Clinical Research Pilot Project Program

临床研究试点项目计划

• 批准号: 10260446
• 负责人: NICOLA LONGO
• 金额: $ 8.79万
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-16 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10260446
• 关键词: Biological Assay; Biological Markers; Biopterin; Clinical; Clinical Research; Clinical Trials; Cognitive; Data; Defect; Development; Diagnosis; Disease; Emotional; Evaluation; Funding; Grant; Hyperphenylalaninaemias; Laboratories; Lead; Longitudinal Studies; Morbidity - disease rate; Natural History; Outcome; Performance; Pilot Projects; Prevention; Protocols documentation; Rare Diseases; Registries; Testing; Therapeutic Intervention; data mining; innovation; instrument; novel; novel marker; programs; skills

6. PROJECT SUMMARY – PILOT CORE The Pilot Core will provide funding to studies of innovative ideas or hypotheses that, if successful, will lead to improvements in the understanding, prevention, diagnosis, or treatment of hyperphenylalaninemia, biopterin defects, and related disorders. The core will fund the development of novel laboratory assays or instruments, assessment of novel biomarkers, execution of pilot clinical trials, or performance of pilot data mining studies on data accumulated from the longitudinal natural history study.

6.项目概要-试点核心 试点核心将为创新想法或假设的研究提供资金，如果成功，将导致 提高对高苯丙氨酸血症、生物蝶呤的理解、预防、诊断或治疗 缺陷和相关疾病。该核心将资助开发新的实验室分析或仪器， 评估新的生物标志物，进行初步临床试验，或进行初步数据挖掘研究， 从纵向自然史研究中积累的数据。