University of Washington Developmental AIDS Research Center for Mental Health (UW ARCH)

华盛顿大学心理健康发展艾滋病研究中心 (UW ARCH)

• 批准号: 10569065
• 负责人: Susan Marie Graham
• 金额: $ 97.18万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-04-01 至 2025-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10569065
• 关键词: AIDS prevention; Acquired Immunodeficiency Syndrome; Address; Applied Research; Behavioral Sciences; Caring; Clinical; Communities; Complex; Consultations; Country; County; Development; Discrimination; Dissemination and Implementation; Epidemic; Epidemiology; Geography; Goals; HIV; HIV risk; Healthcare; High Prevalence; Incidence; Inequity; Infrastructure; Institution; Intervention; Leadership; Learning; Measurement; Medical; Mental Depression; Mental Health; Mental Health Services; Mental association; Mental disorders; Mentors; Mentorship; Methods; Mission; Modeling; Pathway interactions; Patients; Persons; Populations at Risk; Poverty; Practice based research; Prevention; Prevention strategy; Primary Care; Process; Provider; Research; Research Design; Research Personnel; Research Support; Resources; Risk; Science; Services; Statistical Methods; Strategic Planning; Substance Use Disorder; Substance abuse problem; Symptoms; Technology; Testing; Training; Training Programs; Trauma; Underrepresented Populations; United States; Universities; Vulnerable Populations; Washington; Work; antiretroviral therapy; collaborative care; community engagement; comorbidity; disparity reduction; driving force; effective therapy; evidence base; experience; health care delivery; implementation science; innovation; integrated care; marginalized population; mental health center; mortality; multidisciplinary; next generation; novel; person centered; psychologic; scale up; social science research; social stigma; socioeconomic disadvantage; theories; therapy development; traumatic stress; treatment strategy; user centered design

OVERALL ABSTRACT The proposed University of Washington (UW) Developmental AIDS Research Center (D-ARC) responds to the global HIV epidemic at a critical stage. Though more than 21 million people around the world receive antiretroviral therapy, the most marginalized populations continue to experience high incidence, less access to effective prevention and care, and greater mortality. Unmet needs persist in high-prevalence countries as well as “geographic hotspots” in the US such as Seattle's King County. Intersecting stigma, trauma, poverty, and substance abuse increase risk for mental illnesses, yet the effective treatments available are rarely implemented. The proposed D-ARC aims to address these challenges by catalyzing research that helps end the epidemic, with a focus on integrating care for mental disorders into HIV prevention and treatment strategies. Furthermore, Center investigators will support and apply the science of dissemination and implementation, with the overall goal of bringing such interventions to scale. The D-ARC aims to fill a gap in HIV behavioral science research at UW by capitalizing on the considerable strengths of UW's HIV expertise and bridging this with UW's longstanding leadership in the development and delivery of models of integrated mental health care. By combining UW expertise in (a) HIV research and (b) mental health care—now siloed geographically, programmatically, and conceptually—the Center will be a synergistic force capable of realizing is mission of Implementing Innovative Impactful Integrated Interventions. The proposed infrastructure capitalizes on the strengths of local expertise and broad ties with global collaborative networks, adding value to UW through the Center's administration, research support, and training missions, buttressed through additional institutional commitments of $762,296. Cross-cutting themes of the D-ARC are (a) leveraging local and global bidirectional pathways to learning and innovation by engaging communities of providers and (b) addressing inequities by testing research solutions that reduce disparities. Four proposed Cores address the Overall specific aims: 1) Catalyze and support innovative and impactful research to curb the HIV epidemic, with a focus on integrated intervention strategies (Administrative Core); 2) Provide needed technical assistance and training on research design, measurement, theory and novel statistical methods relevant to mental health and HIV research (Methods Core); 3) Stimulate practice-based research that promotes effective integrated mental health services in HIV care settings and disseminate findings broadly (Integrated Care Core); and 4) Nurture the Next Generation of diverse, multidisciplinary HIV researchers through training and innovative mentorship of early stage investigators and mentors (Developmental Core).

总体摘要 拟议的华盛顿大学艾滋病发展研究中心(D-ARC)回应 全球艾滋病毒疫情正处于关键阶段。尽管全世界有2100多万人接受抗逆转录病毒治疗 治疗中，最边缘化的人群继续经历高发病率，较少获得有效治疗 预防和护理，以及更高的死亡率。未得到满足的需求在高流行率国家以及 美国的“地理热点”，比如西雅图的金县。交叉的耻辱，创伤，贫穷和 物质滥用增加了患精神疾病的风险，但可用的有效治疗很少得到实施。 拟议的D-ARC旨在通过催化有助于结束 流行病，重点是将精神障碍的护理纳入艾滋病毒的预防和治疗 战略。此外，中心调查人员将支持和应用传播科学和 实施，总体目标是使这类干预措施规模化。D-ARC旨在填补一个空白 通过利用威斯康星大学艾滋病毒专业知识的相当大优势，在威斯康星州大学进行艾滋病毒行为科学研究 并将这一点与UW在开发和交付集成车型方面的长期领先地位联系起来 心理健康护理。通过将威斯康星大学在(A)艾滋病毒研究和(B)精神卫生保健方面的专业知识结合起来--现在是孤立的 在地理上、方案上和概念上--中心将成为一股能够实现以下目标的协同力量 是实施创新有效的综合干预措施的使命。拟议的基础设施充分利用了 关于本地专业知识和与全球协作网络的广泛联系的优势，通过以下方式为UW增加价值 该中心的管理、研究支持和培训任务，由更多的机构提供支持 承付款762,296美元。发展区域资源中心的交叉主题是：(A)利用地方和全球双向 通过吸引提供者社区的参与来实现学习和创新的途径以及(B)通过以下方式解决不平等问题 测试缩小差距的研究解决方案。拟议的四个核心涉及总体具体目标：1) 催化和支持遏制艾滋病毒流行的创新和有影响力的研究，重点是综合研究 干预战略(行政核心)；2)提供必要的技术援助和研究培训 与心理健康和艾滋病毒研究有关的设计、测量、理论和新的统计方法(方法 核心)；3)鼓励以实践为基础的研究，以促进有效的艾滋病毒综合精神健康服务 护理环境和广泛传播研究结果(综合护理核心)；以及4)培养下一代 通过对早期调查人员的培训和创新指导，实现多样化、多学科的艾滋病毒研究人员 和导师(发展核心)。