NCI Research Specialist (Clinician Scientist) Award

NCI 研究专家（临床科学家）奖

• 批准号: 10569403
• 负责人: Karyn A Goodman
• 金额: $ 9.11万
• 依托单位: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-03-17 至 2028-02-29
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10569403
• 关键词: Address; Adjuvant; American College of Radiology Imaging Network; Award; Cancer and Leukemia Group B; Catchment Area; Clinical Cancer Center; Clinical Oncology; Clinical Research; Clinical Trials; Clinical Trials Cooperative Group; Clinical Trials Network; Colorado; Development; Eastern Cooperative Oncology Group; Equity; Faculty; Fostering; Funding; Funding Mechanisms; Goals; Growth; Health system; Hospitals; Institution; Investigational Therapies; Malignant Neoplasms; Malignant neoplasm of esophagus; Malignant neoplasm of pancreas; Minority Recruitment; NCI-Designated Cancer Center; National Clinical Trials Network; New York City; Oncology; Patients; Play; Positioning Attribute; Positron-Emission Tomography; Principal Investigator; Radiation Oncology; Radiation Therapy Oncology Group; Research; Resectable; Role; Scientist; Services; Specialist; The University of Colorado Cancer Center; Work; cancer care; cancer clinical trial; chemoradiation; drug development; fighting; gastrointestinal; improved; investigator-initiated trial; patient population; phase II trial; phase III trial; programs

ABSTRACT Dr. Karyn Goodman plays a critical role in Tisch Cancer Institute’s (TCI) cancer clinical trial program and in supporting NCI-funded clinical trials. She has demonstrated a long-term commitment to this work through her previous role as Associate Director (AD) of Clinical Research for 3 years at the University of Colorado Cancer Center. In the same role in the TCI, Dr. Goodman has been able to further expand on the work she was doing in Colorado and has focused on five major goals: 1) to expand access to clinical trials across the Mount Sinai Health System (MSHS); 2) to increase the numbers of NCI-sponsored trials performed across the MSHS; 3) to address the need for more oversight and integration of clinical trial services provided across the MSHS; 4) to support junior faculty to develop investigator-initiated trials (IITs) and present concepts to the Experimental Therapeutic Clinical Trials Network (ETCTN) for potential support; and, 5) to increase minority recruitment to TCI clinical trials. Institutionally, she has been the local PI of numerous National Clinical Trials Network (NCTN) studies at several NCI-designated cancer centers and is currently the Mount Sinai PI for one ECOG/ACRIN trial and one ETCTN trial and serves as the PI for the Early Drug Development Opportunity Program (EDDOP) at Mount Sinai. In addition, she is a national leader in the NCTN both through her involvement in the GI committees of the Alliance for Clinical Trials in Oncology and the NRG Oncology, as well as her role as the co-chair of the NCI Gastrointestinal Steering Committee. She has nicely bridged the work she has done nationally with her institutional AD of Clinical Research position. She brings her expertise in clinical trial development and oversight which she gained as the National Study Chair of the CALGB/Alliance 80803, a Phase II trial that evaluated PET-directed therapy for esophageal cancer, and the National Radiation Oncology Principal Investigator of the RTOG/NRG 0848, a large Phase III trial investigating the role of adjuvant chemoradiation in resectable pancreas cancer. Her overarching goal as a senior leader in the TCI is to support the development of both IITs and NCI-funded cooperative group clinical trials that will further advance the fight against cancer. The R50 funding mechanism will undoubtedly help foster her ability to expand NCI-funded oncology clinical research at Mount Sinai Hospital and expand access to these trials across the MSHS. Dr. Goodman is uniquely positioned for this award with both her institutional and national service focused on developing and supporting cancer clinical research.

ABSTRACT Dr. Karyn Goodman plays a critical role in Tisch Cancer Institute’s (TCI) cancer clinical trial program and in supporting NCI-funded clinical trials. She has demonstrated a long-term commitment to this work through her previous role as Associate Director (AD) of Clinical Research for 3 years at the University of Colorado Cancer Center. In the same role in the TCI, Dr. Goodman has been able to further expand on the work she was doing in Colorado and has focused on five major goals: 1) to expand access to clinical trials across the Mount Sinai Health System (MSHS); 2) to increase the numbers of NCI-sponsored trials performed across the MSHS; 3) to address the need for more oversight and integration of clinical trial services provided across the MSHS; 4) to support junior faculty to develop investigator-initiated trials (IITs) and present concepts to the Experimental Therapeutic Clinical Trials Network (ETCTN) for potential support; and, 5) to increase minority recruitment to TCI clinical trials. Institutionally, she has been the local PI of numerous National Clinical Trials Network (NCTN) studies at several NCI-designated cancer centers and is currently the Mount Sinai PI for one ECOG/ACRIN trial and one ETCTN trial and serves as the PI for the Early Drug Development Opportunity Program (EDDOP) at Mount Sinai. In addition, she is a national leader in the NCTN both through her involvement in the GI committees of the Alliance for Clinical Trials in Oncology and the NRG Oncology, as well as her role as the co-chair of the NCI Gastrointestinal Steering Committee. She has nicely bridged the work she has done nationally with her institutional AD of Clinical Research position. She brings her expertise in clinical trial development and oversight which she gained as the National Study Chair of the CALGB/Alliance 80803, a Phase II trial that evaluated PET-directed therapy for esophageal cancer, and the National Radiation Oncology Principal Investigator of the RTOG/NRG 0848, a large Phase III trial investigating the role of adjuvant chemoradiation in resectable pancreas cancer. Her overarching goal as a senior leader in the TCI is to support the development of both IITs and NCI-funded cooperative group clinical trials that will further advance the fight against cancer. The R50 funding mechanism will undoubtedly help foster her ability to expand NCI-funded oncology clinical research at Mount Sinai Hospital and expand access to these trials across the MSHS. Dr. Goodman is uniquely positioned for this award with both her institutional and national service focused on developing and supporting cancer clinical research.