Using Remote Sensing Technology to Assess Parent-Infant Interactions as a Mechanism Linking COVID-related Stress and Infant Neurobehavioral Functioning

使用遥感技术评估亲子互动，作为将新冠病毒相关压力与婴儿神经行为功能联系起来的机制

• 批准号: 10239919
• 负责人: Nancy L McElwain
• 金额: $ 23.48万
• 依托单位: UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-30 至 2021-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10239919
• 关键词: Address; Affect; Age; Age-Months; Arkansas; Attenuated; Behavior; Brain; COVID-19; COVID-19 pandemic; Caring; Cessation of life; Child; Child Care; Child Development; Church; Collection; Communities; Community Services; Coping Skills; Data; Development; Distress; Emotional; Enrollment; Environment; Equilibrium; Family; Foundations; Geography; Health; Health Sciences; Home; Home Economics; Home environment; Human; Illinois; Income; Infant; Intervention; Job loss; Laboratories; Lead; Life; Light; Link; Machine Learning; Medical center; Mental Health; Mind; Mothers; Motion; New York; North Carolina; Oregon; Outcome; Parents; Participant; Patient Recruitments; Pattern; Pediatric Hospitals; Phase; Physiological; Physiology; Play; Process; Psychophysiology; Regulation; Reporting; Research; Research Institute; Research Personnel; Resources; Risk; Risk Factors; Role; SARS-CoV-2 infection; Safety; Sampling; Signal Transduction; Site; Social support; Speech; Stress; Surveys; Testing; Time; Transact; United States National Institutes of Health; Universities; Visit; caregiving; coping; coronavirus disease; depressive symptoms; economic impact; experience; falls; infancy; infection rate; interest; machine learning method; maternal stress; motor behavior; multimodal data; multimodality; neurobehavioral; new technology; novel; pandemic disease; patient home care; phase 1 study; physical conditioning; protective factors; remote sensing; resilience; sensor technology; social culture; stressor; substance use; virtual; virtual visit; vocalization

The young child’s ability to regulate stress sets the foundation for a host of developmental outcomes, and the parent-infant relationship is the primary context in which stress regulation capacities first develop. Prior research underscores how parents’ own stress may lead to disturbances in parent-infant co-regulation of stress. Given the immense disruptions to family life resulting from the COVID-19 pandemic, it is critical to understand the degree to which COVID-related stress may impact the parent-infant relationship and ultimately infants’ neurobehavioral outcomes. We posit here that (a) maternal stress due to the pandemic will be associated with disturbances in the mother-infant relationship, particularly with respect to mother-infant co- regulation of infant distress and (b) mothers’ experiences of COVID-related stress will have an indirect effect on infant neurobehavioral outcomes, in part, due to disturbances to the mother-infant relationship. We also aim to investigate risk factors (e.g., maternal depressive symptoms, substance use; infant negative emotionality) that might exacerbate such linkages, as well as protective factors (e.g., maternal social support, coping) that may attenuate them. We will partner with six sites from the NIH HEALthy Brain and Child Development Study- Phase 1 (New York University, Oregon Health Sciences University, Cedars-Sinai Medical Center, University of North Carolina at Chapel Hill, Cincinnati Children’s Hospital, Arkansas Children’s Research Institute) that will permit addressing the proposed aims among a geographically diverse sample of 240 families with infants between 6 and 18 months of age. To assess key constructs relevant to mother-infant relationship disturbance, we will use a novel multimodal sensing platform that captures infant vocalizations, stress physiology, and motor behavior, and we will employ machine learn approaches to these multimodal data to yield automated assessments of mother-infant co-regulation of infant distress. By combining assessments of (a) mothers’ COVID-related experiences, as well as maternal, family, and infant functioning, collected by the six HBCD sites via maternal reports and virtual visits and (b) mother-infant co-regulation of stress in home environments using remote multimodal sensing technology, the current study will provide unique opportunities for a nuanced and rich understanding of the effects of the COVID-19 pandemic on infants born during this unprecedented time.

幼儿调节压力的能力为许多发展成果奠定了基础， 父母的关系是应力调节能力首先发展的主要背景。事先的 研究强调了父母自己的压力如何导致父母共同调节的灾难 压力。鉴于COVID-19大流行造成的家庭生活造成了极大的破坏，至关重要 了解与共同相关的压力可能影响父母的关系的程度，并最终 婴儿的神经行为结局。我们肯定的是，（a）大流行引起的物质压力将是 与母亲关系中的干扰有关，特别是在母亲共同的共同 调节婴儿痛苦和（b）母亲的共同压力经历将具有间接影响 关于婴儿神经行为结果，部分原因是对母亲关系的干扰。我们也瞄准 调查危险因素（例如，母体抑郁症状，使用物质；婴儿负面情绪） 这可能会加剧这种联系，以及保护因素（例如，社会支持，应对） 可能会衰减它们。我们将与NIH健康大脑和儿童发展研究的六个站点合作 - 第1阶段（纽约大学，俄勒冈州健康科学大学，锡达尔大学医学中心，大学 北卡罗来纳州的北卡罗来纳州教堂山，辛辛那提儿童医院，阿肯色州儿童研究所） 允许在240个有婴儿的家庭的地理样本中解决拟议的目标 在6到18个月之间。评估与母亲关系障碍相关的关键结构， 我们将使用一个新型的多模式传感平台，以捕获婴儿的发声，压力生理和 运动行为，我们将采用机器学习这些多模式数据的方法来产生自动化 对婴儿痛苦共同调节的评估。通过结合（a）母亲的评估 由六个HBCD站点收集 通过材料报告和虚拟访问以及（b）使用家庭环境中压力的母亲共同调节 远程多模式传感技术，当前的研究将为细微差别和 对199日大流行对在这个前所未有的时代中出生的婴儿的影响的丰富理解。