income; Infant; Intervention; Job loss; Laboratories; Lead; Life; Light; Link; Machine Learning; Medical center; Mental Health; Mind; Mothers; Motion; New York; North Carolina; Oregon; Outcome; Parents; Participant; Patient Recruitments; Pattern; Pediatric Hospitals; Phase; Physiological; Physiology; Play; Process; Psychophysiology; Regulation; Reporting; Research; Research Institute; Research Personnel; Resources; Risk; Risk Factors; Role; SARS-CoV-2 infection; Safety; Sampling; Signal Transduction; Site; Social support; Speech; Stress; Surveys; Testing; Time; Transact; United States National Institutes of Health; Universities; Visit; caregiving; coping; coronavirus disease; depressive symptoms; economic impact; experience; falls; infancy; infection rate; interest; machine learning method; maternal stress; motor behavior; multimodal data; multimodality; neurobehavioral; new technology; novel; pandemic disease; patient home care; phase 1 study; physical conditioning; protective factors; remote sensing; resilience; sensor technology; social culture; stressor; substance use; virtual; virtual visit; vocalization

The young child’s ability to regulate stress sets the foundation for a host of developmental outcomes, and the parent-infant relationship is the primary context in which stress regulation capacities first develop. Prior research underscores how parents’ own stress may lead to disturbances in parent-infant co-regulation of stress. Given the immense disruptions to family life resulting from the COVID-19 pandemic, it is critical to understand the degree to which COVID-related stress may impact the parent-infant relationship and ultimately infants’ neurobehavioral outcomes. We posit here that (a) maternal stress due to the pandemic will be associated with disturbances in the mother-infant relationship, particularly with respect to mother-infant co- regulation of infant distress and (b) mothers’ experiences of COVID-related stress will have an indirect effect on infant neurobehavioral outcomes, in part, due to disturbances to the mother-infant relationship. We also aim to investigate risk factors (e.g., maternal depressive symptoms, substance use; infant negative emotionality) that might exacerbate such linkages, as well as protective factors (e.g., maternal social support, coping) that may attenuate them. We will partner with six sites from the NIH HEALthy Brain and Child Development Study- Phase 1 (New York University, Oregon Health Sciences University, Cedars-Sinai Medical Center, University of North Carolina at Chapel Hill, Cincinnati Children’s Hospital, Arkansas Children’s Research Institute) that will permit addressing the proposed aims among a geographically diverse sample of 240 families with infants between 6 and 18 months of age. To assess key constructs relevant to mother-infant relationship disturbance, we will use a novel multimodal sensing platform that captures infant vocalizations, stress physiology, and motor behavior, and we will employ machine learn approaches to these multimodal data to yield automated assessments of mother-infant co-regulation of infant distress. By combining assessments of (a) mothers’ COVID-related experiences, as well as maternal, family, and infant functioning, collected by the six HBCD sites via maternal reports and virtual visits and (b) mother-infant co-regulation of stress in home environments using remote multimodal sensing technology, the current study will provide unique opportunities for a nuanced and rich understanding of the effects of the COVID-19 pandemic on infants born during this unprecedented time.

幼儿调节压力的能力为一系列发展结果奠定了基础， 父母-婴儿关系是压力调节能力首先发展的主要环境。之前 研究强调了父母自身的压力如何可能导致父母-婴儿共同调节的紊乱， 应力鉴于COVID-19大流行对家庭生活造成的巨大破坏， 了解COVID相关压力可能影响亲子关系的程度，并最终 婴儿的神经行为结果。我们在此重申，（a）由于这一流行病造成的产妇压力将是 与母婴关系障碍有关，特别是在母婴共同 婴儿痛苦的调节和（B）母亲的COVID相关压力经历将产生间接影响 对婴儿神经行为结果的影响，部分原因是母婴关系的干扰。我们还旨在 调查风险因素（例如，母亲抑郁症状，物质使用;婴儿消极情绪） 可能加剧这种联系的因素，以及保护性因素（例如，母亲的社会支持，应对）， 可能会削弱它们。我们将与来自NIH健康大脑和儿童发育研究的六个研究中心合作， 第1阶段（纽约大学、俄勒冈州健康科学大学、雪松-西奈医学中心、 北卡罗来纳州查佩尔山、辛辛那提儿童医院、阿肯色州儿童研究所）， 允许在地理位置不同的240个有婴儿的家庭样本中实现拟议的目标 年龄在6到18个月之间。评估与母婴关系障碍相关的关键结构， 我们将使用一种新颖的多模态传感平台，它可以捕捉婴儿的发声、压力生理学， 运动行为，我们将采用机器学习方法来处理这些多模态数据， 评估母婴共同调节婴儿痛苦。通过综合评估（a）母亲的 六个六溴环十二烷研究中心收集的与新冠病毒相关的经历以及孕产妇、家庭和婴儿功能 和（B）在家庭环境中的压力的母婴共同调节， 遥感多模态传感技术，目前的研究将提供一个微妙的独特的机会， 丰富了解COVID-19大流行对在这一前所未有的时期出生的婴儿的影响。