Research methodology to assess surgery for ulnar neuropathy at the elbow

项目摘要/摘要： 肘部尺神经病是第二常见的压迫性神经病。 在腕管综合征之后。男性的发病率是女性的三倍，为7.3万。 美国每年都有新的确诊病例。UNE不成比例地影响工作 个人，特别是在需要长时间或频繁屈肘的任务中。麻木 戒指和小手指刺痛，肘部疼痛，手臂失去知觉， 手和无名指是UNE的典型症状。严重的病例也可能 手部肌肉的运动缺陷。诊断是基于体征、症状和电诊断 学习。 最常见的手术治疗是尺骨原位(简单)减压术。 肘部神经或皮下前神经移位术。外科技术的选择 不同的外科医生有不同之处，没有明确的证据表明哪种手术更多 有效和适用于哪种类型的患者。 这项补充的父母资助，尺神经外科(SUN)研究 (1U01AR073485)是一项随机双盲优势临床试验，旨在比较 评价原位减压皮下前移位术的疗效 患者报告的结果和生理结果。本副刊建议提供一项特殊的 医科学生(经过硕士培训)，接受实践培训，并具备必要的技能 追求学术事业。具体地说，她将从中获得的学习和指导 经验将使她能够协助研究电诊断与 与尺神经病相关的参数、种族/民族差异和治疗结果。 此外，本补编将有助于编写关于上述专题的文献和 提高对UNE治疗中这些因素的认识。

Project Summary/Abstract: Ulnar neuropathy at the elbow (UNE) is the second most common compression neuropathy after carpal tunnel syndrome. It is three times more frequent in men than women with 73,000 new cases diagnosed in the United States each year. UNE disproportionately affects working individuals, particularly in tasks requiring prolonged or frequent flexion of the elbow. Numbness and tingling of the ring and little fingers, pain at the elbow, and loss of sensation over the arm, hand and ring fingers are the characteristic symptoms of UNE. Severe cases can also have motor deficit of the hand muscles. Diagnosis is based on signs, symptoms and electrodiagnostic studies. The most common surgical treatments for UNE are in-situ (simple) decompression of the ulnar nerve at the elbow or subcutaneous anterior nerve transposition. Choice of surgical technique differs among surgeons and there is no clear evidence regarding which procedure is more effective and for which type of patient. The parent grant for this supplement, the Surgery of the Ulnar Nerve (SUN) study (1U01AR073485) is a randomized double-blind superiority clinical trial to compare the effectiveness of in-situ decompression and subcutaneous anterior transposition by assessing patient-reported and physiologic outcomes. This supplement proposes to provide an exceptional medical student (with master’s training) with hands-on-training and skills necessary for her to pursue an academic career. Specifically, the learning and guidance she will gain from this experience will enable her to assist in investigating associations between electrodiagnostic parameters, racial/ethnic variations, and treatment outcomes related to ulnar neuropathy. Additionally, this supplement will contribute to literature on the above-mentioned topics and advance the understanding of these factors in UNE treatment.