Novel approaches for targeted sleep apnoea treatment and management

有针对性的睡眠呼吸暂停治疗和管理的新方法

• 批准号: nhmrc : 1196261
• 金额: $ 209.06万
• 依托单位国家: 澳大利亚
• 项目类别: Investigator Grants
• 财政年份: 2021
• 资助国家: 澳大利亚
• 起止时间: 2021-01-01 至 2025-12-31
• 项目状态: 未结题
• 来源: https://researchdata.edu.au/novel-approaches-targeted-treatment-management/1779114
• 关键词: Novel; approaches; targeted; sleep; apnoea

>1million Australian adults have obstructive sleep apnoea (OSA). OSA has several causes. Untreated OSA is associated with major health consequences. <50% of OSA patients tolerate the main therapy, continuous positive airway pressure. New treatments are urgently required. This proposal aims to use and develop novel approaches to identify the causes of OSA on a per patient basis, improve current therapies and management approaches and test if new targeted therapies can be used to treat OSA.

>100万澳大利亚成年人患有阻塞性睡眠呼吸暂停症（OSA）。OSA有几个原因。未经治疗的OSA与严重的健康后果有关。<50%的阻塞性睡眠呼吸暂停患者能耐受主要治疗，持续气道正压通气。迫切需要新的治疗方法。该提案旨在使用和开发新的方法，以确定每个患者的OSA原因，改进当前的治疗和管理方法，并测试新的靶向治疗是否可用于治疗OSA。