A Clinical Center to Study Immunological and Hormonal Biomarkers for the Diagnosis, Prediction and Treatment of Chronic Pancreatitis and its associated development to Diabetes and Pancreas Cancer

研究用于诊断、预测和治疗慢性胰腺炎及其与糖尿病和胰腺癌相关发展的免疫和激素生物标志物的临床中心

• 批准号: 10252512
• 负责人: Aida Habtezion
• 金额: $ 9.04万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-05 至 2021-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10252512
• 关键词: Administrative Supplement; Biological Markers; Childhood; Clinical Research; Collection; Development; Diabetes Mellitus; Diagnosis; Diagnostic tests; Enrollment; Evaluation; Funding; Hormonal; Immunologics; International; Lead; Longitudinal cohort study; Malignant neoplasm of pancreas; Pancreatitis; Patient Recruitments; Patients; Protocols documentation; Research; Secondary to; Specimen; Testing; chronic pancreatitis; clinical center; cost; epidemiology study; insight; novel diagnostics; prospective; recruit; translational study

Project Summary/Abstract This application is for an administrative supplement to support our participation in the Consortium for the Study of Chronic Pancreatitis, Diabetes and Pancreas Cancer (CPDPC). It will specifically enable the Stanford Clinical Center to continue its productive recruitment of patients into 3 key clinical studies of the consortium – 1) Prospective Evaluation of Chronic Pancreatitis for Epidemiologic and Translational Studies (PROCEED), 2) Pediatric Longitudinal Cohort Study of Chronic Pancreatitis [The International Study Group of Pediatric Pancreatitis: In Search for a Cure (INSPPIRE2), and 3) Evaluation of a mixed meal test for Diagnosis and characterization of Pancreaticogenic Diabetes secondary to pancreatic cancer and chronic pancreatitis (DETECT). These funds will support patient related costs in enrollment and fulfilling protocol-defined tasks including the collection and processing of biospecimens for each protocol.

项目总结/摘要 此申请是一个行政补充，以支持我们参与联盟， 慢性胰腺炎、糖尿病和胰腺癌的研究（CPDPC）。它将特别使 斯坦福大学临床中心继续其富有成效的招募患者参加3项关键临床研究 1）慢性胰腺炎的流行病学和 转化研究（PROCEED），2）慢性胰腺炎的儿科纵向队列研究 [The国际儿科胰腺炎研究小组：寻找治疗方法（INSPPIRE 2），和3） 混合餐试验对胰源性糖尿病诊断和定性的评价 继发于胰腺癌和慢性胰腺炎（DETECT）。这些资金将用于支持患者 入组和完成方案规定任务（包括收集和处理）的相关费用 每个方案的生物标本数量。