Integration of epigenetic and non-coding RNA mechanism in leukemia
Integration of epigenetic and non-coding RNA mechanism in leukemia
批准号:
10582327
负责人:
Sara E Meyer
金额:
$34.97万
依托单位国家:
美国
项目类别:
财政年份:
2023
资助国家:
美国
项目状态:
未结题
起止时间:
2023-07-01 至 2025-06-30
关键词:
Acute Myelocytic LeukemiaAdultAffectAgonistBindingBiotinylationCXCL9 geneCharacteristicsChemoresistanceChildClinicalClustered Regularly Interspaced Short Palindromic RepeatsCompensationCytotoxic ChemotherapyDNADNA MethylationDNA Modification MethylasesDNMT3aDNMT3a mutationDataDependenceDiseaseEpigenetic ProcessEventExhibitsFLT3 geneGene ExpressionGene Expression ProfileGene Expression RegulationGenesGenetic TranscriptionGrowthHematopoietic NeoplasmsHematopoietic stem cellsHumanIRAK4 geneImmune signalingMaintenanceMessenger RNAMethyltransferaseMicroRNAsMusMutationMyelogenousMyeloid LeukemiaOutcomeOutputPathogenesisPatientsPhosphotransferasesRELA geneReceptor Protein-Tyrosine KinasesReceptor SignalingRegulator GenesRepressionSignal TransductionTLR7 geneTestingTherapeuticToll-Like Receptor PathwayToll-like receptorsUntranslated RNAacute myeloid leukemia cellcell growthchemokinecytokinegenomic locushigh riskin vivoinnovationleukemialeukemia initiating cellleukemic stem cellleukemic transformationleukemogenesisloss of functionmouse modelmutantnoveloverexpressionrestorationself-renewalstemnesstherapeutic evaluation
中文摘要
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英文摘要
N/A
期刊论文(2)
专著(0)
科研奖励(0)
会议论文
Context is key for FLT3-ITD.
上下文是 FLT3-ITD 的关键。
DOI:
10.1182/blood.2022019135
发表时间:
2023
期刊:
Blood
影响因子:
20.3
作者:
[Meyer,SaraE]
通讯作者:
Meyer,SaraE
Integration of epigenetic and non-coding RNA mechanisms in leukemia
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批准号:10442752
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项目类别:
-
资助金额:$35.69万
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财政年份:2018
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负责人:Sara E Meyer
-
依托单位:
Integration of epigenetic and non-coding RNA mechanisms in leukemia
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批准号:10198862
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项目类别:
-
资助金额:$35.69万
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财政年份:2018
-
负责人:Sara E Meyer
-
依托单位:
海外基金