Methodology core
方法论核心
基本信息
- 批准号:10251978
- 负责人:
- 金额:$ 36.42万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2017
- 资助国家:美国
- 起止时间:2017-09-20 至 2022-09-15
- 项目状态:已结题
- 来源:
- 关键词:AccountingAddressAdherenceBehavior TherapyBehavioralBiochemicalBioinformaticsCaringClinicalClinical ResearchClinical TrialsCommunitiesComplexConduct Clinical TrialsConsultationsCounselingDataData AnalysesData CollectionData Management ResourcesData SetDiseaseEnsureEnvironmental Risk FactorEquilibriumEthicsExperimental DesignsFacultyFeasibility StudiesFocus GroupsGenetic RiskGoalsGrantHealthHealth Insurance Portability and Accountability ActHealth PromotionInformation TechnologyInterdisciplinary StudyInterventionLanguageLevel of EvidenceLinkLongevityMethodologyMethodsMissionMonitorMusculoskeletalMusculoskeletal DiseasesObservational StudyOnline SystemsOutcomePatient PreferencesPatientsPerceptionPersonal SatisfactionPersonsPhenotypePhysical activityProbabilityPrognosisQuality of lifeRandomizedRandomized Controlled TrialsRegulationReportingResearchResearch DesignResearch PersonnelResourcesRheumatismRheumatologyRisk AssessmentSafetySelf ManagementStatistical Data InterpretationSumToxic effectTranslationsTreatment EfficacyWeightWorkadvanced analyticsbasebehavioral economicsclinical careclinical practicecomparative effectiveness studycostcost effectivenessdata managementdesigndisorder riskeffectiveness studyepidemiology studyethnic minority populationexperiencefollow-uphealth disparityhigh riskimaging biomarkerimprovedimproved outcomeinnovationinstrumentlongitudinal analysismembermethod developmentnovelnovel strategiespatient engagementpatient orientedpreferenceracial minorityrecruittheoriestherapy designtrial designwearable device
项目摘要
ABSTRACT
The foci of expertise in the VERITY Methodology Core align with the overall objectives of the CCCR
(“VERITY”). First, VERITY is the hub of rheumatic and MSK disease clinical research in our growing, vibrant
Research Community, and the Core has the breadth of expertise to enhance the rigor of the broad range of
studies undertaken in our Research Community. Second, one of the key VERITY objectives is to design
interventions whose efficacy should be evaluated in studies providing the highest level of evidence, including
RCTs when feasible and observational studies when randomization cannot occur. The Methodology Core will
contribute to this mission by optimizing trial design to expedite the translation of efficacious new treatments into
clinical practice. Similarly, the Core’s work on prioritization of RCTs is needed to focus resources on trials that
have the greatest opportunity to advance clinical care. Finally, the Core advances VERITY’s focus on patient-
centeredness. We have the ability to harness advancements in information technology and health-promoting
wearable devices to design and implement studies that improve patients’ engagement, self-management,
adherence, physical activity, and well-being. Care can be personalized and outcomes improved through novel
interventions that draw from genetic and environmental risk assessment and counseling, disease risk
calculators, behavioral economics, health coaching, and efforts to reduce health disparities. The key Specific
Aims of the Methodology Core are: Aim 1: To ensure the highest possible methodological rigor in the design
and implementation of studies aimed at improving outcomes in persons with rheumatic and musculoskeletal
conditions. Aim 2: To develop and advance methods to optimize design and conduct of clinical trials. Aim 3:
To incorporate intervention approaches based on behavioral theory and behavioral economic principles and to
infuse cultural perspectives and perceptions of racial and ethnic minorities into interventions.
The Methodology Core links innovative ideas from the Research Community with rigorous study designs,
innovative trials, methods development, data management and analysis, compliance with data safety and
Health Insurance Portability and Accountability Act (HIPAA) regulations, and clear reporting of findings.
摘要
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Elena Losina其他文献
Elena Losina的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Elena Losina', 18)}}的其他基金
HIV and musculoskeletal frailty: implications for care, policy and research
艾滋病毒和肌肉骨骼脆弱:对护理、政策和研究的影响
- 批准号:
10686114 - 财政年份:2022
- 资助金额:
$ 36.42万 - 项目类别:
HIV and musculoskeletal frailty: implications for care, policy and research
艾滋病毒和肌肉骨骼脆弱:对护理、政策和研究的影响
- 批准号:
10552738 - 财政年份:2022
- 资助金额:
$ 36.42万 - 项目类别:
Optimizing the value of pain management in knee OA patients with comorbidities
优化疼痛管理对患有合并症的膝骨关节炎患者的价值
- 批准号:
10197756 - 财政年份:2018
- 资助金额:
$ 36.42万 - 项目类别:
Optimizing the value of pain management in knee OA patients with comorbidities
优化疼痛管理对患有合并症的膝骨关节炎患者的价值
- 批准号:
9975101 - 财政年份:2018
- 资助金额:
$ 36.42万 - 项目类别:
Optimizing the value of pain management in knee OA patients with comorbidities
优化疼痛管理对患有合并症的膝骨关节炎患者的价值
- 批准号:
10468625 - 财政年份:2018
- 资助金额:
$ 36.42万 - 项目类别:
相似海外基金
Pharmacy-led Transitions of Care Intervention to Address System-Level Barriers and Improve Medication Adherence in Socioeconomically Disadvantaged Populations
药房主导的护理干预转型,以解决系统层面的障碍并提高社会经济弱势群体的药物依从性
- 批准号:
10594350 - 财政年份:2023
- 资助金额:
$ 36.42万 - 项目类别:
Evaluating Centralizing Interventions to Address Low Adherence to Lung Cancer Screening Follow-up in Decentralized Settings
评估集中干预措施,以解决分散环境中肺癌筛查随访依从性低的问题
- 批准号:
10738120 - 财政年份:2023
- 资助金额:
$ 36.42万 - 项目类别:
Suubi-Mhealth: A mobile health intervention to address depression and improve ART adherence among Youth living with HIV (YLHIV) in Uganda
Suubi-Mhealth:一种移动健康干预措施,旨在解决乌干达艾滋病毒感染者 (YLHIV) 青少年的抑郁症问题并提高抗逆转录病毒疗法的依从性
- 批准号:
10526768 - 财政年份:2022
- 资助金额:
$ 36.42万 - 项目类别:
Suubi-Mhealth: A mobile health intervention to address depression and improve ART adherence among Youth living with HIV (YLHIV) in Uganda
Suubi-Mhealth:一种移动健康干预措施,旨在解决乌干达艾滋病毒感染者 (YLHIV) 青少年的抑郁症问题并提高抗逆转录病毒疗法的依从性
- 批准号:
10701072 - 财政年份:2022
- 资助金额:
$ 36.42万 - 项目类别:
A behavioral intervention for Black men who have sex with men and live with HIV to address intersectional stigma and improve antiretroviral therapy adherence
针对男男性行为且感染艾滋病毒的黑人男性进行行为干预,以解决交叉耻辱并提高抗逆转录病毒治疗的依从性
- 批准号:
10679092 - 财政年份:2021
- 资助金额:
$ 36.42万 - 项目类别:
A behavioral intervention for Black men who have sex with men and live with HIV to address intersectional stigma and improve antiretroviral therapy adherence
针对男男性行为且感染艾滋病毒的黑人男性进行行为干预,以解决交叉耻辱并提高抗逆转录病毒治疗的依从性
- 批准号:
10432133 - 财政年份:2021
- 资助金额:
$ 36.42万 - 项目类别:
A behavioral intervention for Black men who have sex with men and live with HIV to address intersectional stigma and improve antiretroviral therapy adherence
针对男男性行为且感染艾滋病毒的黑人男性进行行为干预,以解决交叉耻辱并提高抗逆转录病毒治疗的依从性
- 批准号:
10327065 - 财政年份:2021
- 资助金额:
$ 36.42万 - 项目类别:
Leveraging Technology to Address Access and Adherence to Conventional Hospital-Based Pulmonary Rehabilitation in Veterans with COPD
利用技术解决慢性阻塞性肺病退伍军人接受和坚持传统医院肺康复的问题
- 批准号:
10377366 - 财政年份:2019
- 资助金额:
$ 36.42万 - 项目类别:
Leveraging Technology to Address Access and Adherence to Conventional Hospital-Based Pulmonary Rehabilitation in Veterans with COPD
利用技术解决慢性阻塞性肺病退伍军人接受和坚持传统医院肺康复的问题
- 批准号:
10574496 - 财政年份:2019
- 资助金额:
$ 36.42万 - 项目类别:
Targeted interventions to address the multi-level effects of gender-based violence on PrEP uptake and adherence among adolescent girls and young women in Kenya
有针对性的干预措施,以解决性别暴力对肯尼亚少女和年轻妇女接受和坚持 PrEP 的多层面影响
- 批准号:
9403567 - 财政年份:2017
- 资助金额:
$ 36.42万 - 项目类别: