Pediatric Biopsychology Core

儿科生物心理学核心

• 批准号: 10090148
• 负责人: Jennifer Christine Wolff
• 金额: $ 31.71万
• 依托单位: EMMA PENDLETON BRADLEY HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-04-06 至 2026-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10090148
• 关键词: Achievement; Address; Adolescent; Area; Behavioral; Biological Markers; Blood specimen; Catalogs; Centers of Research Excellence; Child; Child Care; Childhood; Circadian Rhythms; Clinical Research; Collection; Computerized Medical Record; Computers; Concept Formation; Consultations; Data; Data Analyses; Data Collection; Databases; Development; Educational workshop; Emergency medical service; Emerging Technologies; Ensure; Ethics; Eye; Family; Genetic Variation; Goals; Guidelines; Harvest; Health Insurance Portability and Accountability Act; Hormones; Hospitals; Immunologic Markers; Infrastructure; Knowledge; Laboratories; Libraries; Licensing; Link; Logistics; Measurement; Measures; Medical Records; Mental Health; Mental disorders; Mentors; Methods; Monitor; National Institute of Mental Health; Participant; Patient Self-Report; Pediatric Research; Practice Guidelines; Practice based research; Procedures; Process; Protocols documentation; Publications; Reporting; Reproducibility; Research; Research Domain Criteria; Research Infrastructure; Research Personnel; Research Project Grants; Research Training; Resources; Rhode Island; Sampling; Science; Secure; Services; Shipping; Sleep; Symptoms; System; Techniques; Technology; Training; Trust; United States National Institutes of Health; Update; Vendor; Work; advanced system; base; biobank; central database; clinical care; cognitive testing; data harmonization; data management; data repository; data resource; data streams; design; eligible participant; epigenetic variation; evidence base; experience; health assessment; informant; innovation; microbiome; mobile application; multidisciplinary; multimodality; open data; programs; psychobiology; psychologic; repository; research study; saliva sample; secondary analysis; service providers; sleep health; stool sample; web app

Project Summary/Abstract This COBRE aims to build a program for supporting excellence and innovation in research addressing sleep, circadian rhythms (CR), and mental health. Resources that bridge sleep and CR science and pediatric mental health research are limited, and opportunities for research training in these areas lack a coordinated system to link these important and interconnected constructs. The overall objective of the Pediatric Biopsychological Core (PBC) is to address this gap by connecting promising researchers to experienced mentors and creating a supportive infrastructure for enhancing research that includes evidence-based assessment of mental health, sleep, and the collection of biospecimens. To support this overarching goal, the PBC aims to 1) develop a culture of excellence by coordinating the administration of evidence-based assessment measures and practices; 2) provide resources for data collection, management, and analysis and the use of technology- based resources in the study of biopsychological factors in the context of sleep and circadian rhythms; and 3) provide resources for collection, storage, and processing of biospecimens. The PBC will offer Project Leaders individualized guidance for assessments of pediatric biopsychological. The Core will also enhance diversity in research by offering culturally sensitive measures and resources to promote inclusion. The PBC will also support Project Leaders in using rigorous data management procedures in accordance with current best practice and open science guidelines. The Core will also maintain a secure, HIPAA-compliant database to store multimodal and intensive data streams that will include shared assessment batteries as a resource for current and future research. The long-term goals of the Core are to 1) develop a sustainable resource for pediatric psychological assessment and biospecimens to enhance and promote high-quality research at Bradley Hospital; 2) provide resources for the management and analysis of these data; and 3) consistent with NIH priorities, develop a combined, centralized database with an eye towards data harmonization. Achievement of these aims will result in enhanced research infrastructure by providing a measurement resource that can help researchers integrate the demands of clinical care with the common domains articulated in the NIMH Research Domain Criteria (RDoC) framework. Having a center of excellence focused on measurement will greatly facilitate the research of COBRE-affiliated projects as well as research across the hospital and other Rhode Island facilities by helping to harmonize the assessment of common domains across clinical care and research projects. This COBRE will ensure that Bradley Hospital continues to be a state-wide and national leader in both research and care of children and adolescents with sleep and mental health concerns.

项目摘要/摘要 这个Cobre旨在建立一个项目，支持针对睡眠的研究中的卓越和创新， 昼夜节律(CR)和心理健康。连接睡眠、认知无线电科学和儿科精神医学的资源 卫生研究有限，这些领域的研究培训机会缺乏一个协调的系统来 将这些重要的、相互关联的结构联系起来。儿科生物心理学的总体目标 CORE(PBC)旨在通过将有前途的研究人员与经验丰富的导师联系起来并创建一个 加强研究的支持性基础设施，包括基于证据的精神健康评估， 睡眠，以及生物标本的收集。为了支持这一总体目标，中国人民银行的目标是：1)制定一项 通过协调循证评估措施的管理和 2)为数据收集、管理和分析以及技术的使用提供资源-- 在睡眠和昼夜节律背景下研究生物心理学因素方面的基础资源；以及3) 为收集、储存和加工生物标本提供资源。中国人民银行将为项目负责人提供 儿科生物心理学评估的个体化指导。核心还将增强 通过提供对文化敏感的措施和资源来促进包容性的研究。中国人民银行还将 支持项目负责人按照当前最佳水平使用严格的数据管理程序 实践和开放的科学指南。核心还将维护一个安全的、符合HIPAA的数据库，以 存储将包括共享评估电池作为资源的多模式密集型数据流 当前和未来的研究。核心的长期目标是1)开发可持续的资源，用于 儿科心理评估和生物显微镜，以加强和促进高质量的研究 布拉德利医院；2)为这些数据的管理和分析提供资源；3)与 国家卫生研究院的优先事项，开发一个着眼于数据统一的综合、集中的数据库。 这些目标的实现将通过提供一种衡量标准来加强研究基础设施 可以帮助研究人员将临床护理需求与公共领域相结合的资源 在NIMH研究领域标准(RDoC)框架中阐明。拥有专注于卓越中心的 关于测量的研究将极大地促进Cobre附属项目的研究以及跨 医院和罗德岛州的其他设施，帮助协调对所有公共领域的评估 临床护理和研究项目。这个科布雷将确保布拉德利医院继续成为全州范围内的 在睡眠和心理健康儿童和青少年的研究和护理方面处于全国领先地位 担忧。